Predicted complex interactions
CX3CL1_HUMAN + ACKR2
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | TYR 124 | 3.32x32 | HBAcceptor |
| GLN 1 | NTc.Cm37 | TYR 124 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm37 | ASP 179 | 4.60x61 | Cationic |
| GLN 1 | NTc.Cm37 | ASP 179 | 4.60x61 | HBDonor |
| GLN 1 | NTc.Cm37 | ASP 179 | 4.60x61 | VdWContact |
| GLN 1 | NTc.Cm37 | ALA 197 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm37 | PHE 199 | - | VdWContact |
| GLN 1 | NTc.Cm37 | GLN 214 | 5.42x43 | HBDonor |
| GLN 1 | NTc.Cm37 | GLN 214 | 5.42x43 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 53 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 53 | 1.39x39 | VdWContact |
| HIS 2 | NTc.Cm36 | TRP 102 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TRP 102 | 2.60x60 | PiStacking |
| HIS 2 | NTc.Cm36 | TRP 102 | 2.60x60 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 124 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 298 | 7.39x38 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 298 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | PHE 302 | 7.43x42 | Hydrophobic |
| HIS 2 | NTc.Cm36 | PHE 302 | 7.43x42 | VdWContact |
| HIS 3 | NTc.Cm35 | LEU 270 | 6.55x55 | Hydrophobic |
| HIS 3 | NTc.Cm35 | LEU 294 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | LEU 294 | 7.35x34 | VdWContact |
| HIS 3 | NTc.Cm35 | GLU 298 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 298 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | GLU 298 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm34 | GLU 298 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | TYR 53 | 1.39x39 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 102 | 2.60x60 | VdWContact |
| VAL 5 | NTc.Cm33 | VAL 106 | 2.64x64 | Hydrophobic |
| VAL 5 | NTc.Cm33 | VAL 106 | 2.64x64 | VdWContact |
| LYS 7 | NTc.Cm31 | VAL 42 | 1.28x28 | Hydrophobic |
| LYS 7 | NTc.Cm31 | SER 105 | 2.63x63 | HBDonor |
| LYS 7 | NTc.Cm31 | SER 105 | 2.63x63 | VdWContact |
| LYS 7 | NTc.Cm31 | VAL 106 | 2.64x64 | HBDonor |
| LYS 7 | NTc.Cm31 | VAL 106 | 2.64x64 | VdWContact |
| LYS 7 | NTc.Cm31 | TRP 108 | 2.66x66 | VdWContact |
| LYS 7 | NTc.Cm31 | ASN 194 | - | VdWContact |
| CYS 8 | NTc.Cm30 | LYS 38 | 1.24x24 | VdWContact |
| ASN 9 | NTc.Cm29 | ARG 37 | - | VdWContact |
| ASN 9 | NTc.Cm29 | LYS 38 | 1.24x24 | HBAcceptor |
| ASN 9 | NTc.Cm29 | LYS 38 | 1.24x24 | VdWContact |
| ASN 9 | NTc.Cm29 | ASP 39 | 1.25x25 | HBDonor |
| ASN 9 | NTc.Cm29 | ASP 39 | 1.25x25 | VdWContact |
| ILE 10 | NTc.Cm28 | LEU 35 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | CYS 36 | - | VdWContact |
| ILE 10 | NTc.Cm28 | ARG 37 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | LEU 35 | - | VdWContact |
| THR 11 | NTc.Cm27 | CYS 36 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 36 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 36 | - | VdWContact |
| THR 11 | NTc.Cm27 | LYS 38 | 1.24x24 | Hydrophobic |
| THR 11 | NTc.Cm27 | LYS 38 | 1.24x24 | VdWContact |
| CYS 12 | NTc.Cm26 | MET 34 | - | VdWContact |
| SER 13 | NTc.Cm25 | MET 34 | - | HBDonor |
| SER 13 | NTc.Cm25 | MET 34 | - | VdWContact |
| LYS 14 | NTc.Cm24 | MET 34 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | MET 34 | - | VdWContact |
| MET 15 | NTc.Cm23 | MET 34 | - | VdWContact |
| THR 16 | NTc.Cm22 | MET 34 | - | VdWContact |
| LYS 18 | NTc.Cm20 | TYR 24 | - | VdWContact |
| ILE 19 | NTc.Cm19 | TYR 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | TYR 24 | - | VdWContact |
| ILE 19 | NTc.Cm19 | LEU 28 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | TYR 24 | - | VdWContact |
| LEU 23 | NTc.Cm15 | TYR 24 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | TYR 25 | - | Hydrophobic |
| GLN 29 | NTc.Cm9 | ASN 188 | - | HBAcceptor |
| GLN 29 | NTc.Cm9 | ASN 188 | - | VdWContact |
| ASN 30 | NTc.Cm8 | ASN 188 | - | VdWContact |
| ALA 32 | NTc.Cm6 | HIS 186 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | HIS 196 | 45.51x51 | Hydrophobic |
| SER 33 | NTc.Cm5 | HIS 196 | 45.51x51 | VdWContact |
| THR 43 | cxb1.1 | TYR 25 | - | Hydrophobic |
| THR 43 | cxb1.1 | TYR 25 | - | VdWContact |
| GLN 45 | cxb1.5 | TYR 25 | - | Hydrophobic |
| GLN 45 | cxb1.5 | TYR 25 | - | VdWContact |
| ARG 47 | cxb1.8 | TYR 25 | - | VdWContact |
| ARG 47 | cxb1.8 | ASP 29 | - | Cationic |
| ARG 47 | cxb1.8 | ASP 29 | - | HBDonor |
| ARG 47 | cxb1.8 | ASP 29 | - | VdWContact |
| LEU 48 | cxb1.10 | LEU 35 | - | Hydrophobic |
| LEU 48 | cxb1.10 | LEU 35 | - | VdWContact |
| PHE 49 | cxb1.11 | LEU 28 | - | Hydrophobic |
| PHE 49 | cxb1.11 | LEU 28 | - | VdWContact |
| PHE 49 | cxb1.11 | VAL 31 | - | Hydrophobic |
| PHE 49 | cxb1.11 | ALA 32 | - | Hydrophobic |
| CYS 50 | cxb1.14 | MET 34 | - | Hydrophobic |
| CYS 50 | cxb1.14 | LEU 35 | - | VdWContact |
