Predicted complex interactions
CCL4_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 86
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TRP 87 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TRP 87 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm33 | THR 106 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 283 | 7.43x42 | Hydrophobic |
| MET 3 | NTc.Cm31 | ASN 192 | 5.39x40 | VdWContact |
| MET 3 | NTc.Cm31 | ILE 251 | 6.55x55 | Hydrophobic |
| MET 3 | NTc.Cm31 | ILE 251 | 6.55x55 | VdWContact |
| MET 3 | NTc.Cm31 | GLU 254 | 6.58x58 | Hydrophobic |
| MET 3 | NTc.Cm31 | ARG 272 | 7.32x31 | HBAcceptor |
| MET 3 | NTc.Cm31 | ARG 272 | 7.32x31 | VdWContact |
| MET 3 | NTc.Cm31 | LEU 275 | 7.35x34 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 275 | 7.35x34 | VdWContact |
| MET 3 | NTc.Cm31 | GLU 279 | 7.39x38 | HBDonor |
| MET 3 | NTc.Cm31 | GLU 279 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm30 | LEU 34 | 1.35x35 | VdWContact |
| GLY 4 | NTc.Cm30 | ARG 272 | 7.32x31 | HBAcceptor |
| GLY 4 | NTc.Cm30 | ARG 272 | 7.32x31 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 279 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 279 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | TYR 90 | 2.63x63 | VdWContact |
| SER 5 | NTc.Cm29 | LEU 91 | 2.64x64 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 90 | 2.63x63 | HBAcceptor |
| ASP 6 | NTc.Cm28 | TYR 90 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm28 | LEU 176 | 45.51x51 | Hydrophobic |
| ASP 6 | NTc.Cm28 | LEU 176 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm28 | ARG 272 | 7.32x31 | HBAcceptor |
| ASP 6 | NTc.Cm28 | ARG 272 | 7.32x31 | VdWContact |
| PRO 7 | NTc.Cm27 | VAL 27 | 1.28x28 | Hydrophobic |
| PRO 7 | NTc.Cm27 | VAL 27 | 1.28x28 | VdWContact |
| PRO 7 | NTc.Cm27 | ARG 272 | 7.32x31 | VdWContact |
| THR 9 | NTc.Cm25 | ILE 23 | 1.24x24 | HBAcceptor |
| THR 9 | NTc.Cm25 | ILE 23 | 1.24x24 | VdWContact |
| ALA 10 | NTc.Cm24 | CYS 21 | - | VdWContact |
| ALA 10 | NTc.Cm24 | TYR 22 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | TYR 22 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 21 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 21 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 21 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 21 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 21 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ARG 268 | 7.28x27 | PiCation |
| PHE 13 | NTc.Cm21 | ARG 268 | 7.28x27 | VdWContact |
| SER 14 | NTc.Cm20 | LEU 17 | - | HBDonor |
| SER 14 | NTc.Cm20 | LEU 17 | - | VdWContact |
| SER 14 | NTc.Cm20 | ALA 18 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PHE 12 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | GLU 13 | - | Cationic |
| ARG 18 | NTc.Cm16 | GLU 13 | - | HBDonor |
| ARG 18 | NTc.Cm16 | GLU 13 | - | VdWContact |
| LEU 20 | NTc.Cm14 | PHE 12 | - | Hydrophobic |
| LEU 20 | NTc.Cm14 | PHE 12 | - | VdWContact |
| LEU 20 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | PHE 12 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | PHE 12 | - | VdWContact |
| ASN 23 | NTc.Cm11 | THR 9 | - | VdWContact |
| PHE 24 | NTc.Cm10 | THR 9 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | THR 9 | - | VdWContact |
| PHE 24 | NTc.Cm10 | PHE 12 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | PHE 12 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 14 | - | Hydrophobic |
| SER 32 | NTc.Cm2 | GLU 174 | - | HBDonor |
| SER 32 | NTc.Cm2 | GLU 174 | - | VdWContact |
| LEU 34 | CX.1 | LEU 176 | 45.51x51 | Hydrophobic |
| LEU 34 | CX.1 | LEU 176 | 45.51x51 | VdWContact |
| VAL 41 | cxb1.8 | ALA 20 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 14 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 14 | - | VdWContact |
| ARG 46 | cxb1.16 | GLU 10 | - | HBDonor |
| ARG 46 | cxb1.16 | GLU 10 | - | VdWContact |
| ARG 46 | cxb1.16 | TYR 14 | - | VdWContact |
| LYS 48 | B1.2 | ASP 16 | - | Cationic |
| LYS 48 | B1.2 | GLU 19 | - | Cationic |
| LYS 48 | B1.2 | GLU 19 | - | HBDonor |
| LYS 48 | B1.2 | GLU 19 | - | VdWContact |
| GLN 49 | B1.3 | GLU 19 | - | VdWContact |
| GLN 49 | B1.3 | ALA 20 | - | HBAcceptor |
| GLN 49 | B1.3 | ALA 20 | - | Hydrophobic |
| GLN 49 | B1.3 | ALA 20 | - | VdWContact |
| VAL 50 | B1.4 | TYR 14 | - | Hydrophobic |
| VAL 50 | B1.4 | ALA 18 | - | Hydrophobic |
| CYS 51 | B1.5 | ALA 18 | - | HBDonor |
| CYS 51 | B1.5 | ALA 18 | - | VdWContact |
| CYS 51 | B1.5 | ALA 20 | - | VdWContact |
