Predicted complex interactions
CCL21_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 2 | NTc.Cm29 | LEU 176 | 45.51x51 | Hydrophobic |
| ASP 2 | NTc.Cm29 | TYR 179 | - | HBAcceptor |
| ASP 2 | NTc.Cm29 | TYR 179 | - | VdWContact |
| ASP 2 | NTc.Cm29 | ARG 191 | 5.38x39 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 191 | 5.38x39 | HBAcceptor |
| ASP 2 | NTc.Cm29 | ARG 191 | 5.38x39 | VdWContact |
| ALA 5 | NTc.Cm26 | ILE 23 | 1.24x24 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ILE 23 | 1.24x24 | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 27 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm26 | VAL 27 | 1.28x28 | VdWContact |
| GLN 6 | NTc.Cm25 | ILE 23 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 21 | - | VdWContact |
| ASP 7 | NTc.Cm24 | TYR 22 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ILE 23 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm24 | ILE 23 | 1.24x24 | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 21 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 21 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 21 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 21 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 265 | 7.25x24 | Hydrophobic |
| SER 13 | NTc.Cm18 | ASP 15 | - | HBDonor |
| SER 13 | NTc.Cm18 | ASP 15 | - | VdWContact |
| SER 13 | NTc.Cm18 | ALA 18 | - | VdWContact |
| GLN 14 | NTc.Cm17 | ASP 15 | - | HBDonor |
| GLN 14 | NTc.Cm17 | ASP 15 | - | VdWContact |
| ARG 15 | NTc.Cm16 | GLU 13 | - | Cationic |
| ARG 15 | NTc.Cm16 | GLU 13 | - | HBDonor |
| ARG 15 | NTc.Cm16 | GLU 13 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 15 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PHE 12 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | THR 9 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | PHE 12 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | PHE 12 | - | VdWContact |
| LYS 20 | NTc.Cm11 | THR 9 | - | Hydrophobic |
| LYS 20 | NTc.Cm11 | THR 9 | - | VdWContact |
| VAL 21 | NTc.Cm10 | PHE 12 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | PHE 12 | - | VdWContact |
| LEU 32 | CX.5 | TYR 179 | - | Hydrophobic |
| LEU 32 | CX.5 | GLN 184 | 5.31x32 | VdWContact |
| LEU 32 | CX.5 | PRO 188 | 5.35x36 | Hydrophobic |
| LEU 32 | CX.5 | PRO 188 | 5.35x36 | VdWContact |
| LEU 32 | CX.5 | LEU 258 | 6.62x62 | Hydrophobic |
| GLY 33 | cxb1.1 | ARG 268 | 7.28x27 | HBAcceptor |
| GLY 33 | cxb1.1 | ARG 268 | 7.28x27 | VdWContact |
| SER 35 | cxb1.5 | ASP 260 | 6.64x64 | HBDonor |
| SER 35 | cxb1.5 | ASP 260 | 6.64x64 | VdWContact |
| LEU 40 | cxb1.11 | ALA 20 | - | Hydrophobic |
| GLN 48 | B1.5 | PHE 12 | - | VdWContact |
| ALA 49 | B1.6 | TYR 14 | - | VdWContact |
| ALA 49 | B1.6 | GLU 19 | - | Hydrophobic |
| ALA 49 | B1.6 | GLU 19 | - | VdWContact |
| GLU 50 | B1.7 | GLU 19 | - | VdWContact |
| GLU 50 | B1.7 | ALA 20 | - | HBAcceptor |
| GLU 50 | B1.7 | ALA 20 | - | Hydrophobic |
| GLU 50 | B1.7 | ALA 20 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 14 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 14 | - | VdWContact |
| LEU 51 | b1b2.4 | ASP 15 | - | Hydrophobic |
| LEU 51 | b1b2.4 | ALA 18 | - | Hydrophobic |
| CYS 52 | b1b2.6 | ALA 18 | - | HBDonor |
| CYS 52 | b1b2.6 | ALA 18 | - | VdWContact |
| CYS 52 | b1b2.6 | ALA 20 | - | VdWContact |
| GLN 62 | B2.2 | PHE 4 | - | Hydrophobic |
| GLN 62 | B2.2 | PHE 4 | - | VdWContact |
| LEU 63 | B2.3 | PHE 4 | - | Hydrophobic |
| LEU 63 | B2.3 | PHE 4 | - | VdWContact |
| HIS 66 | B2.6 | PHE 4 | - | Hydrophobic |
| LYS 82 | H.2 | GLU 94 | - | Cationic |
| LYS 82 | H.2 | GLU 94 | - | Hydrophobic |
| LYS 82 | H.2 | GLU 94 | - | VdWContact |
| THR 102 | CT.12 | GLU 172 | - | VdWContact |
| ARG 104 | CT.14 | LYS 171 | - | Hydrophobic |
| ARG 104 | CT.14 | LYS 171 | - | VdWContact |
| ARG 104 | CT.14 | GLU 172 | - | HBDonor |
| ARG 104 | CT.14 | GLU 172 | - | Hydrophobic |
| ARG 104 | CT.14 | GLU 172 | - | VdWContact |
| SER 105 | CT.15 | LYS 171 | - | HBAcceptor |
| SER 105 | CT.15 | LYS 171 | - | VdWContact |
| SER 105 | CT.15 | LEU 176 | 45.51x51 | VdWContact |
| GLN 106 | CT.16 | LYS 171 | - | VdWContact |
| GLN 106 | CT.16 | GLU 172 | - | HBDonor |
| GLN 106 | CT.16 | GLU 172 | - | Hydrophobic |
| GLN 106 | CT.16 | GLU 172 | - | VdWContact |
| GLN 106 | CT.16 | GLU 174 | - | VdWContact |
| GLN 106 | CT.16 | LEU 176 | 45.51x51 | VdWContact |
| THR 107 | CT.17 | LYS 171 | - | Hydrophobic |
| THR 107 | CT.17 | LYS 171 | - | VdWContact |
| THR 107 | CT.17 | GLU 174 | - | HBDonor |
| THR 107 | CT.17 | GLU 174 | - | Hydrophobic |
| THR 107 | CT.17 | GLU 174 | - | VdWContact |
| THR 107 | CT.17 | CYS 175 | 45.50x50 | VdWContact |
| THR 107 | CT.17 | LEU 176 | 45.51x51 | Hydrophobic |
| THR 107 | CT.17 | LEU 176 | 45.51x51 | VdWContact |
| PRO 108 | CT.18 | TYR 90 | 2.63x63 | VdWContact |
| PRO 108 | CT.18 | CYS 175 | 45.50x50 | Hydrophobic |
| PRO 108 | CT.18 | CYS 175 | 45.50x50 | VdWContact |
| PRO 108 | CT.18 | LEU 176 | 45.51x51 | Hydrophobic |
| PRO 108 | CT.18 | LEU 176 | 45.51x51 | VdWContact |
| LYS 109 | CT.19 | TYR 90 | 2.63x63 | Hydrophobic |
| LYS 109 | CT.19 | TYR 90 | 2.63x63 | VdWContact |
| LYS 109 | CT.19 | LEU 91 | 2.64x64 | HBDonor |
| LYS 109 | CT.19 | LEU 91 | 2.64x64 | Hydrophobic |
| LYS 109 | CT.19 | LEU 91 | 2.64x64 | VdWContact |
| LYS 109 | CT.19 | GLU 174 | - | Cationic |
| LYS 109 | CT.19 | GLU 174 | - | Hydrophobic |
| LYS 109 | CT.19 | GLU 174 | - | VdWContact |
| PRO 111 | CT.21 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 111 | CT.21 | TRP 87 | 2.60x60 | VdWContact |
| PRO 111 | CT.21 | PHE 109 | 3.32x32 | Hydrophobic |
| PRO 111 | CT.21 | PHE 109 | 3.32x32 | VdWContact |
| PRO 111 | CT.21 | PHE 110 | 3.33x33 | VdWContact |
| PRO 111 | CT.21 | PHE 283 | 7.43x42 | Hydrophobic |
