Predicted complex interactions
CXCL12_HUMAN + CCRL2
SUMMARY
- Chemokine
- CXCL12_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCRL2 View partner entry
- Partner description
- UniProt: O00421; Gene: ccrl2_human; Family: Chemokine
- Interactions detected
- 75
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 8 | NTc.Cm22 | ASP 32 | 1.26x26 | Cationic |
| ARG 8 | NTc.Cm22 | GLN 34 | 1.28x28 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 34 | 1.28x28 | VdWContact |
| PRO 10 | NTc.Cm20 | LEU 20 | - | Hydrophobic |
| ARG 12 | NTc.Cm18 | ASP 32 | 1.26x26 | Cationic |
| ARG 12 | NTc.Cm18 | ASP 32 | 1.26x26 | HBDonor |
| ARG 12 | NTc.Cm18 | ASP 32 | 1.26x26 | VdWContact |
| ARG 12 | NTc.Cm18 | ASP 176 | - | HBAcceptor |
| ARG 12 | NTc.Cm18 | ASP 176 | - | VdWContact |
| PHE 13 | NTc.Cm17 | LYS 30 | 1.24x24 | Hydrophobic |
| PHE 13 | NTc.Cm17 | GLU 175 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | GLU 175 | - | VdWContact |
| PHE 13 | NTc.Cm17 | ARG 185 | - | PiCation |
| PHE 13 | NTc.Cm17 | ARG 185 | - | VdWContact |
| PHE 14 | NTc.Cm16 | MET 174 | - | HBDonor |
| PHE 14 | NTc.Cm16 | MET 174 | - | Hydrophobic |
| PHE 14 | NTc.Cm16 | MET 174 | - | VdWContact |
| GLU 15 | NTc.Cm15 | GLN 173 | - | HBAcceptor |
| GLU 15 | NTc.Cm15 | GLN 173 | - | VdWContact |
| GLU 15 | NTc.Cm15 | PRO 190 | - | Hydrophobic |
| GLU 15 | NTc.Cm15 | PRO 190 | - | VdWContact |
| GLU 15 | NTc.Cm15 | ALA 191 | - | HBAcceptor |
| GLU 15 | NTc.Cm15 | ALA 191 | - | VdWContact |
| HIS 17 | NTc.Cm13 | LYS 171 | - | Hydrophobic |
| HIS 17 | NTc.Cm13 | LYS 171 | - | VdWContact |
| HIS 17 | NTc.Cm13 | PRO 190 | - | Hydrophobic |
| HIS 17 | NTc.Cm13 | PRO 190 | - | VdWContact |
| HIS 17 | NTc.Cm13 | ASP 192 | 5.30x31 | VdWContact |
| VAL 18 | NTc.Cm12 | ASP 192 | 5.30x31 | VdWContact |
| ALA 19 | NTc.Cm11 | ASP 192 | 5.30x31 | HBDonor |
| ALA 19 | NTc.Cm11 | ASP 192 | 5.30x31 | VdWContact |
| ARG 20 | NTc.Cm10 | ASP 10 | - | Cationic |
| ARG 20 | NTc.Cm10 | TYR 12 | - | Hydrophobic |
| ARG 20 | NTc.Cm10 | TYR 12 | - | VdWContact |
| VAL 23 | NTc.Cm7 | TYR 12 | - | Hydrophobic |
| VAL 23 | NTc.Cm7 | TYR 12 | - | VdWContact |
| HIS 25 | NTc.Cm5 | ASP 13 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | ASP 13 | - | VdWContact |
| LEU 26 | NTc.Cm4 | TYR 12 | - | Hydrophobic |
| LEU 26 | NTc.Cm4 | ASP 13 | - | HBDonor |
| LEU 26 | NTc.Cm4 | ASP 13 | - | VdWContact |
| LEU 26 | NTc.Cm4 | LEU 15 | - | HBAcceptor |
| LYS 27 | NTc.Cm3 | LEU 15 | - | VdWContact |
| LYS 27 | NTc.Cm3 | LEU 20 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | LEU 20 | - | VdWContact |
| ILE 28 | NTc.Cm2 | VAL 14 | - | Hydrophobic |
| ILE 28 | NTc.Cm2 | VAL 14 | - | VdWContact |
| ILE 28 | NTc.Cm2 | ILE 16 | - | Hydrophobic |
| LEU 29 | NTc.Cm1 | LEU 20 | - | Hydrophobic |
| LEU 29 | NTc.Cm1 | LEU 20 | - | VdWContact |
| ALA 35 | cxb1.5 | GLN 177 | - | Hydrophobic |
| ALA 35 | cxb1.5 | GLN 177 | - | VdWContact |
| ARG 41 | cxb1.15 | GLU 24 | - | Cationic |
| ARG 41 | cxb1.15 | GLU 24 | - | HBDonor |
| ARG 41 | cxb1.15 | GLU 24 | - | VdWContact |
| LEU 42 | cxb1.16 | ALA 191 | - | Hydrophobic |
| ARG 47 | B1.5 | GLU 265 | 6.62x62 | Cationic |
| ARG 47 | B1.5 | GLU 265 | 6.62x62 | HBDonor |
| ARG 47 | B1.5 | GLU 265 | 6.62x62 | VdWContact |
| GLN 48 | B1.6 | ALA 25 | - | VdWContact |
| VAL 49 | B1.7 | ALA 191 | - | Hydrophobic |
| CYS 50 | b1b2.4 | GLN 27 | - | VdWContact |
| ASP 52 | b1b2.8 | MET 174 | - | VdWContact |
| ASP 52 | b1b2.8 | TYR 179 | - | HBAcceptor |
| ASP 52 | b1b2.8 | TYR 179 | - | VdWContact |
| LYS 54 | b1b2.10 | MET 174 | - | Hydrophobic |
| LYS 54 | b1b2.10 | MET 174 | - | VdWContact |
| LYS 54 | b1b2.10 | TYR 179 | - | Hydrophobic |
| LYS 54 | b1b2.10 | TYR 179 | - | VdWContact |
| TYR 61 | B2.4 | TYR 12 | - | HBDonor |
| TYR 61 | B2.4 | TYR 12 | - | Hydrophobic |
| TYR 61 | B2.4 | TYR 12 | - | VdWContact |
| TYR 61 | B2.4 | VAL 14 | - | Hydrophobic |
| TYR 61 | B2.4 | VAL 14 | - | VdWContact |
| ALA 65 | b2b3.3 | VAL 14 | - | Hydrophobic |
