Predicted complex interactions
CCL8_HUMAN + CCRL2
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCRL2 View partner entry
- Partner description
- UniProt: O00421; Gene: ccrl2_human; Family: Chemokine
- Interactions detected
- 73
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 8 | NTc.Cm26 | GLN 27 | - | Hydrophobic |
| ILE 9 | NTc.Cm25 | CYS 28 | - | HBDonor |
| ILE 9 | NTc.Cm25 | CYS 28 | - | VdWContact |
| ILE 9 | NTc.Cm25 | LYS 30 | 1.24x24 | Hydrophobic |
| ILE 9 | NTc.Cm25 | LYS 30 | 1.24x24 | VdWContact |
| THR 10 | NTc.Cm24 | ALA 25 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | ALA 25 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLN 27 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | GLN 27 | - | VdWContact |
| CYS 11 | NTc.Cm23 | GLU 26 | - | HBDonor |
| CYS 11 | NTc.Cm23 | GLU 26 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LYS 30 | 1.24x24 | Anionic |
| CYS 11 | NTc.Cm23 | LYS 30 | 1.24x24 | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 28 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 28 | - | VdWContact |
| PHE 13 | NTc.Cm21 | SER 270 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| ASN 14 | NTc.Cm20 | SER 22 | - | HBDonor |
| ASN 14 | NTc.Cm20 | SER 22 | - | VdWContact |
| ASN 14 | NTc.Cm20 | SER 270 | - | HBAcceptor |
| ASN 14 | NTc.Cm20 | SER 270 | - | VdWContact |
| ILE 16 | NTc.Cm18 | LEU 20 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | LEU 20 | - | VdWContact |
| ILE 16 | NTc.Cm18 | ASP 23 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | ASP 23 | - | VdWContact |
| ARG 18 | NTc.Cm16 | LEU 15 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ILE 16 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ILE 16 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLU 19 | - | Cationic |
| ARG 18 | NTc.Cm16 | GLU 19 | - | HBDonor |
| ARG 18 | NTc.Cm16 | GLU 19 | - | VdWContact |
| ARG 18 | NTc.Cm16 | LEU 20 | - | VdWContact |
| ILE 20 | NTc.Cm14 | ILE 16 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | ILE 16 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | GLU 9 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 9 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 12 | - | HBDonor |
| ARG 24 | NTc.Cm10 | TYR 12 | - | VdWContact |
| ARG 24 | NTc.Cm10 | ASP 13 | - | Cationic |
| ARG 24 | NTc.Cm10 | ASP 13 | - | HBDonor |
| ARG 24 | NTc.Cm10 | ASP 13 | - | VdWContact |
| ARG 24 | NTc.Cm10 | ILE 16 | - | VdWContact |
| GLN 35 | CX.5 | LYS 30 | 1.24x24 | Hydrophobic |
| GLN 35 | CX.5 | LYS 30 | 1.24x24 | VdWContact |
| GLN 35 | CX.5 | ARG 185 | - | VdWContact |
| CYS 36 | cxb1.1 | LYS 30 | 1.24x24 | Anionic |
| CYS 36 | cxb1.1 | LYS 30 | 1.24x24 | VdWContact |
| ILE 42 | cxb1.10 | ALA 25 | - | Hydrophobic |
| ILE 42 | cxb1.10 | ALA 25 | - | VdWContact |
| ARG 47 | B1.1 | ASP 10 | - | Cationic |
| ARG 47 | B1.1 | ASP 13 | - | Cationic |
| ARG 47 | B1.1 | ASP 13 | - | HBDonor |
| ARG 47 | B1.1 | ASP 13 | - | VdWContact |
| ARG 47 | B1.1 | GLU 17 | - | Cationic |
| ARG 47 | B1.1 | GLU 17 | - | HBDonor |
| ARG 47 | B1.1 | GLU 17 | - | VdWContact |
| LYS 49 | B1.3 | GLU 17 | - | HBDonor |
| LYS 49 | B1.3 | GLU 17 | - | Hydrophobic |
| LYS 49 | B1.3 | GLU 17 | - | VdWContact |
| LYS 49 | B1.3 | LEU 20 | - | Hydrophobic |
| LYS 49 | B1.3 | GLU 24 | - | Cationic |
| LYS 49 | B1.3 | GLU 24 | - | HBDonor |
| LYS 49 | B1.3 | GLU 24 | - | VdWContact |
| GLU 50 | B1.4 | GLU 24 | - | VdWContact |
| GLU 50 | B1.4 | ALA 25 | - | HBAcceptor |
| GLU 50 | B1.4 | ALA 25 | - | Hydrophobic |
| GLU 50 | B1.4 | ALA 25 | - | VdWContact |
| VAL 51 | B1.5 | LEU 20 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 20 | - | VdWContact |
| VAL 51 | B1.5 | ASP 23 | - | Hydrophobic |
| CYS 52 | B1.6 | ASP 23 | - | HBDonor |
| CYS 52 | B1.6 | ASP 23 | - | VdWContact |
| CYS 52 | B1.6 | ALA 25 | - | VdWContact |
