Predicted complex interactions
CXCL1_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | PHE 110 | 3.33x33 | Hydrophobic |
| ALA 1 | NTc.Cm42 | PHE 110 | 3.33x33 | VdWContact |
| ALA 1 | NTc.Cm42 | ARG 191 | 5.38x39 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 247 | 6.51x51 | VdWContact |
| SER 2 | NTc.Cm41 | ARG 272 | 7.32x31 | HBAcceptor |
| SER 2 | NTc.Cm41 | ARG 272 | 7.32x31 | VdWContact |
| SER 2 | NTc.Cm41 | LEU 275 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm40 | TYR 38 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TYR 38 | 1.39x39 | VdWContact |
| VAL 3 | NTc.Cm40 | GLU 279 | 7.39x38 | Hydrophobic |
| VAL 3 | NTc.Cm40 | GLU 279 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | TRP 87 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm39 | TRP 87 | 2.60x60 | VdWContact |
| ALA 4 | NTc.Cm39 | TYR 90 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | CYS 175 | 45.50x50 | VdWContact |
| THR 5 | NTc.Cm38 | LEU 176 | 45.51x51 | Hydrophobic |
| THR 5 | NTc.Cm38 | LEU 176 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm37 | LYS 257 | 6.61x61 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 272 | 7.32x31 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 272 | 7.32x31 | VdWContact |
| LEU 7 | NTc.Cm36 | LEU 34 | 1.35x35 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LEU 34 | 1.35x35 | VdWContact |
| LEU 7 | NTc.Cm36 | LEU 91 | 2.64x64 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LEU 91 | 2.64x64 | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 272 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm35 | VAL 27 | 1.28x28 | Hydrophobic |
| ARG 8 | NTc.Cm35 | VAL 27 | 1.28x28 | VdWContact |
| ARG 8 | NTc.Cm35 | TYR 90 | 2.63x63 | CationPi |
| ARG 8 | NTc.Cm35 | TYR 90 | 2.63x63 | HBDonor |
| ARG 8 | NTc.Cm35 | TYR 90 | 2.63x63 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 91 | 2.64x64 | VdWContact |
| ARG 8 | NTc.Cm35 | ASN 93 | 2.66x66 | HBDonor |
| ARG 8 | NTc.Cm35 | ASN 93 | 2.66x66 | VdWContact |
| GLN 10 | NTc.Cm33 | TYR 22 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | TYR 22 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | TYR 22 | - | VdWContact |
| GLN 10 | NTc.Cm33 | ILE 23 | 1.24x24 | HBAcceptor |
| GLN 10 | NTc.Cm33 | ILE 23 | 1.24x24 | VdWContact |
| GLN 10 | NTc.Cm33 | VAL 27 | 1.28x28 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 21 | - | HBDonor |
| LEU 12 | NTc.Cm31 | CYS 21 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 21 | - | VdWContact |
| LEU 12 | NTc.Cm31 | ILE 23 | 1.24x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | ARG 268 | 7.28x27 | Hydrophobic |
| LEU 12 | NTc.Cm31 | ARG 268 | 7.28x27 | VdWContact |
| GLN 13 | NTc.Cm30 | CYS 21 | - | HBAcceptor |
| GLN 13 | NTc.Cm30 | CYS 21 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | CYS 21 | - | VdWContact |
| GLN 13 | NTc.Cm30 | ARG 268 | 7.28x27 | VdWContact |
| LEU 15 | NTc.Cm28 | TYR 14 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | ALA 18 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | ALA 18 | - | VdWContact |
| LEU 15 | NTc.Cm28 | ALA 20 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | ALA 20 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 14 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 14 | - | VdWContact |
| HIS 19 | NTc.Cm24 | THR 9 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | THR 9 | - | VdWContact |
| PRO 20 | NTc.Cm23 | THR 9 | - | Hydrophobic |
| PRO 31 | NTc.Cm12 | GLU 172 | - | VdWContact |
| GLY 32 | NTc.Cm11 | GLU 172 | - | VdWContact |
| GLY 32 | NTc.Cm11 | GLU 174 | - | HBDonor |
| GLY 32 | NTc.Cm11 | GLU 174 | - | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 90 | 2.63x63 | VdWContact |
| PRO 33 | NTc.Cm10 | GLU 94 | - | VdWContact |
| PRO 33 | NTc.Cm10 | ASN 173 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | ASN 173 | - | VdWContact |
| PRO 33 | NTc.Cm10 | GLU 174 | - | VdWContact |
| HIS 34 | NTc.Cm9 | TYR 90 | 2.63x63 | HBDonor |
| HIS 34 | NTc.Cm9 | TYR 90 | 2.63x63 | Hydrophobic |
| HIS 34 | NTc.Cm9 | TYR 90 | 2.63x63 | VdWContact |
| HIS 34 | NTc.Cm9 | GLU 174 | - | HBDonor |
| HIS 34 | NTc.Cm9 | GLU 174 | - | VdWContact |
| CYS 35 | NTc.Cm8 | GLU 174 | - | HBDonor |
| CYS 35 | NTc.Cm8 | GLU 174 | - | VdWContact |
| ALA 36 | NTc.Cm7 | GLU 174 | - | VdWContact |
| ALA 36 | NTc.Cm7 | LEU 176 | 45.51x51 | Hydrophobic |
| ALA 36 | NTc.Cm7 | LEU 176 | 45.51x51 | VdWContact |
| ILE 41 | NTc.Cm2 | TYR 22 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | TYR 22 | - | VdWContact |
| ARG 48 | cxb1.5 | GLU 19 | - | Cationic |
| LYS 49 | cxb1.6 | TYR 22 | - | Hydrophobic |
| LYS 49 | cxb1.6 | TYR 22 | - | VdWContact |
| ALA 50 | cxb1.8 | ALA 20 | - | Hydrophobic |
| ALA 50 | cxb1.8 | ALA 20 | - | VdWContact |
| CYS 51 | cxb1.10 | ALA 20 | - | Hydrophobic |
| CYS 51 | cxb1.10 | ALA 20 | - | VdWContact |
| ILE 58 | B1.3 | PHE 12 | - | Hydrophobic |
| ILE 58 | B1.3 | PHE 12 | - | VdWContact |
| LYS 65 | b1b2.7 | PHE 4 | - | Hydrophobic |
| LYS 65 | b1b2.7 | PHE 4 | - | VdWContact |
