Predicted complex interactions
CCL22_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 108
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TRP 87 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | THR 106 | 3.29x29 | HBDonor |
| GLY 1 | NTc.Cm35 | THR 106 | 3.29x29 | VdWContact |
| GLY 1 | NTc.Cm35 | PHE 110 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 38 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | GLU 279 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 283 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm34 | PHE 283 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | PHE 110 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | ASN 192 | 5.39x40 | HBDonor |
| TYR 3 | NTc.Cm33 | ASN 192 | 5.39x40 | VdWContact |
| TYR 3 | NTc.Cm33 | THR 195 | 5.42x43 | HBAcceptor |
| TYR 3 | NTc.Cm33 | THR 195 | 5.42x43 | Hydrophobic |
| TYR 3 | NTc.Cm33 | THR 195 | 5.42x43 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 247 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 247 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | ILE 251 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 275 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 275 | 7.35x34 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 279 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 279 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 279 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 279 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | TYR 38 | 1.39x39 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TRP 87 | 2.60x60 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TYR 90 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 91 | 2.64x64 | Hydrophobic |
| ASN 6 | NTc.Cm30 | CYS 175 | 45.50x50 | HBDonor |
| ASN 6 | NTc.Cm30 | CYS 175 | 45.50x50 | VdWContact |
| MET 7 | NTc.Cm29 | GLU 254 | 6.58x58 | Hydrophobic |
| MET 7 | NTc.Cm29 | ARG 272 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | LEU 275 | 7.35x34 | Hydrophobic |
| MET 7 | NTc.Cm29 | LEU 275 | 7.35x34 | VdWContact |
| GLU 8 | NTc.Cm28 | LEU 176 | 45.51x51 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ARG 272 | 7.32x31 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 272 | 7.32x31 | VdWContact |
| ASP 9 | NTc.Cm27 | VAL 27 | 1.28x28 | Hydrophobic |
| ASP 9 | NTc.Cm27 | VAL 27 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | GLU 174 | - | HBDonor |
| ASP 9 | NTc.Cm27 | GLU 174 | - | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 272 | 7.32x31 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 272 | 7.32x31 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 272 | 7.32x31 | VdWContact |
| VAL 11 | NTc.Cm25 | ALA 20 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | TYR 22 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | TYR 22 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASP 260 | 6.64x64 | Cationic |
| ARG 14 | NTc.Cm22 | ASP 260 | 6.64x64 | HBDonor |
| ARG 14 | NTc.Cm22 | ASP 260 | 6.64x64 | VdWContact |
| ARG 14 | NTc.Cm22 | ARG 268 | 7.28x27 | VdWContact |
| VAL 17 | NTc.Cm19 | ASP 15 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | ASP 15 | - | VdWContact |
| VAL 17 | NTc.Cm19 | ALA 18 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | ALA 18 | - | VdWContact |
| ARG 18 | NTc.Cm18 | ASP 15 | - | HBDonor |
| ARG 18 | NTc.Cm18 | ASP 15 | - | VdWContact |
| TYR 19 | NTc.Cm17 | PHE 12 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 12 | - | VdWContact |
| TYR 19 | NTc.Cm17 | GLU 13 | - | VdWContact |
| TYR 19 | NTc.Cm17 | TYR 14 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ASP 15 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | ASP 15 | - | VdWContact |
| LEU 21 | NTc.Cm15 | PHE 12 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | PHE 12 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 14 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | PHE 12 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | PHE 12 | - | VdWContact |
| ARG 24 | NTc.Cm12 | PHE 4 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | VAL 8 | - | VdWContact |
| VAL 25 | NTc.Cm11 | THR 9 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | THR 9 | - | VdWContact |
| VAL 25 | NTc.Cm11 | PHE 12 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| SER 33 | NTc.Cm3 | GLU 172 | - | HBDonor |
| SER 33 | NTc.Cm3 | GLU 172 | - | VdWContact |
| ASP 34 | NTc.Cm2 | LYS 171 | - | HBAcceptor |
| ASP 34 | NTc.Cm2 | LYS 171 | - | VdWContact |
| ASP 34 | NTc.Cm2 | GLU 172 | - | HBDonor |
| ASP 34 | NTc.Cm2 | GLU 172 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | GLU 172 | - | VdWContact |
| SER 35 | NTc.Cm1 | LYS 171 | - | VdWContact |
| SER 35 | NTc.Cm1 | GLU 172 | - | HBDonor |
| SER 35 | NTc.Cm1 | GLU 174 | - | HBDonor |
| SER 35 | NTc.Cm1 | GLU 174 | - | VdWContact |
| ARG 38 | cxb1.1 | GLU 185 | 5.32x33 | Cationic |
| ARG 38 | cxb1.1 | GLU 185 | 5.32x33 | HBDonor |
| ARG 38 | cxb1.1 | GLU 185 | 5.32x33 | VdWContact |
| VAL 42 | cxb1.7 | ALA 20 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 14 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 14 | - | VdWContact |
| ARG 47 | cxb1.15 | GLU 10 | - | HBDonor |
| ARG 47 | cxb1.15 | GLU 10 | - | VdWContact |
| ARG 47 | cxb1.15 | TYR 14 | - | VdWContact |
| LYS 49 | B1.1 | TYR 14 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 14 | - | VdWContact |
| LYS 49 | B1.1 | ASP 16 | - | Cationic |
| LYS 49 | B1.1 | ASP 16 | - | VdWContact |
| GLU 50 | B1.2 | GLU 19 | - | VdWContact |
| GLU 50 | B1.2 | ALA 20 | - | HBAcceptor |
| GLU 50 | B1.2 | ALA 20 | - | Hydrophobic |
| GLU 50 | B1.2 | ALA 20 | - | VdWContact |
| ILE 51 | B1.3 | TYR 14 | - | Hydrophobic |
| ILE 51 | B1.3 | ALA 18 | - | Hydrophobic |
| CYS 52 | B1.4 | ALA 18 | - | HBDonor |
| CYS 52 | B1.4 | ALA 18 | - | VdWContact |
