Predicted complex interactions
CXCL8_HUMAN + CCRL2
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCRL2 View partner entry
- Partner description
- UniProt: O00421; Gene: ccrl2_human; Family: Chemokine
- Interactions detected
- 131
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 7 | NTc.Cm27 | MET 1 | - | VdWContact |
| CYS 14 | NTc.Cm20 | ASP 23 | - | VdWContact |
| CYS 14 | NTc.Cm20 | GLU 24 | - | HBDonor |
| CYS 14 | NTc.Cm20 | GLU 24 | - | Hydrophobic |
| CYS 14 | NTc.Cm20 | GLU 24 | - | VdWContact |
| CYS 16 | NTc.Cm18 | GLU 24 | - | HBAcceptor |
| CYS 16 | NTc.Cm18 | GLU 24 | - | VdWContact |
| CYS 16 | NTc.Cm18 | ALA 25 | - | Hydrophobic |
| CYS 16 | NTc.Cm18 | ALA 25 | - | VdWContact |
| CYS 16 | NTc.Cm18 | GLU 26 | - | Hydrophobic |
| CYS 16 | NTc.Cm18 | GLU 26 | - | VdWContact |
| ILE 17 | NTc.Cm17 | GLU 24 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | GLU 24 | - | VdWContact |
| ILE 17 | NTc.Cm17 | ALA 25 | - | VdWContact |
| ILE 17 | NTc.Cm17 | GLU 26 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | GLU 26 | - | VdWContact |
| ILE 17 | NTc.Cm17 | GLN 27 | - | VdWContact |
| LYS 18 | NTc.Cm16 | GLU 24 | - | VdWContact |
| LYS 18 | NTc.Cm16 | ALA 25 | - | VdWContact |
| LYS 18 | NTc.Cm16 | GLU 26 | - | HBDonor |
| LYS 18 | NTc.Cm16 | GLU 26 | - | VdWContact |
| LYS 18 | NTc.Cm16 | GLN 27 | - | HBAcceptor |
| LYS 18 | NTc.Cm16 | GLN 27 | - | HBDonor |
| LYS 18 | NTc.Cm16 | GLN 27 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | GLN 27 | - | VdWContact |
| LYS 18 | NTc.Cm16 | ASP 29 | - | Cationic |
| LYS 18 | NTc.Cm16 | ASP 29 | - | HBDonor |
| LYS 18 | NTc.Cm16 | ASP 29 | - | VdWContact |
| THR 19 | NTc.Cm15 | LEU 20 | - | HBDonor |
| THR 19 | NTc.Cm15 | LEU 20 | - | VdWContact |
| THR 19 | NTc.Cm15 | GLU 21 | - | VdWContact |
| THR 19 | NTc.Cm15 | SER 22 | - | VdWContact |
| THR 19 | NTc.Cm15 | ALA 25 | - | Hydrophobic |
| THR 19 | NTc.Cm15 | ALA 25 | - | VdWContact |
| THR 19 | NTc.Cm15 | GLN 27 | - | HBAcceptor |
| THR 19 | NTc.Cm15 | GLN 27 | - | VdWContact |
| TYR 20 | NTc.Cm14 | LEU 20 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | LEU 20 | - | VdWContact |
| TYR 20 | NTc.Cm14 | LYS 30 | 1.24x24 | Hydrophobic |
| TYR 20 | NTc.Cm14 | LYS 30 | 1.24x24 | PiCation |
| TYR 20 | NTc.Cm14 | LYS 30 | 1.24x24 | VdWContact |
| SER 21 | NTc.Cm13 | GLU 19 | - | VdWContact |
| SER 21 | NTc.Cm13 | LEU 20 | - | HBAcceptor |
| SER 21 | NTc.Cm13 | LEU 20 | - | VdWContact |
| LYS 22 | NTc.Cm12 | GLU 19 | - | Cationic |
| LYS 22 | NTc.Cm12 | GLU 19 | - | HBDonor |
| LYS 22 | NTc.Cm12 | GLU 19 | - | VdWContact |
| LYS 22 | NTc.Cm12 | ASP 32 | 1.26x26 | Cationic |
| LYS 22 | NTc.Cm12 | ASP 32 | 1.26x26 | HBDonor |
| LYS 22 | NTc.Cm12 | ASP 32 | 1.26x26 | VdWContact |
| LYS 22 | NTc.Cm12 | GLN 34 | 1.28x28 | VdWContact |
| LYS 22 | NTc.Cm12 | ARG 185 | - | VdWContact |
| PRO 23 | NTc.Cm11 | GLY 18 | - | VdWContact |
| PRO 23 | NTc.Cm11 | GLU 19 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | ASP 176 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | LEU 20 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TYR 12 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | GLU 175 | - | HBDonor |
| HIS 25 | NTc.Cm9 | GLU 175 | - | VdWContact |
| PRO 26 | NTc.Cm8 | TYR 12 | - | Hydrophobic |
| LYS 27 | NTc.Cm7 | TYR 12 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | PRO 190 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | PRO 190 | - | VdWContact |
| PHE 28 | NTc.Cm6 | ASP 192 | 5.30x31 | VdWContact |
| GLU 31 | NTc.Cm3 | TYR 4 | - | Hydrophobic |
| GLU 31 | NTc.Cm3 | TYR 4 | - | VdWContact |
| GLU 31 | NTc.Cm3 | THR 5 | - | VdWContact |
| LEU 32 | NTc.Cm2 | THR 5 | - | HBAcceptor |
| LEU 32 | NTc.Cm2 | THR 5 | - | HBDonor |
| LEU 32 | NTc.Cm2 | THR 5 | - | VdWContact |
| ARG 33 | NTc.Cm1 | ASN 3 | - | VdWContact |
| ARG 33 | NTc.Cm1 | TYR 4 | - | HBDonor |
| ARG 33 | NTc.Cm1 | TYR 4 | - | Hydrophobic |
| ARG 33 | NTc.Cm1 | TYR 4 | - | VdWContact |
| GLU 36 | CX.5 | MET 1 | - | Anionic |
| GLU 36 | CX.5 | MET 1 | - | HBAcceptor |
| GLU 36 | CX.5 | MET 1 | - | VdWContact |
| ALA 42 | cxb1.8 | ASP 23 | - | VdWContact |
| ASN 43 | cxb1.10 | ASP 23 | - | HBDonor |
| ASN 43 | cxb1.10 | ASP 23 | - | Hydrophobic |
| ASN 43 | cxb1.10 | ASP 23 | - | VdWContact |
| GLU 45 | cxb1.14 | ASP 23 | - | VdWContact |
| LEU 50 | B1.3 | ALA 191 | - | Hydrophobic |
| SER 51 | B1.4 | ASP 192 | 5.30x31 | VdWContact |
| ASP 52 | B1.5 | ALA 191 | - | VdWContact |
| ASP 52 | B1.5 | THR 194 | 5.32x33 | Hydrophobic |
| ASP 52 | B1.5 | THR 194 | 5.32x33 | VdWContact |
| ARG 54 | B1.7 | ALA 191 | - | VdWContact |
| LEU 56 | b1b2.6 | LYS 30 | 1.24x24 | VdWContact |
| CYS 57 | b1b2.7 | LEU 20 | - | VdWContact |
| CYS 57 | b1b2.7 | ALA 25 | - | Hydrophobic |
| CYS 57 | b1b2.7 | ALA 25 | - | VdWContact |
| LEU 58 | b1b2.8 | LEU 20 | - | Hydrophobic |
| LEU 58 | b1b2.8 | LEU 20 | - | VdWContact |
| LEU 58 | b1b2.8 | SER 22 | - | VdWContact |
| ASP 59 | b1b2.9 | GLU 21 | - | Hydrophobic |
| ASP 59 | b1b2.9 | GLU 21 | - | VdWContact |
| ASP 59 | b1b2.9 | SER 22 | - | VdWContact |
| GLU 62 | b1b2.13 | GLY 18 | - | VdWContact |
| GLU 62 | b1b2.13 | GLU 19 | - | HBAcceptor |
| GLU 62 | b1b2.13 | GLU 19 | - | VdWContact |
| TRP 64 | b1b2.16 | ILE 16 | - | Hydrophobic |
| TRP 64 | b1b2.16 | ILE 16 | - | VdWContact |
| TRP 64 | b1b2.16 | GLY 18 | - | VdWContact |
| TRP 64 | b1b2.16 | GLU 19 | - | HBDonor |
| TRP 64 | b1b2.16 | GLU 19 | - | VdWContact |
| TRP 64 | b1b2.16 | LEU 20 | - | Hydrophobic |
| TRP 64 | b1b2.16 | LEU 20 | - | VdWContact |
| ARG 67 | B2.3 | VAL 14 | - | Hydrophobic |
| ARG 67 | B2.3 | VAL 14 | - | VdWContact |
| ARG 67 | B2.3 | ILE 16 | - | Hydrophobic |
| ARG 67 | B2.3 | ILE 16 | - | VdWContact |
| VAL 68 | B2.4 | ILE 16 | - | Hydrophobic |
| VAL 68 | B2.4 | ILE 16 | - | VdWContact |
| LYS 71 | b2b3.2 | TYR 12 | - | HBDonor |
| LYS 71 | b2b3.2 | TYR 12 | - | VdWContact |
| LYS 71 | b2b3.2 | VAL 14 | - | HBDonor |
| LYS 71 | b2b3.2 | VAL 14 | - | Hydrophobic |
| LYS 71 | b2b3.2 | VAL 14 | - | VdWContact |
| PHE 72 | b2b3.4 | THR 5 | - | VdWContact |
| PHE 72 | b2b3.4 | ALA 7 | - | Hydrophobic |
| PHE 72 | b2b3.4 | ALA 7 | - | VdWContact |
| LEU 73 | b2b3.11 | THR 5 | - | Hydrophobic |
| ARG 75 | B3.1 | ALA 7 | - | HBDonor |
| ARG 75 | B3.1 | ALA 7 | - | VdWContact |
| ARG 75 | B3.1 | PRO 8 | - | Hydrophobic |
| ARG 75 | B3.1 | PRO 8 | - | VdWContact |
| ARG 75 | B3.1 | GLU 9 | - | Cationic |
| ARG 75 | B3.1 | GLU 9 | - | HBDonor |
| ARG 75 | B3.1 | GLU 9 | - | VdWContact |
| ALA 76 | B3.2 | THR 5 | - | Hydrophobic |
