Predicted complex interactions
CCL3_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | TYR 53 | 1.39x39 | HBDonor |
| SER 1 | NTc.Cm33 | TYR 53 | 1.39x39 | VdWContact |
| SER 1 | NTc.Cm33 | TRP 102 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm33 | GLU 298 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm33 | GLU 298 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm32 | ARG 211 | 5.39x40 | VdWContact |
| LEU 2 | NTc.Cm32 | LEU 270 | 6.55x55 | Hydrophobic |
| LEU 2 | NTc.Cm32 | LEU 294 | 7.35x34 | Hydrophobic |
| LEU 2 | NTc.Cm32 | LEU 294 | 7.35x34 | VdWContact |
| LEU 2 | NTc.Cm32 | GLU 298 | 7.39x38 | HBDonor |
| LEU 2 | NTc.Cm32 | GLU 298 | 7.39x38 | VdWContact |
| ALA 3 | NTc.Cm31 | LEU 49 | 1.35x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 295 | 7.36x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 295 | 7.36x35 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 298 | 7.39x38 | HBDonor |
| ALA 3 | NTc.Cm31 | GLU 298 | 7.39x38 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLU 298 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | TRP 102 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm30 | VAL 106 | 2.64x64 | Hydrophobic |
| ALA 4 | NTc.Cm30 | VAL 106 | 2.64x64 | VdWContact |
| ASP 5 | NTc.Cm29 | HIS 196 | 45.51x51 | Hydrophobic |
| ASP 5 | NTc.Cm29 | HIS 196 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm28 | VAL 41 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm28 | ASP 291 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | GLN 295 | 7.36x35 | HBAcceptor |
| THR 6 | NTc.Cm28 | GLN 295 | 7.36x35 | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 38 | 1.24x24 | VdWContact |
| THR 8 | NTc.Cm26 | LYS 38 | 1.24x24 | HBAcceptor |
| THR 8 | NTc.Cm26 | LYS 38 | 1.24x24 | VdWContact |
| THR 8 | NTc.Cm26 | VAL 42 | 1.28x28 | Hydrophobic |
| ALA 9 | NTc.Cm25 | LEU 35 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | LEU 35 | - | VdWContact |
| ALA 9 | NTc.Cm25 | CYS 36 | - | VdWContact |
| CYS 10 | NTc.Cm24 | CYS 36 | - | HBAcceptor |
| CYS 10 | NTc.Cm24 | CYS 36 | - | HBDonor |
| CYS 10 | NTc.Cm24 | CYS 36 | - | VdWContact |
| CYS 10 | NTc.Cm24 | LYS 38 | 1.24x24 | Anionic |
| PHE 12 | NTc.Cm22 | CYS 36 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 36 | - | VdWContact |
| PHE 12 | NTc.Cm22 | LEU 276 | 6.61x61 | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 284 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 284 | 7.25x24 | VdWContact |
| PHE 12 | NTc.Cm22 | SER 287 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm21 | MET 34 | - | VdWContact |
| THR 15 | NTc.Cm19 | TYR 27 | - | HBAcceptor |
| THR 15 | NTc.Cm19 | TYR 27 | - | VdWContact |
| SER 16 | NTc.Cm18 | TYR 27 | - | HBDonor |
| SER 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ARG 17 | NTc.Cm17 | TYR 27 | - | Hydrophobic |
| ILE 19 | NTc.Cm15 | TYR 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm15 | TYR 24 | - | VdWContact |
| ILE 19 | NTc.Cm15 | LEU 28 | - | Hydrophobic |
| PRO 20 | NTc.Cm14 | TYR 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm14 | TYR 24 | - | VdWContact |
| PHE 23 | NTc.Cm10 | TYR 24 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | TYR 24 | - | PiStacking |
| PHE 23 | NTc.Cm10 | TYR 25 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | TYR 25 | - | VdWContact |
| GLU 29 | NTc.Cm4 | ASN 188 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | ASN 188 | - | VdWContact |
| SER 32 | NTc.Cm1 | ASP 198 | - | VdWContact |
| SER 32 | NTc.Cm1 | PHE 199 | - | HBAcceptor |
| SER 32 | NTc.Cm1 | PHE 199 | - | VdWContact |
| SER 32 | NTc.Cm1 | LYS 207 | 5.35x36 | HBAcceptor |
| SER 32 | NTc.Cm1 | LYS 207 | 5.35x36 | VdWContact |
| GLN 33 | CX.1 | HIS 196 | 45.51x51 | Hydrophobic |
| GLN 33 | CX.1 | HIS 196 | 45.51x51 | VdWContact |
| GLN 33 | CX.1 | LYS 207 | 5.35x36 | HBAcceptor |
| GLN 33 | CX.1 | LYS 207 | 5.35x36 | VdWContact |
| LYS 36 | cxb1.2 | GLN 279 | 6.64x64 | VdWContact |
| ILE 40 | cxb1.8 | LEU 35 | - | Hydrophobic |
| ILE 40 | cxb1.8 | LEU 35 | - | VdWContact |
| THR 43 | cxb1.14 | LEU 28 | - | Hydrophobic |
| ARG 45 | cxb1.16 | TYR 25 | - | CationPi |
| ARG 45 | cxb1.16 | TYR 25 | - | Hydrophobic |
| ARG 45 | cxb1.16 | TYR 25 | - | VdWContact |
| ARG 47 | B1.2 | TYR 25 | - | HBDonor |
| ARG 47 | B1.2 | TYR 25 | - | VdWContact |
| ARG 47 | B1.2 | LEU 28 | - | VdWContact |
| ARG 47 | B1.2 | ASP 29 | - | Cationic |
| ARG 47 | B1.2 | ASP 29 | - | VdWContact |
| GLN 48 | B1.3 | ALA 32 | - | VdWContact |
| GLN 48 | B1.3 | LEU 35 | - | Hydrophobic |
| GLN 48 | B1.3 | LEU 35 | - | VdWContact |
| GLN 48 | B1.3 | ARG 37 | - | HBAcceptor |
| GLN 48 | B1.3 | ARG 37 | - | VdWContact |
| VAL 49 | B1.4 | LEU 28 | - | Hydrophobic |
| VAL 49 | B1.4 | LEU 28 | - | VdWContact |
| VAL 49 | B1.4 | VAL 31 | - | Hydrophobic |
