Predicted complex interactions
CXCL12_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CXCL12_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm29 | TRP 87 | 2.60x60 | Hydrophobic |
| LYS 1 | NTc.Cm29 | TRP 87 | 2.60x60 | VdWContact |
| LYS 1 | NTc.Cm29 | THR 106 | 3.29x29 | HBDonor |
| LYS 1 | NTc.Cm29 | THR 106 | 3.29x29 | VdWContact |
| LYS 1 | NTc.Cm29 | PHE 110 | 3.33x33 | VdWContact |
| LYS 1 | NTc.Cm29 | CYS 175 | 45.50x50 | HBDonor |
| LYS 1 | NTc.Cm29 | CYS 175 | 45.50x50 | Hydrophobic |
| LYS 1 | NTc.Cm29 | CYS 175 | 45.50x50 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLU 279 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 283 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLU 254 | 6.58x58 | Hydrophobic |
| VAL 3 | NTc.Cm27 | LEU 275 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm27 | LEU 275 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm27 | GLU 279 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm27 | GLU 279 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm26 | GLU 279 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm26 | GLU 279 | 7.39x38 | VdWContact |
| LEU 5 | NTc.Cm25 | LEU 34 | 1.35x35 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TRP 87 | 2.60x60 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 90 | 2.63x63 | Hydrophobic |
| LEU 5 | NTc.Cm25 | LEU 91 | 2.64x64 | Hydrophobic |
| LEU 5 | NTc.Cm25 | LEU 91 | 2.64x64 | VdWContact |
| TYR 7 | NTc.Cm23 | ARG 272 | 7.32x31 | HBAcceptor |
| TYR 7 | NTc.Cm23 | ARG 272 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm22 | TYR 90 | 2.63x63 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 91 | 2.64x64 | VdWContact |
| ARG 8 | NTc.Cm22 | GLU 174 | - | Cationic |
| ARG 8 | NTc.Cm22 | GLU 174 | - | VdWContact |
| ARG 8 | NTc.Cm22 | ARG 272 | 7.32x31 | VdWContact |
| PRO 10 | NTc.Cm20 | CYS 21 | - | HBAcceptor |
| PRO 10 | NTc.Cm20 | CYS 21 | - | VdWContact |
| PRO 10 | NTc.Cm20 | TYR 22 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | LEU 17 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | LEU 17 | - | VdWContact |
| GLU 15 | NTc.Cm15 | TYR 14 | - | Hydrophobic |
| GLU 15 | NTc.Cm15 | TYR 14 | - | VdWContact |
| GLU 15 | NTc.Cm15 | ALA 18 | - | Hydrophobic |
| HIS 17 | NTc.Cm13 | PHE 12 | - | Hydrophobic |
| VAL 18 | NTc.Cm12 | TYR 14 | - | Hydrophobic |
| VAL 18 | NTc.Cm12 | TYR 14 | - | VdWContact |
| ASN 22 | NTc.Cm8 | TYR 14 | - | VdWContact |
| PRO 32 | CX.5 | GLU 94 | - | Hydrophobic |
| ASN 33 | cxb1.1 | GLU 94 | - | VdWContact |
| ASN 33 | cxb1.1 | GLU 174 | - | Hydrophobic |
| ALA 35 | cxb1.5 | GLU 172 | - | HBDonor |
| ALA 35 | cxb1.5 | GLU 172 | - | VdWContact |
| VAL 39 | cxb1.11 | ALA 20 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TYR 14 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TYR 14 | - | VdWContact |
| ARG 47 | B1.5 | ASP 16 | - | Cationic |
| ARG 47 | B1.5 | ASP 16 | - | VdWContact |
| GLN 48 | B1.6 | GLU 19 | - | VdWContact |
| GLN 48 | B1.6 | ALA 20 | - | HBAcceptor |
| GLN 48 | B1.6 | ALA 20 | - | Hydrophobic |
| GLN 48 | B1.6 | ALA 20 | - | VdWContact |
| VAL 49 | B1.7 | TYR 14 | - | Hydrophobic |
| VAL 49 | B1.7 | ALA 18 | - | Hydrophobic |
| VAL 49 | B1.7 | ALA 18 | - | VdWContact |
| CYS 50 | b1b2.4 | ALA 18 | - | HBDonor |
| CYS 50 | b1b2.4 | ALA 18 | - | VdWContact |
| CYS 50 | b1b2.4 | ALA 20 | - | VdWContact |
