Predicted complex interactions
CCL21_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 96
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | ARG 199 | 5.35x36 | HBAcceptor |
| SER 1 | NTc.Cm30 | ARG 199 | 5.35x36 | VdWContact |
| ASP 2 | NTc.Cm29 | LYS 117 | 3.32x32 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 175 | 4.64x65 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 199 | 5.35x36 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 199 | 5.35x36 | HBAcceptor |
| ASP 2 | NTc.Cm29 | ARG 199 | 5.35x36 | VdWContact |
| ASP 2 | NTc.Cm29 | TYR 258 | 6.51x51 | VdWContact |
| ASP 2 | NTc.Cm29 | LEU 262 | 6.55x55 | Hydrophobic |
| ASP 2 | NTc.Cm29 | LEU 287 | 7.35x34 | Hydrophobic |
| ASP 2 | NTc.Cm29 | LEU 287 | 7.35x34 | VdWContact |
| GLY 3 | NTc.Cm28 | ARG 269 | 6.62x62 | HBAcceptor |
| GLY 3 | NTc.Cm28 | ARG 269 | 6.62x62 | VdWContact |
| GLY 3 | NTc.Cm28 | LEU 287 | 7.35x34 | VdWContact |
| ALA 5 | NTc.Cm26 | PRO 180 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | PRO 180 | - | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 186 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | VAL 186 | - | VdWContact |
| ALA 5 | NTc.Cm26 | TYR 188 | 45.51x51 | Hydrophobic |
| GLN 6 | NTc.Cm25 | LEU 32 | - | VdWContact |
| GLN 6 | NTc.Cm25 | PRO 180 | - | Hydrophobic |
| GLN 6 | NTc.Cm25 | PRO 180 | - | VdWContact |
| GLN 6 | NTc.Cm25 | ARG 280 | 7.28x27 | HBAcceptor |
| GLN 6 | NTc.Cm25 | ARG 280 | 7.28x27 | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 29 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | CYS 30 | - | VdWContact |
| ASP 7 | NTc.Cm24 | MET 31 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LEU 32 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | LEU 32 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 30 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 30 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 30 | - | VdWContact |
| CYS 8 | NTc.Cm23 | ARG 280 | 7.28x27 | Anionic |
| CYS 8 | NTc.Cm23 | ARG 280 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 30 | - | VdWContact |
| LEU 10 | NTc.Cm21 | GLU 275 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | GLU 275 | - | VdWContact |
| LYS 11 | NTc.Cm20 | ASP 26 | - | Cationic |
| LYS 11 | NTc.Cm20 | ASP 26 | - | HBDonor |
| LYS 11 | NTc.Cm20 | ASP 26 | - | Hydrophobic |
| LYS 11 | NTc.Cm20 | ASP 26 | - | VdWContact |
| LYS 11 | NTc.Cm20 | TYR 27 | - | Hydrophobic |
| TYR 12 | NTc.Cm19 | TYR 27 | - | VdWContact |
| GLN 14 | NTc.Cm17 | TYR 27 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | PRO 21 | - | Hydrophobic |
| LYS 16 | NTc.Cm15 | PHE 12 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | MET 20 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PRO 21 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PRO 21 | - | VdWContact |
| PRO 18 | NTc.Cm13 | PHE 12 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | PHE 12 | - | VdWContact |
| PRO 18 | NTc.Cm13 | PHE 17 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | PHE 17 | - | VdWContact |
| LYS 20 | NTc.Cm11 | ASP 13 | - | Cationic |
| LYS 20 | NTc.Cm11 | ASP 13 | - | HBDonor |
| LYS 20 | NTc.Cm11 | ASP 13 | - | VdWContact |
| LYS 20 | NTc.Cm11 | PHE 17 | - | VdWContact |
| VAL 21 | NTc.Cm10 | GLY 19 | - | VdWContact |
| VAL 21 | NTc.Cm10 | MET 20 | - | Hydrophobic |
| ARG 26 | NTc.Cm5 | ASN 182 | - | HBDonor |
| ARG 26 | NTc.Cm5 | ASN 182 | - | VdWContact |
| PRO 30 | NTc.Cm1 | ASN 193 | - | VdWContact |
| LEU 32 | CX.5 | TYR 178 | - | Hydrophobic |
| LEU 32 | CX.5 | TYR 178 | - | VdWContact |
| LEU 32 | CX.5 | TYR 188 | 45.51x51 | Hydrophobic |
| LEU 32 | CX.5 | TYR 188 | 45.51x51 | VdWContact |
| LEU 32 | CX.5 | VAL 190 | - | Hydrophobic |
| LEU 32 | CX.5 | VAL 190 | - | VdWContact |
| GLY 33 | cxb1.1 | ARG 269 | 6.62x62 | VdWContact |
| GLY 33 | cxb1.1 | ARG 280 | 7.28x27 | HBAcceptor |
| GLY 33 | cxb1.1 | ARG 280 | 7.28x27 | VdWContact |
| SER 35 | cxb1.5 | GLU 275 | - | HBDonor |
| SER 35 | cxb1.5 | GLU 275 | - | VdWContact |
| LEU 40 | cxb1.11 | PRO 29 | - | Hydrophobic |
| PRO 43 | cxb1.16 | MET 20 | - | Hydrophobic |
| PRO 43 | cxb1.16 | MET 20 | - | VdWContact |
| LYS 45 | B1.2 | THR 18 | - | HBDonor |
| LYS 45 | B1.2 | THR 18 | - | VdWContact |
| GLN 48 | B1.5 | GLY 19 | - | VdWContact |
| GLN 48 | B1.5 | MET 20 | - | HBAcceptor |
| GLN 48 | B1.5 | MET 20 | - | Hydrophobic |
| GLN 48 | B1.5 | MET 20 | - | VdWContact |
| ALA 49 | B1.6 | MET 20 | - | VdWContact |
| GLU 50 | B1.7 | SER 28 | - | VdWContact |
| GLU 50 | B1.7 | PRO 29 | - | Hydrophobic |
| LEU 51 | b1b2.4 | MET 20 | - | Hydrophobic |
| LEU 51 | b1b2.4 | MET 20 | - | VdWContact |
| LEU 51 | b1b2.4 | ALA 23 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 27 | - | Hydrophobic |
| CYS 52 | b1b2.6 | TYR 27 | - | HBDonor |
| CYS 52 | b1b2.6 | TYR 27 | - | VdWContact |
| CYS 52 | b1b2.6 | PRO 29 | - | VdWContact |
| GLN 62 | B2.2 | TRP 10 | - | Hydrophobic |
| GLN 62 | B2.2 | TRP 10 | - | VdWContact |
| LEU 63 | B2.3 | TRP 10 | - | Hydrophobic |
| LYS 75 | B3.3 | ASN 181 | - | VdWContact |
