Predicted complex interactions
CCL8_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 92
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 87 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TRP 87 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | THR 106 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | CYS 175 | 45.50x50 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 283 | 7.43x42 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 247 | 6.51x51 | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 247 | 6.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | ILE 251 | 6.55x55 | Hydrophobic |
| ASP 3 | NTc.Cm31 | ILE 251 | 6.55x55 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 272 | 7.32x31 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 272 | 7.32x31 | VdWContact |
| ASP 3 | NTc.Cm31 | LEU 275 | 7.35x34 | Hydrophobic |
| ASP 3 | NTc.Cm31 | LEU 275 | 7.35x34 | VdWContact |
| ASP 3 | NTc.Cm31 | GLU 279 | 7.39x38 | HBDonor |
| ASP 3 | NTc.Cm31 | GLU 279 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm30 | LEU 34 | 1.35x35 | VdWContact |
| SER 4 | NTc.Cm30 | TYR 38 | 1.39x39 | VdWContact |
| SER 4 | NTc.Cm30 | ARG 272 | 7.32x31 | HBAcceptor |
| SER 4 | NTc.Cm30 | ARG 272 | 7.32x31 | VdWContact |
| SER 4 | NTc.Cm30 | SER 276 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm30 | GLU 279 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm30 | GLU 279 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm29 | TYR 90 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm29 | TYR 90 | 2.63x63 | VdWContact |
| VAL 5 | NTc.Cm29 | LEU 91 | 2.64x64 | Hydrophobic |
| VAL 5 | NTc.Cm29 | ARG 272 | 7.32x31 | VdWContact |
| SER 6 | NTc.Cm28 | VAL 27 | 1.28x28 | VdWContact |
| SER 6 | NTc.Cm28 | ARG 272 | 7.32x31 | HBAcceptor |
| SER 6 | NTc.Cm28 | ARG 272 | 7.32x31 | VdWContact |
| ILE 7 | NTc.Cm27 | TYR 90 | 2.63x63 | Hydrophobic |
| ILE 7 | NTc.Cm27 | TYR 90 | 2.63x63 | VdWContact |
| ILE 7 | NTc.Cm27 | GLU 174 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | GLU 174 | - | VdWContact |
| PRO 8 | NTc.Cm26 | VAL 27 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | VAL 27 | 1.28x28 | VdWContact |
| THR 10 | NTc.Cm24 | ALA 20 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | CYS 21 | - | VdWContact |
| THR 10 | NTc.Cm24 | TYR 22 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | TYR 22 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 21 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 21 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 21 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 21 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 21 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ILE 23 | 1.24x24 | Hydrophobic |
| PHE 13 | NTc.Cm21 | ARG 268 | 7.28x27 | PiCation |
| PHE 13 | NTc.Cm21 | ARG 268 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | LEU 17 | - | HBDonor |
| ASN 14 | NTc.Cm20 | LEU 17 | - | VdWContact |
| ILE 16 | NTc.Cm18 | PHE 12 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | ALA 18 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | PHE 12 | - | CationPi |
| ARG 18 | NTc.Cm16 | PHE 12 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | PHE 12 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLU 13 | - | VdWContact |
| ILE 20 | NTc.Cm14 | PHE 12 | - | Hydrophobic |
| ILE 20 | NTc.Cm14 | PHE 12 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | PHE 12 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | PHE 12 | - | VdWContact |
| ARG 24 | NTc.Cm10 | VAL 8 | - | HBDonor |
| ARG 24 | NTc.Cm10 | VAL 8 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | VAL 8 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLU 10 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 10 | - | VdWContact |
| ARG 24 | NTc.Cm10 | PHE 12 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 14 | - | VdWContact |
| ILE 34 | CX.1 | LYS 171 | - | Hydrophobic |
| ILE 34 | CX.1 | LYS 171 | - | VdWContact |
| GLN 35 | CX.5 | GLU 174 | - | HBDonor |
| GLN 35 | CX.5 | GLU 174 | - | VdWContact |
| GLN 35 | CX.5 | LEU 176 | 45.51x51 | Hydrophobic |
| GLN 35 | CX.5 | LEU 176 | 45.51x51 | VdWContact |
| ILE 42 | cxb1.10 | ALA 20 | - | Hydrophobic |
| ILE 42 | cxb1.10 | ALA 20 | - | VdWContact |
| THR 45 | cxb1.15 | TYR 14 | - | Hydrophobic |
| THR 45 | cxb1.15 | TYR 14 | - | VdWContact |
| LYS 49 | B1.3 | TYR 14 | - | Hydrophobic |
| LYS 49 | B1.3 | ASP 16 | - | Cationic |
| GLU 50 | B1.4 | GLU 19 | - | VdWContact |
| GLU 50 | B1.4 | ALA 20 | - | HBAcceptor |
| GLU 50 | B1.4 | ALA 20 | - | Hydrophobic |
| GLU 50 | B1.4 | ALA 20 | - | VdWContact |
| VAL 51 | B1.5 | TYR 14 | - | Hydrophobic |
| VAL 51 | B1.5 | TYR 14 | - | VdWContact |
| VAL 51 | B1.5 | ALA 18 | - | Hydrophobic |
| CYS 52 | B1.6 | ALA 18 | - | HBDonor |
| CYS 52 | B1.6 | ALA 18 | - | VdWContact |
| CYS 52 | B1.6 | ALA 20 | - | VdWContact |
