Predicted complex interactions
CXCL4_HUMAN + CX3CR1
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CX3CR1 View partner entry
- Partner description
- UniProt: P49238; Gene: cx3c1_human; Family: Chemokine
- Interactions detected
- 104
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 16 | NTc.Cm25 | GLU 172 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | GLU 172 | - | VdWContact |
| SER 17 | NTc.Cm24 | LYS 171 | - | VdWContact |
| SER 17 | NTc.Cm24 | GLU 172 | - | HBDonor |
| SER 17 | NTc.Cm24 | GLU 172 | - | VdWContact |
| GLN 18 | NTc.Cm23 | LYS 171 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | LYS 171 | - | VdWContact |
| GLN 18 | NTc.Cm23 | GLU 172 | - | HBAcceptor |
| GLN 18 | NTc.Cm23 | GLU 172 | - | HBDonor |
| GLN 18 | NTc.Cm23 | GLU 172 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | GLU 172 | - | VdWContact |
| GLN 18 | NTc.Cm23 | GLU 174 | - | VdWContact |
| VAL 19 | NTc.Cm22 | GLU 174 | - | VdWContact |
| VAL 19 | NTc.Cm22 | LEU 176 | 45.51x51 | VdWContact |
| ARG 20 | NTc.Cm21 | TYR 90 | 2.63x63 | Hydrophobic |
| ARG 20 | NTc.Cm21 | TYR 90 | 2.63x63 | VdWContact |
| ARG 20 | NTc.Cm21 | LEU 97 | - | HBDonor |
| ARG 20 | NTc.Cm21 | LEU 97 | - | VdWContact |
| ARG 20 | NTc.Cm21 | CYS 102 | 3.25x25 | Cationic |
| ARG 20 | NTc.Cm21 | GLN 170 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ASN 173 | - | HBDonor |
| ARG 20 | NTc.Cm21 | ASN 173 | - | VdWContact |
| ARG 20 | NTc.Cm21 | GLU 174 | - | HBDonor |
| ARG 20 | NTc.Cm21 | GLU 174 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | GLU 174 | - | VdWContact |
| ARG 20 | NTc.Cm21 | CYS 175 | 45.50x50 | Cationic |
| ARG 20 | NTc.Cm21 | CYS 175 | 45.50x50 | Hydrophobic |
| ARG 20 | NTc.Cm21 | CYS 175 | 45.50x50 | VdWContact |
| ARG 20 | NTc.Cm21 | LEU 176 | 45.51x51 | VdWContact |
| PRO 21 | NTc.Cm20 | LEU 176 | 45.51x51 | Hydrophobic |
| PRO 21 | NTc.Cm20 | LEU 176 | 45.51x51 | VdWContact |
| PRO 21 | NTc.Cm20 | ARG 272 | 7.32x31 | HBAcceptor |
| PRO 21 | NTc.Cm20 | ARG 272 | 7.32x31 | VdWContact |
| ARG 22 | NTc.Cm19 | TRP 87 | 2.60x60 | VdWContact |
| ARG 22 | NTc.Cm19 | TYR 90 | 2.63x63 | CationPi |
| ARG 22 | NTc.Cm19 | TYR 90 | 2.63x63 | Hydrophobic |
| ARG 22 | NTc.Cm19 | TYR 90 | 2.63x63 | VdWContact |
| ARG 22 | NTc.Cm19 | LEU 97 | - | VdWContact |
| ARG 22 | NTc.Cm19 | CYS 175 | 45.50x50 | Cationic |
| ARG 22 | NTc.Cm19 | CYS 175 | 45.50x50 | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 90 | 2.63x63 | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 90 | 2.63x63 | PiStacking |
| HIS 23 | NTc.Cm18 | TYR 90 | 2.63x63 | VdWContact |
| HIS 23 | NTc.Cm18 | GLU 174 | - | HBDonor |
| HIS 23 | NTc.Cm18 | GLU 174 | - | VdWContact |
| ILE 24 | NTc.Cm17 | ARG 272 | 7.32x31 | HBAcceptor |
| ILE 24 | NTc.Cm17 | ARG 272 | 7.32x31 | VdWContact |
| THR 25 | NTc.Cm16 | ILE 23 | 1.24x24 | VdWContact |
| THR 25 | NTc.Cm16 | VAL 27 | 1.28x28 | Hydrophobic |
| THR 25 | NTc.Cm16 | VAL 27 | 1.28x28 | VdWContact |
| THR 25 | NTc.Cm16 | ARG 272 | 7.32x31 | Hydrophobic |
| THR 25 | NTc.Cm16 | ARG 272 | 7.32x31 | VdWContact |
| SER 26 | NTc.Cm15 | ILE 23 | 1.24x24 | HBAcceptor |
| SER 26 | NTc.Cm15 | ILE 23 | 1.24x24 | VdWContact |
| SER 26 | NTc.Cm15 | VAL 27 | 1.28x28 | VdWContact |
| GLU 28 | NTc.Cm13 | ALA 20 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | ALA 20 | - | VdWContact |
| GLU 28 | NTc.Cm13 | CYS 21 | - | VdWContact |
| GLU 28 | NTc.Cm13 | TYR 22 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | TYR 22 | - | VdWContact |
| VAL 29 | NTc.Cm12 | ALA 20 | - | VdWContact |
| ILE 30 | NTc.Cm11 | ALA 20 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | ALA 20 | - | VdWContact |
| LYS 31 | NTc.Cm10 | ALA 18 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | ALA 18 | - | VdWContact |
| GLY 33 | NTc.Cm8 | TYR 14 | - | VdWContact |
| PRO 34 | NTc.Cm7 | TYR 14 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | TYR 14 | - | VdWContact |
| THR 44 | cxb1.1 | TYR 22 | - | Hydrophobic |
| THR 44 | cxb1.1 | TYR 22 | - | VdWContact |
| THR 44 | cxb1.1 | GLY 24 | 1.25x25 | VdWContact |
| THR 44 | cxb1.1 | VAL 27 | 1.28x28 | Hydrophobic |
| THR 44 | cxb1.1 | VAL 27 | 1.28x28 | VdWContact |
| LEU 45 | cxb1.2 | VAL 27 | 1.28x28 | VdWContact |
| LYS 46 | cxb1.5 | VAL 27 | 1.28x28 | VdWContact |
| LYS 46 | cxb1.5 | VAL 28 | 1.29x29 | VdWContact |
| LYS 46 | cxb1.5 | THR 31 | 1.32x32 | VdWContact |
| LYS 46 | cxb1.5 | LEU 34 | 1.35x35 | VdWContact |
| LYS 46 | cxb1.5 | LEU 91 | 2.64x64 | Hydrophobic |
| LYS 46 | cxb1.5 | LEU 91 | 2.64x64 | VdWContact |
| ASN 47 | cxb1.6 | GLU 94 | - | VdWContact |
| GLY 48 | cxb1.8 | VAL 28 | 1.29x29 | VdWContact |
| ARG 49 | cxb1.10 | GLU 94 | - | Cationic |
| ARG 49 | cxb1.10 | GLU 94 | - | HBDonor |
| ARG 49 | cxb1.10 | GLU 94 | - | VdWContact |
| LYS 50 | cxb1.11 | TYR 22 | - | CationPi |
| LYS 50 | cxb1.11 | TYR 22 | - | Hydrophobic |
| LYS 50 | cxb1.11 | TYR 22 | - | VdWContact |
| LEU 59 | B1.6 | LEU 176 | 45.51x51 | Hydrophobic |
| LEU 59 | B1.6 | LEU 176 | 45.51x51 | VdWContact |
| LEU 59 | B1.6 | GLY 177 | 45.52x52 | VdWContact |
| LYS 62 | b1b2.6 | GLU 181 | - | HBDonor |
| LYS 62 | b1b2.6 | GLU 181 | - | VdWContact |
| LYS 62 | b1b2.6 | GLN 184 | 5.31x32 | VdWContact |
| LYS 62 | b1b2.6 | GLU 185 | 5.32x33 | Cationic |
| LYS 62 | b1b2.6 | GLU 185 | 5.32x33 | HBDonor |
| LYS 62 | b1b2.6 | GLU 185 | 5.32x33 | VdWContact |
| LYS 66 | b1b2.10 | LEU 258 | 6.62x62 | HBDonor |
| LYS 66 | b1b2.10 | LEU 258 | 6.62x62 | VdWContact |
| LYS 66 | b1b2.10 | ASP 260 | 6.64x64 | Cationic |
| LYS 66 | b1b2.10 | ASP 260 | 6.64x64 | HBDonor |
| LYS 66 | b1b2.10 | ASP 260 | 6.64x64 | VdWContact |
| LEU 67 | b1b2.12 | ARG 268 | 7.28x27 | VdWContact |
| SER 70 | b1b2.16 | ALA 18 | - | VdWContact |
