Predicted complex interactions
CCL17_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 90
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | GLU 291 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| ARG 2 | NTc.Cm31 | GLU 118 | 3.33x33 | Cationic |
| ARG 2 | NTc.Cm31 | GLU 118 | 3.33x33 | HBDonor |
| ARG 2 | NTc.Cm31 | GLU 118 | 3.33x33 | VdWContact |
| ARG 2 | NTc.Cm31 | PHE 121 | 3.36x36 | CationPi |
| ARG 2 | NTc.Cm31 | PHE 121 | 3.36x36 | VdWContact |
| ARG 2 | NTc.Cm31 | PHE 171 | 4.60x61 | Hydrophobic |
| ARG 2 | NTc.Cm31 | ARG 203 | 5.39x40 | HBAcceptor |
| ARG 2 | NTc.Cm31 | ARG 203 | 5.39x40 | VdWContact |
| ARG 2 | NTc.Cm31 | PRO 206 | 5.42x43 | VdWContact |
| ARG 2 | NTc.Cm31 | TYR 258 | 6.51x51 | HBDonor |
| ARG 2 | NTc.Cm31 | TYR 258 | 6.51x51 | Hydrophobic |
| ARG 2 | NTc.Cm31 | TYR 258 | 6.51x51 | VdWContact |
| ARG 2 | NTc.Cm31 | LEU 262 | 6.55x55 | Hydrophobic |
| GLY 3 | NTc.Cm30 | LEU 287 | 7.35x34 | VdWContact |
| THR 4 | NTc.Cm29 | VAL 186 | - | Hydrophobic |
| THR 4 | NTc.Cm29 | ARG 199 | 5.35x36 | HBAcceptor |
| THR 4 | NTc.Cm29 | ARG 199 | 5.35x36 | VdWContact |
| ASN 5 | NTc.Cm28 | ARG 269 | 6.62x62 | VdWContact |
| VAL 6 | NTc.Cm27 | TYR 178 | - | Hydrophobic |
| VAL 6 | NTc.Cm27 | TYR 178 | - | VdWContact |
| VAL 6 | NTc.Cm27 | PRO 180 | - | Hydrophobic |
| VAL 6 | NTc.Cm27 | VAL 186 | - | Hydrophobic |
| VAL 6 | NTc.Cm27 | TYR 188 | 45.51x51 | Hydrophobic |
| VAL 6 | NTc.Cm27 | TYR 188 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm25 | LEU 32 | - | HBAcceptor |
| ARG 8 | NTc.Cm25 | LEU 32 | - | VdWContact |
| ARG 8 | NTc.Cm25 | ASN 182 | - | VdWContact |
| ARG 8 | NTc.Cm25 | SER 183 | - | HBAcceptor |
| ARG 8 | NTc.Cm25 | SER 183 | - | VdWContact |
| GLU 9 | NTc.Cm24 | PRO 29 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | PRO 29 | - | VdWContact |
| GLU 9 | NTc.Cm24 | CYS 30 | - | VdWContact |
| GLU 9 | NTc.Cm24 | LEU 32 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 30 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 30 | - | VdWContact |
| CYS 10 | NTc.Cm23 | ARG 280 | 7.28x27 | Anionic |
| CYS 10 | NTc.Cm23 | ARG 280 | 7.28x27 | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 30 | - | VdWContact |
| LEU 12 | NTc.Cm21 | GLU 275 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | SER 276 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 277 | 7.25x24 | VdWContact |
| GLU 13 | NTc.Cm20 | TYR 27 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | PRO 21 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | PRO 21 | - | VdWContact |
| PHE 15 | NTc.Cm18 | PRO 22 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | PRO 22 | - | VdWContact |
| PHE 15 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | TYR 27 | - | PiStacking |
| PHE 15 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ALA 18 | NTc.Cm15 | PHE 17 | - | Hydrophobic |
| ALA 18 | NTc.Cm15 | PHE 17 | - | VdWContact |
| PRO 20 | NTc.Cm13 | PRO 21 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | PRO 21 | - | VdWContact |
| LEU 21 | NTc.Cm12 | LEU 15 | - | Hydrophobic |
| LYS 23 | NTc.Cm10 | THR 18 | - | VdWContact |
| LYS 23 | NTc.Cm10 | MET 20 | - | Hydrophobic |
| TYR 28 | NTc.Cm5 | ASN 181 | - | Hydrophobic |
| GLN 29 | NTc.Cm4 | ASN 181 | - | VdWContact |
| GLU 32 | NTc.Cm1 | THR 195 | 5.31x32 | HBAcceptor |
| GLU 32 | NTc.Cm1 | THR 195 | 5.31x32 | VdWContact |
| GLU 32 | NTc.Cm1 | ALA 196 | 5.32x33 | VdWContact |
| ASP 33 | CX.1 | TYR 188 | 45.51x51 | VdWContact |
| ASP 33 | CX.1 | ARG 199 | 5.35x36 | Anionic |
| ASP 33 | CX.1 | ARG 199 | 5.35x36 | HBAcceptor |
| ASP 33 | CX.1 | ARG 199 | 5.35x36 | VdWContact |
| ASP 33 | CX.1 | ARG 269 | 6.62x62 | Anionic |
| ASP 33 | CX.1 | ARG 269 | 6.62x62 | VdWContact |
| ASP 33 | CX.1 | ARG 280 | 7.28x27 | HBAcceptor |
| ASP 33 | CX.1 | ARG 280 | 7.28x27 | VdWContact |
| SER 35 | cxb1.1 | GLN 271 | 6.64x64 | VdWContact |
| SER 35 | cxb1.1 | GLU 275 | - | HBDonor |
| SER 35 | cxb1.1 | GLU 275 | - | VdWContact |
| VAL 40 | cxb1.8 | PRO 29 | - | Hydrophobic |
| GLN 45 | cxb1.16 | MET 20 | - | VdWContact |
| ARG 47 | B1.2 | MET 20 | - | VdWContact |
| ARG 47 | B1.2 | ALA 23 | - | VdWContact |
| ALA 48 | B1.3 | PRO 29 | - | Hydrophobic |
| ILE 49 | B1.4 | PRO 21 | - | Hydrophobic |
| CYS 50 | B1.5 | TYR 27 | - | HBDonor |
| CYS 50 | B1.5 | TYR 27 | - | VdWContact |
| CYS 50 | B1.5 | PRO 29 | - | VdWContact |
| ARG 57 | b1b2.12 | ASP 14 | - | Cationic |
| ARG 57 | b1b2.12 | ASP 14 | - | VdWContact |
| ASN 60 | b1b2.16 | TRP 10 | - | Hydrophobic |
| ASN 60 | b1b2.16 | TRP 10 | - | VdWContact |
| LYS 63 | B2.3 | TRP 10 | - | Hydrophobic |
| TYR 64 | B2.4 | TRP 10 | - | Hydrophobic |
| TYR 64 | B2.4 | TRP 10 | - | VdWContact |
