Predicted complex interactions
CCL7_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 102 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TRP 102 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 124 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | ASP 179 | 4.60x61 | Cationic |
| GLN 1 | NTc.Cm33 | CYS 195 | 45.50x50 | VdWContact |
| GLN 1 | NTc.Cm33 | HIS 196 | 45.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | ALA 197 | 45.52x52 | HBDonor |
| GLN 1 | NTc.Cm33 | ALA 197 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 124 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 302 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm31 | LEU 270 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm31 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm31 | LEU 294 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm31 | GLU 298 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm31 | GLU 298 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm30 | GLN 295 | 7.36x35 | HBAcceptor |
| GLY 4 | NTc.Cm30 | GLN 295 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 298 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 298 | 7.39x38 | VdWContact |
| ILE 5 | NTc.Cm29 | LEU 49 | 1.35x35 | Hydrophobic |
| ILE 5 | NTc.Cm29 | LEU 49 | 1.35x35 | VdWContact |
| ILE 5 | NTc.Cm29 | TYR 53 | 1.39x39 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TRP 102 | 2.60x60 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TRP 102 | 2.60x60 | VdWContact |
| ILE 5 | NTc.Cm29 | VAL 106 | 2.64x64 | Hydrophobic |
| ILE 5 | NTc.Cm29 | VAL 106 | 2.64x64 | VdWContact |
| THR 7 | NTc.Cm27 | LYS 38 | 1.24x24 | Hydrophobic |
| THR 7 | NTc.Cm27 | VAL 41 | 1.27x27 | Hydrophobic |
| THR 7 | NTc.Cm27 | VAL 42 | 1.28x28 | Hydrophobic |
| THR 7 | NTc.Cm27 | ASP 291 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm27 | GLN 295 | 7.36x35 | HBAcceptor |
| THR 7 | NTc.Cm27 | GLN 295 | 7.36x35 | VdWContact |
| SER 8 | NTc.Cm26 | LYS 38 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | LYS 38 | 1.24x24 | HBAcceptor |
| THR 9 | NTc.Cm25 | LYS 38 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | VAL 42 | 1.28x28 | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 35 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 35 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 36 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 36 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 36 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 36 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LYS 38 | 1.24x24 | Anionic |
| TYR 13 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 36 | - | VdWContact |
| TYR 13 | NTc.Cm21 | LEU 276 | 6.61x61 | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 284 | 7.25x24 | Hydrophobic |
| TYR 13 | NTc.Cm21 | SER 287 | 7.28x27 | VdWContact |
| ARG 14 | NTc.Cm20 | MET 34 | - | Hydrophobic |
| PHE 15 | NTc.Cm19 | MET 34 | - | VdWContact |
| ILE 16 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ILE 16 | NTc.Cm18 | VAL 31 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | VAL 31 | - | VdWContact |
| LYS 18 | NTc.Cm16 | TYR 27 | - | HBDonor |
| LYS 18 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 24 | - | Hydrophobic |
| ILE 20 | NTc.Cm14 | TYR 24 | - | VdWContact |
| PRO 21 | NTc.Cm13 | TYR 24 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 24 | - | VdWContact |
| ARG 24 | NTc.Cm10 | SER 21 | - | HBDonor |
| ARG 24 | NTc.Cm10 | SER 21 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 24 | - | CationPi |
| ARG 24 | NTc.Cm10 | TYR 24 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | TYR 24 | - | VdWContact |
| SER 33 | NTc.Cm1 | LYS 207 | 5.35x36 | HBAcceptor |
| SER 33 | NTc.Cm1 | LYS 207 | 5.35x36 | VdWContact |
| HIS 35 | CX.5 | HIS 196 | 45.51x51 | Hydrophobic |
| HIS 35 | CX.5 | HIS 196 | 45.51x51 | VdWContact |
| CYS 36 | cxb1.1 | LYS 207 | 5.35x36 | HBAcceptor |
| CYS 36 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| PRO 37 | cxb1.2 | LEU 276 | 6.61x61 | Hydrophobic |
| PRO 37 | cxb1.2 | ASP 277 | 6.62x62 | VdWContact |
| ARG 38 | cxb1.5 | GLN 279 | 6.64x64 | VdWContact |
| ILE 42 | cxb1.10 | LEU 35 | - | Hydrophobic |
| ILE 42 | cxb1.10 | LEU 35 | - | VdWContact |
| THR 45 | cxb1.15 | LEU 28 | - | Hydrophobic |
| LEU 47 | B1.1 | TYR 25 | - | Hydrophobic |
| LEU 47 | B1.1 | TYR 25 | - | VdWContact |
| LEU 47 | B1.1 | LEU 28 | - | Hydrophobic |
| LYS 49 | B1.3 | LEU 28 | - | Hydrophobic |
| LYS 49 | B1.3 | ASP 29 | - | Cationic |
| LYS 49 | B1.3 | ASP 29 | - | HBDonor |
| LYS 49 | B1.3 | ASP 29 | - | VdWContact |
| GLU 50 | B1.4 | LEU 35 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 35 | - | VdWContact |
| GLU 50 | B1.4 | ARG 37 | - | Anionic |
| ILE 51 | B1.5 | LEU 28 | - | Hydrophobic |
| ILE 51 | B1.5 | LEU 28 | - | VdWContact |
| ILE 51 | B1.5 | VAL 31 | - | Hydrophobic |
| CYS 52 | B1.6 | MET 34 | - | Hydrophobic |
| CYS 52 | B1.6 | LEU 35 | - | VdWContact |
