Predicted complex interactions
CXCL1_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TRP 102 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TRP 102 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm42 | ASP 179 | 4.60x61 | Cationic |
| SER 2 | NTc.Cm41 | TYR 53 | 1.39x39 | HBAcceptor |
| SER 2 | NTc.Cm41 | GLU 298 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm41 | GLU 298 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm40 | LEU 270 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm40 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm40 | LEU 294 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm40 | GLU 298 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm40 | GLU 298 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | LEU 49 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | GLN 295 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | GLN 295 | 7.36x35 | VdWContact |
| ALA 4 | NTc.Cm39 | GLU 298 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm39 | GLU 298 | 7.39x38 | VdWContact |
| THR 5 | NTc.Cm38 | VAL 106 | 2.64x64 | Hydrophobic |
| THR 5 | NTc.Cm38 | VAL 106 | 2.64x64 | VdWContact |
| GLU 6 | NTc.Cm37 | LYS 207 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 211 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 211 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 211 | 5.39x40 | VdWContact |
| LEU 7 | NTc.Cm36 | VAL 42 | 1.28x28 | Hydrophobic |
| ARG 8 | NTc.Cm35 | LYS 38 | 1.24x24 | Hydrophobic |
| ARG 8 | NTc.Cm35 | LYS 38 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm35 | HIS 273 | 6.58x58 | Hydrophobic |
| ARG 8 | NTc.Cm35 | HIS 273 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | SER 287 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm35 | SER 287 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 290 | 7.31x30 | HBDonor |
| ARG 8 | NTc.Cm35 | LEU 290 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 291 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 291 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 291 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | LEU 35 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | LEU 35 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 36 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 36 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 36 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 284 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 284 | 7.25x24 | VdWContact |
| GLN 13 | NTc.Cm30 | MET 34 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | LEU 28 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | VAL 31 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | VAL 31 | - | VdWContact |
| LEU 15 | NTc.Cm28 | MET 34 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | MET 34 | - | VdWContact |
| GLY 17 | NTc.Cm26 | TYR 24 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 24 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 24 | - | VdWContact |
| ILE 18 | NTc.Cm25 | LEU 28 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | LEU 28 | - | VdWContact |
| HIS 19 | NTc.Cm24 | TYR 24 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | TYR 24 | - | PiStacking |
| HIS 19 | NTc.Cm24 | TYR 24 | - | VdWContact |
| ASN 22 | NTc.Cm21 | TYR 25 | - | VdWContact |
| ASN 22 | NTc.Cm21 | LEU 28 | - | VdWContact |
| PRO 33 | NTc.Cm10 | HIS 196 | 45.51x51 | Hydrophobic |
| PRO 33 | NTc.Cm10 | HIS 196 | 45.51x51 | VdWContact |
| PRO 33 | NTc.Cm10 | ALA 197 | 45.52x52 | Hydrophobic |
| PRO 33 | NTc.Cm10 | ALA 197 | 45.52x52 | VdWContact |
| PRO 33 | NTc.Cm10 | ASP 198 | - | VdWContact |
| PRO 33 | NTc.Cm10 | LYS 207 | 5.35x36 | HBAcceptor |
| PRO 33 | NTc.Cm10 | LYS 207 | 5.35x36 | VdWContact |
| HIS 34 | NTc.Cm9 | HIS 196 | 45.51x51 | Hydrophobic |
| HIS 34 | NTc.Cm9 | HIS 196 | 45.51x51 | VdWContact |
| ALA 36 | NTc.Cm7 | THR 204 | 5.32x33 | Hydrophobic |
| ALA 36 | NTc.Cm7 | THR 204 | 5.32x33 | VdWContact |
| ALA 36 | NTc.Cm7 | LYS 207 | 5.35x36 | Hydrophobic |
| GLN 37 | NTc.Cm6 | GLN 279 | 6.64x64 | VdWContact |
| ILE 41 | NTc.Cm2 | LEU 35 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | LEU 35 | - | VdWContact |
| LEU 44 | CX.4 | LEU 28 | - | Hydrophobic |
| ARG 48 | cxb1.5 | ASP 29 | - | Cationic |
| ARG 48 | cxb1.5 | ASP 29 | - | HBDonor |
| ARG 48 | cxb1.5 | ASP 29 | - | VdWContact |
| ARG 48 | cxb1.5 | ALA 32 | - | Hydrophobic |
| LYS 49 | cxb1.6 | ALA 32 | - | VdWContact |
| LYS 49 | cxb1.6 | LEU 35 | - | Hydrophobic |
| LYS 49 | cxb1.6 | LEU 35 | - | VdWContact |
| CYS 51 | cxb1.10 | MET 34 | - | Hydrophobic |
