Predicted complex interactions
CCL27_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 86
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | TYR 124 | 3.32x32 | HBDonor |
| PHE 1 | NTc.Cm32 | TYR 124 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm32 | ARG 211 | 5.39x40 | VdWContact |
| PHE 1 | NTc.Cm32 | LEU 294 | 7.35x34 | Hydrophobic |
| PHE 1 | NTc.Cm32 | GLU 298 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm32 | GLU 298 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm32 | GLU 298 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 53 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 53 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 102 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 102 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 124 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 298 | 7.39x38 | Hydrophobic |
| LEU 2 | NTc.Cm31 | PHE 302 | 7.43x42 | Hydrophobic |
| LEU 2 | NTc.Cm31 | PHE 302 | 7.43x42 | VdWContact |
| LEU 3 | NTc.Cm30 | CYS 195 | 45.50x50 | VdWContact |
| LEU 3 | NTc.Cm30 | HIS 196 | 45.51x51 | Hydrophobic |
| LEU 3 | NTc.Cm30 | HIS 196 | 45.51x51 | VdWContact |
| PRO 5 | NTc.Cm28 | VAL 41 | 1.27x27 | Hydrophobic |
| PRO 5 | NTc.Cm28 | VAL 42 | 1.28x28 | Hydrophobic |
| PRO 5 | NTc.Cm28 | VAL 42 | 1.28x28 | VdWContact |
| PRO 5 | NTc.Cm28 | GLN 295 | 7.36x35 | VdWContact |
| SER 6 | NTc.Cm27 | LYS 38 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 38 | 1.24x24 | HBAcceptor |
| THR 7 | NTc.Cm26 | LYS 38 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm26 | VAL 42 | 1.28x28 | Hydrophobic |
| ALA 8 | NTc.Cm25 | LEU 35 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | LEU 35 | - | VdWContact |
| ALA 8 | NTc.Cm25 | CYS 36 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 36 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 36 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 36 | - | VdWContact |
| CYS 9 | NTc.Cm24 | LYS 38 | 1.24x24 | Anionic |
| THR 11 | NTc.Cm22 | CYS 36 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | CYS 36 | - | VdWContact |
| THR 11 | NTc.Cm22 | GLY 282 | - | VdWContact |
| THR 11 | NTc.Cm22 | SER 287 | 7.28x27 | VdWContact |
| GLN 12 | NTc.Cm21 | ALA 32 | - | VdWContact |
| GLN 12 | NTc.Cm21 | PHE 33 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | GLY 282 | - | VdWContact |
| LEU 13 | NTc.Cm20 | GLN 279 | 6.64x64 | VdWContact |
| TYR 14 | NTc.Cm19 | LEU 28 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 33 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 33 | - | PiStacking |
| TYR 14 | NTc.Cm19 | PHE 33 | - | VdWContact |
| ARG 15 | NTc.Cm18 | GLN 279 | 6.64x64 | HBDonor |
| ARG 15 | NTc.Cm18 | GLN 279 | 6.64x64 | VdWContact |
| SER 19 | NTc.Cm14 | TYR 24 | - | VdWContact |
| LYS 21 | NTc.Cm12 | SER 21 | - | VdWContact |
| LEU 22 | NTc.Cm11 | LEU 28 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | LEU 28 | - | VdWContact |
| LYS 25 | NTc.Cm8 | TYR 25 | - | HBDonor |
| LYS 25 | NTc.Cm8 | TYR 25 | - | Hydrophobic |
| LYS 25 | NTc.Cm8 | TYR 25 | - | VdWContact |
| GLU 30 | NTc.Cm3 | ASN 188 | - | VdWContact |
| ALA 34 | CX.5 | LYS 207 | 5.35x36 | VdWContact |
| ASP 35 | cxb1.1 | PHE 199 | - | HBAcceptor |
| ASP 35 | cxb1.1 | PHE 199 | - | VdWContact |
| ASP 35 | cxb1.1 | GLY 203 | 5.31x32 | VdWContact |
| ASP 35 | cxb1.1 | LYS 207 | 5.35x36 | HBAcceptor |
| ASP 35 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| GLY 36 | cxb1.2 | ALA 197 | 45.52x52 | VdWContact |
| GLY 36 | cxb1.2 | LYS 207 | 5.35x36 | VdWContact |
| CYS 38 | cxb1.6 | LYS 207 | 5.35x36 | VdWContact |
| HIS 39 | cxb1.7 | HIS 273 | 6.58x58 | HBAcceptor |
| HIS 39 | cxb1.7 | HIS 273 | 6.58x58 | Hydrophobic |
| HIS 39 | cxb1.7 | HIS 273 | 6.58x58 | VdWContact |
| HIS 39 | cxb1.7 | LEU 276 | 6.61x61 | Hydrophobic |
| HIS 39 | cxb1.7 | ASP 277 | 6.62x62 | HBDonor |
| HIS 39 | cxb1.7 | ASP 277 | 6.62x62 | VdWContact |
| LEU 40 | cxb1.8 | GLN 279 | 6.64x64 | Hydrophobic |
| LEU 40 | cxb1.8 | GLN 279 | 6.64x64 | VdWContact |
| VAL 44 | cxb1.15 | LEU 35 | - | Hydrophobic |
| ARG 50 | B1.2 | TYR 25 | - | VdWContact |
| ARG 50 | B1.2 | LEU 28 | - | HBDonor |
| ARG 50 | B1.2 | LEU 28 | - | VdWContact |
| ARG 50 | B1.2 | ASP 29 | - | Cationic |
| ARG 50 | B1.2 | ASP 29 | - | HBDonor |
| ARG 50 | B1.2 | ASP 29 | - | VdWContact |
| SER 51 | B1.3 | LEU 35 | - | HBAcceptor |
| SER 51 | B1.3 | LEU 35 | - | VdWContact |
| ILE 52 | B1.4 | LEU 28 | - | Hydrophobic |
| ILE 52 | B1.4 | PHE 33 | - | Hydrophobic |
| CYS 53 | B1.5 | PHE 33 | - | HBDonor |
| CYS 53 | B1.5 | PHE 33 | - | VdWContact |
| CYS 53 | B1.5 | LEU 35 | - | VdWContact |
