Predicted complex interactions
CCL22_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 106
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | ASP 288 | 7.36x35 | Cationic |
| GLY 1 | NTc.Cm35 | ASP 288 | 7.36x35 | HBDonor |
| GLY 1 | NTc.Cm35 | ASP 288 | 7.36x35 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 46 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 95 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 95 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | LYS 117 | 3.32x32 | HBAcceptor |
| PRO 2 | NTc.Cm34 | LYS 117 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LYS 117 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm34 | ARG 175 | 4.64x65 | HBAcceptor |
| PRO 2 | NTc.Cm34 | ARG 175 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm34 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 295 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm34 | PHE 295 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | LYS 117 | 3.32x32 | PiCation |
| TYR 3 | NTc.Cm33 | LYS 117 | 3.32x32 | VdWContact |
| TYR 3 | NTc.Cm33 | ARG 175 | 4.64x65 | VdWContact |
| TYR 3 | NTc.Cm33 | TRP 255 | 6.48x48 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 258 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 258 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 291 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 291 | 7.39x38 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 291 | 7.39x38 | VdWContact |
| TYR 3 | NTc.Cm33 | PHE 295 | 7.43x42 | Hydrophobic |
| GLY 4 | NTc.Cm32 | ARG 175 | 4.64x65 | HBAcceptor |
| ALA 5 | NTc.Cm31 | VAL 186 | - | Hydrophobic |
| ALA 5 | NTc.Cm31 | TYR 188 | 45.51x51 | VdWContact |
| ASN 6 | NTc.Cm30 | ARG 199 | 5.35x36 | HBAcceptor |
| ASN 6 | NTc.Cm30 | ARG 199 | 5.35x36 | VdWContact |
| ASN 6 | NTc.Cm30 | ASP 265 | 6.58x58 | HBDonor |
| ASN 6 | NTc.Cm30 | ASP 265 | 6.58x58 | VdWContact |
| MET 7 | NTc.Cm29 | LEU 32 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | LEU 32 | - | VdWContact |
| MET 7 | NTc.Cm29 | TYR 178 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | PRO 180 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | PRO 180 | - | VdWContact |
| MET 7 | NTc.Cm29 | VAL 186 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | VAL 186 | - | VdWContact |
| MET 7 | NTc.Cm29 | TYR 188 | 45.51x51 | Hydrophobic |
| GLU 8 | NTc.Cm28 | TYR 188 | 45.51x51 | HBAcceptor |
| GLU 8 | NTc.Cm28 | TYR 188 | 45.51x51 | HBDonor |
| GLU 8 | NTc.Cm28 | TYR 188 | 45.51x51 | VdWContact |
| GLU 8 | NTc.Cm28 | THR 195 | 5.31x32 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ALA 196 | 5.32x33 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ALA 196 | 5.32x33 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 199 | 5.35x36 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 199 | 5.35x36 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 199 | 5.35x36 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 269 | 6.62x62 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 269 | 6.62x62 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 269 | 6.62x62 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 269 | 6.62x62 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 269 | 6.62x62 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 269 | 6.62x62 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 280 | 7.28x27 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 280 | 7.28x27 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 280 | 7.28x27 | VdWContact |
| SER 10 | NTc.Cm26 | LEU 32 | - | VdWContact |
| SER 10 | NTc.Cm26 | ARG 280 | 7.28x27 | HBAcceptor |
| VAL 11 | NTc.Cm25 | PRO 29 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | ASP 26 | - | Cationic |
| ARG 14 | NTc.Cm22 | ASP 26 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 30 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 30 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 275 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 275 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | GLU 275 | - | VdWContact |
| ARG 14 | NTc.Cm22 | SER 276 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 277 | 7.25x24 | Cationic |
| ASP 15 | NTc.Cm21 | TYR 27 | - | Hydrophobic |
| TYR 16 | NTc.Cm20 | TYR 27 | - | VdWContact |
| VAL 17 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| ARG 18 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PRO 21 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PRO 21 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ALA 23 | - | VdWContact |
| PRO 22 | NTc.Cm14 | PHE 17 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | ASP 14 | - | Cationic |
| ARG 24 | NTc.Cm12 | ASP 14 | - | HBDonor |
| ARG 24 | NTc.Cm12 | ASP 14 | - | VdWContact |
| ARG 24 | NTc.Cm12 | LEU 15 | - | HBDonor |
| ARG 24 | NTc.Cm12 | LEU 15 | - | VdWContact |
| VAL 25 | NTc.Cm11 | MET 20 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | ASN 193 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | ASN 193 | - | VdWContact |
| SER 35 | NTc.Cm1 | ASN 193 | - | VdWContact |
| SER 35 | NTc.Cm1 | THR 195 | 5.31x32 | VdWContact |
| SER 35 | NTc.Cm1 | ALA 196 | 5.32x33 | VdWContact |
| VAL 42 | cxb1.7 | PRO 29 | - | Hydrophobic |
| THR 45 | cxb1.11 | MET 20 | - | Hydrophobic |
| ARG 47 | cxb1.15 | THR 18 | - | HBDonor |
| ARG 47 | cxb1.15 | THR 18 | - | VdWContact |
| ARG 47 | cxb1.15 | MET 20 | - | Hydrophobic |
| ARG 47 | cxb1.15 | MET 20 | - | VdWContact |
| LYS 49 | B1.1 | MET 20 | - | Hydrophobic |
| LYS 49 | B1.1 | ALA 23 | - | HBDonor |
| LYS 49 | B1.1 | ALA 23 | - | Hydrophobic |
| GLU 50 | B1.2 | SER 28 | - | VdWContact |
| GLU 50 | B1.2 | PRO 29 | - | Hydrophobic |
| ILE 51 | B1.3 | ALA 23 | - | Hydrophobic |
| ILE 51 | B1.3 | TYR 27 | - | Hydrophobic |
| CYS 52 | B1.4 | TYR 27 | - | HBDonor |
| CYS 52 | B1.4 | TYR 27 | - | VdWContact |
