Predicted complex interactions
CCL2_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TYR 188 | 45.51x51 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 188 | 45.51x51 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 188 | 45.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 189 | 45.52x52 | Cationic |
| GLN 1 | NTc.Cm33 | ARG 199 | 5.35x36 | VdWContact |
| GLN 1 | NTc.Cm33 | ARG 269 | 6.62x62 | HBAcceptor |
| GLN 1 | NTc.Cm33 | ARG 269 | 6.62x62 | VdWContact |
| PRO 2 | NTc.Cm32 | VAL 186 | - | Hydrophobic |
| PRO 2 | NTc.Cm32 | VAL 186 | - | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 188 | 45.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 188 | 45.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 99 | 2.64x64 | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 99 | 2.64x64 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 199 | 5.35x36 | Anionic |
| ALA 4 | NTc.Cm30 | VAL 186 | - | Hydrophobic |
| ALA 4 | NTc.Cm30 | VAL 186 | - | VdWContact |
| ILE 5 | NTc.Cm29 | THR 34 | - | HBAcceptor |
| ILE 5 | NTc.Cm29 | THR 34 | - | VdWContact |
| ILE 5 | NTc.Cm29 | PRO 180 | - | Hydrophobic |
| ILE 5 | NTc.Cm29 | PRO 180 | - | VdWContact |
| ILE 5 | NTc.Cm29 | SER 183 | - | VdWContact |
| ILE 5 | NTc.Cm29 | SER 184 | - | VdWContact |
| ILE 5 | NTc.Cm29 | VAL 186 | - | Hydrophobic |
| ILE 5 | NTc.Cm29 | VAL 186 | - | VdWContact |
| ASN 6 | NTc.Cm28 | THR 34 | - | HBAcceptor |
| ASN 6 | NTc.Cm28 | THR 34 | - | VdWContact |
| ASN 6 | NTc.Cm28 | GLU 35 | - | Hydrophobic |
| ASN 6 | NTc.Cm28 | GLU 35 | - | VdWContact |
| ASN 6 | NTc.Cm28 | LYS 99 | 2.64x64 | HBDonor |
| ASN 6 | NTc.Cm28 | LYS 99 | 2.64x64 | VdWContact |
| ALA 7 | NTc.Cm27 | SER 183 | - | VdWContact |
| PRO 8 | NTc.Cm26 | MET 31 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | MET 31 | - | VdWContact |
| PRO 8 | NTc.Cm26 | LEU 32 | - | VdWContact |
| VAL 9 | NTc.Cm25 | LEU 32 | - | HBAcceptor |
| VAL 9 | NTc.Cm25 | LEU 32 | - | HBDonor |
| VAL 9 | NTc.Cm25 | LEU 32 | - | Hydrophobic |
| VAL 9 | NTc.Cm25 | LEU 32 | - | VdWContact |
| THR 10 | NTc.Cm24 | PRO 29 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 29 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 30 | - | VdWContact |
| THR 10 | NTc.Cm24 | MET 31 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | MET 31 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 30 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 30 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 30 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LEU 32 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 30 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 30 | - | VdWContact |
| TYR 13 | NTc.Cm21 | LEU 32 | - | VdWContact |
| TYR 13 | NTc.Cm21 | GLU 275 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | GLU 275 | - | VdWContact |
| TYR 13 | NTc.Cm21 | ARG 280 | 7.28x27 | HBAcceptor |
| TYR 13 | NTc.Cm21 | ARG 280 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ASP 26 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASP 26 | - | VdWContact |
| ASN 14 | NTc.Cm20 | TYR 27 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | GLU 275 | - | HBDonor |
| ASN 14 | NTc.Cm20 | GLU 275 | - | VdWContact |
| PHE 15 | NTc.Cm19 | TYR 27 | - | VdWContact |
| THR 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PRO 21 | - | Hydrophobic |
| ILE 20 | NTc.Cm14 | PRO 21 | - | Hydrophobic |
| ILE 20 | NTc.Cm14 | PRO 21 | - | VdWContact |
| ARG 24 | NTc.Cm10 | THR 18 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLY 19 | - | VdWContact |
| ARG 24 | NTc.Cm10 | MET 20 | - | Hydrophobic |
| SER 34 | CX.1 | TYR 178 | - | HBDonor |
| SER 34 | CX.1 | TYR 178 | - | VdWContact |
| SER 34 | CX.1 | TYR 188 | 45.51x51 | VdWContact |
| LYS 35 | CX.5 | TYR 178 | - | Hydrophobic |
| LYS 35 | CX.5 | PRO 180 | - | Hydrophobic |
| LYS 35 | CX.5 | PRO 180 | - | VdWContact |
| LYS 35 | CX.5 | SER 183 | - | VdWContact |
| PRO 37 | cxb1.2 | ALA 196 | 5.32x33 | Hydrophobic |
| PRO 37 | cxb1.2 | ARG 280 | 7.28x27 | VdWContact |
| ILE 42 | cxb1.10 | PRO 29 | - | Hydrophobic |
| ILE 42 | cxb1.10 | PRO 29 | - | VdWContact |
| THR 45 | cxb1.15 | MET 20 | - | Hydrophobic |
| THR 45 | cxb1.15 | MET 20 | - | VdWContact |
| ILE 46 | cxb1.16 | MET 20 | - | Hydrophobic |
| VAL 47 | B1.1 | MET 20 | - | Hydrophobic |
| VAL 47 | B1.1 | MET 20 | - | VdWContact |
| LYS 49 | B1.3 | ALA 23 | - | Hydrophobic |
| LYS 49 | B1.3 | ALA 23 | - | VdWContact |
| GLU 50 | B1.4 | PRO 29 | - | Hydrophobic |
| GLU 50 | B1.4 | PRO 29 | - | VdWContact |
| ILE 51 | B1.5 | TYR 27 | - | Hydrophobic |
| CYS 52 | B1.6 | TYR 27 | - | HBDonor |
| CYS 52 | B1.6 | TYR 27 | - | VdWContact |
| CYS 52 | B1.6 | PRO 29 | - | VdWContact |
