Predicted complex interactions
CCL25_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 127
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | GLU 94 | - | Cationic |
| GLN 1 | NTc.Cm29 | GLU 94 | - | VdWContact |
| PHE 4 | NTc.Cm26 | TYR 22 | - | VdWContact |
| PHE 4 | NTc.Cm26 | GLY 24 | 1.25x25 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 27 | 1.28x28 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 27 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 28 | 1.29x29 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 28 | 1.29x29 | VdWContact |
| ASP 6 | NTc.Cm24 | ALA 20 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | ALA 20 | - | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 21 | - | VdWContact |
| ASP 6 | NTc.Cm24 | TYR 22 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 21 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 21 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 21 | - | VdWContact |
| CYS 7 | NTc.Cm23 | ILE 23 | 1.24x24 | Hydrophobic |
| CYS 7 | NTc.Cm23 | ILE 23 | 1.24x24 | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 21 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 21 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ILE 23 | 1.24x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | ILE 23 | 1.24x24 | VdWContact |
| LEU 9 | NTc.Cm21 | ARG 268 | 7.28x27 | HBAcceptor |
| LEU 9 | NTc.Cm21 | ARG 268 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | ARG 268 | 7.28x27 | VdWContact |
| HIS 12 | NTc.Cm18 | ASP 15 | - | HBAcceptor |
| HIS 12 | NTc.Cm18 | ASP 15 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ASP 15 | - | VdWContact |
| HIS 12 | NTc.Cm18 | ALA 18 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ALA 18 | - | VdWContact |
| VAL 19 | NTc.Cm11 | PHE 12 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | PHE 12 | - | VdWContact |
| VAL 19 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 14 | - | VdWContact |
| ARG 22 | NTc.Cm8 | VAL 8 | - | HBDonor |
| ARG 22 | NTc.Cm8 | VAL 8 | - | VdWContact |
| ARG 22 | NTc.Cm8 | THR 9 | - | VdWContact |
| GLU 30 | CX.1 | LYS 171 | - | Anionic |
| GLU 30 | CX.1 | LYS 171 | - | HBAcceptor |
| GLU 30 | CX.1 | LYS 171 | - | VdWContact |
| VAL 31 | CX.5 | LEU 176 | 45.51x51 | Hydrophobic |
| SER 32 | cxb1.1 | GLU 174 | - | VdWContact |
| GLY 33 | cxb1.2 | GLU 174 | - | HBDonor |
| GLY 33 | cxb1.2 | GLU 174 | - | VdWContact |
| GLY 33 | cxb1.2 | ARG 272 | 7.32x31 | HBAcceptor |
| GLY 33 | cxb1.2 | ARG 272 | 7.32x31 | VdWContact |
| SER 34 | cxb1.5 | ARG 272 | 7.32x31 | HBAcceptor |
| SER 34 | cxb1.5 | ARG 272 | 7.32x31 | VdWContact |
| ILE 41 | cxb1.16 | ALA 20 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 14 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 14 | - | VdWContact |
| LYS 46 | B1.5 | THR 9 | - | HBDonor |
| LYS 46 | B1.5 | THR 9 | - | VdWContact |
| LYS 46 | B1.5 | GLU 10 | - | Cationic |
| LYS 46 | B1.5 | GLU 10 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 14 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 16 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 16 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 16 | - | VdWContact |
| ARG 49 | b1b2.1 | GLU 19 | - | Cationic |
| ARG 49 | b1b2.1 | GLU 19 | - | VdWContact |
| LYS 50 | b1b2.2 | GLU 19 | - | HBDonor |
| LYS 50 | b1b2.2 | GLU 19 | - | VdWContact |
| LYS 50 | b1b2.2 | ALA 20 | - | HBAcceptor |
| LYS 50 | b1b2.2 | ALA 20 | - | Hydrophobic |
| LYS 50 | b1b2.2 | ALA 20 | - | VdWContact |
| VAL 51 | b1b2.3 | TYR 14 | - | Hydrophobic |
| CYS 52 | b1b2.4 | ALA 18 | - | HBDonor |
| CYS 52 | b1b2.4 | ALA 18 | - | VdWContact |
| LYS 56 | b1b2.9 | GLU 185 | 5.32x33 | Cationic |
| SER 113 | CT.23 | GLU 94 | - | VdWContact |
| LYS 114 | CT.24 | GLU 172 | - | Cationic |
| LYS 114 | CT.24 | GLU 172 | - | HBDonor |
| LYS 114 | CT.24 | GLU 172 | - | VdWContact |
| ARG 115 | CT.25 | HIS 89 | 2.62x62 | HBDonor |
| ARG 115 | CT.25 | HIS 89 | 2.62x62 | VdWContact |
| ARG 115 | CT.25 | TYR 90 | 2.63x63 | VdWContact |
| ARG 115 | CT.25 | LEU 91 | 2.64x64 | HBDonor |
| ARG 115 | CT.25 | LEU 91 | 2.64x64 | VdWContact |
| ARG 115 | CT.25 | ILE 92 | 2.65x65 | VdWContact |
| ARG 115 | CT.25 | ASN 93 | 2.66x66 | VdWContact |
| ARG 115 | CT.25 | GLY 96 | - | HBDonor |
| ARG 115 | CT.25 | GLY 96 | - | VdWContact |
| ASN 116 | CT.26 | TYR 90 | 2.63x63 | Hydrophobic |
| ASN 116 | CT.26 | TYR 90 | 2.63x63 | VdWContact |
| ASN 116 | CT.26 | GLU 174 | - | HBDonor |
| ASN 116 | CT.26 | GLU 174 | - | VdWContact |
| VAL 117 | CT.27 | VAL 27 | 1.28x28 | Hydrophobic |
| VAL 117 | CT.27 | VAL 27 | 1.28x28 | VdWContact |
| VAL 117 | CT.27 | GLY 30 | 1.31x31 | VdWContact |
| VAL 117 | CT.27 | THR 31 | 1.32x32 | VdWContact |
| VAL 117 | CT.27 | LEU 34 | 1.35x35 | Hydrophobic |
| VAL 117 | CT.27 | LEU 34 | 1.35x35 | VdWContact |
| VAL 117 | CT.27 | LEU 91 | 2.64x64 | Hydrophobic |
| VAL 117 | CT.27 | LEU 91 | 2.64x64 | VdWContact |
| SER 118 | CT.28 | GLU 279 | 7.39x38 | HBDonor |
| SER 118 | CT.28 | GLU 279 | 7.39x38 | VdWContact |
| LEU 119 | CT.29 | TYR 38 | 1.39x39 | Hydrophobic |
| LEU 119 | CT.29 | TRP 87 | 2.60x60 | Hydrophobic |
| LEU 119 | CT.29 | TRP 87 | 2.60x60 | VdWContact |
| LEU 119 | CT.29 | PHE 109 | 3.32x32 | Hydrophobic |
| LEU 119 | CT.29 | GLU 279 | 7.39x38 | HBDonor |
| LEU 119 | CT.29 | GLU 279 | 7.39x38 | VdWContact |
| LEU 119 | CT.29 | PHE 283 | 7.43x42 | Hydrophobic |
| LEU 120 | CT.30 | PHE 109 | 3.32x32 | Hydrophobic |
| LEU 120 | CT.30 | PHE 110 | 3.33x33 | Hydrophobic |
| LEU 120 | CT.30 | TYR 247 | 6.51x51 | Hydrophobic |
| LEU 120 | CT.30 | TYR 247 | 6.51x51 | VdWContact |
| LEU 120 | CT.30 | PHE 283 | 7.43x42 | Hydrophobic |
| ILE 121 | CT.31 | ARG 272 | 7.32x31 | Hydrophobic |
| ILE 121 | CT.31 | LEU 275 | 7.35x34 | Hydrophobic |
| ILE 121 | CT.31 | LEU 275 | 7.35x34 | VdWContact |
| SER 122 | CT.32 | CYS 175 | 45.50x50 | VdWContact |
| SER 122 | CT.32 | LEU 176 | 45.51x51 | VdWContact |
| ALA 123 | CT.33 | TYR 179 | - | VdWContact |
| ASN 124 | CT.34 | ARG 191 | 5.38x39 | HBAcceptor |
| ASN 124 | CT.34 | ARG 191 | 5.38x39 | VdWContact |
| ASN 124 | CT.34 | ASN 192 | 5.39x40 | HBDonor |
| ASN 124 | CT.34 | ASN 192 | 5.39x40 | VdWContact |
| SER 125 | CT.35 | LEU 176 | 45.51x51 | VdWContact |
| GLY 126 | CT.36 | GLY 177 | 45.52x52 | VdWContact |
| GLY 126 | CT.36 | TYR 179 | - | VdWContact |
| LEU 127 | CT.37 | GLN 184 | 5.31x32 | VdWContact |
| LEU 127 | CT.37 | GLU 185 | 5.32x33 | Hydrophobic |
| LEU 127 | CT.37 | GLU 185 | 5.32x33 | VdWContact |
| LEU 127 | CT.37 | PRO 188 | 5.35x36 | Hydrophobic |
| LEU 127 | CT.37 | LEU 258 | 6.62x62 | Hydrophobic |
| LEU 127 | CT.37 | LEU 258 | 6.62x62 | VdWContact |
