Predicted complex interactions
CCL27_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 102
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | GLU 118 | 3.33x33 | Cationic |
| PHE 1 | NTc.Cm32 | GLU 118 | 3.33x33 | HBDonor |
| PHE 1 | NTc.Cm32 | GLU 118 | 3.33x33 | VdWContact |
| PHE 1 | NTc.Cm32 | ARG 175 | 4.64x65 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 189 | 45.52x52 | Cationic |
| PHE 1 | NTc.Cm32 | PRO 206 | 5.42x43 | Hydrophobic |
| PHE 1 | NTc.Cm32 | PRO 206 | 5.42x43 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 258 | 6.51x51 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 258 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm32 | LEU 262 | 6.55x55 | Hydrophobic |
| PHE 1 | NTc.Cm32 | LEU 262 | 6.55x55 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 95 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 95 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | LYS 117 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm31 | ARG 175 | 4.64x65 | HBAcceptor |
| LEU 2 | NTc.Cm31 | ARG 175 | 4.64x65 | VdWContact |
| LEU 2 | NTc.Cm31 | GLU 291 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm30 | ARG 199 | 5.35x36 | VdWContact |
| LEU 3 | NTc.Cm30 | LEU 287 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm30 | LEU 287 | 7.35x34 | VdWContact |
| PRO 4 | NTc.Cm29 | VAL 186 | - | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 188 | 45.51x51 | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 188 | 45.51x51 | VdWContact |
| PRO 4 | NTc.Cm29 | ARG 199 | 5.35x36 | VdWContact |
| PRO 5 | NTc.Cm28 | LEU 32 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | VAL 186 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | VAL 186 | - | VdWContact |
| SER 6 | NTc.Cm27 | LEU 32 | - | VdWContact |
| THR 7 | NTc.Cm26 | LEU 32 | - | VdWContact |
| THR 7 | NTc.Cm26 | PRO 180 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | PRO 29 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 30 | - | VdWContact |
| ALA 8 | NTc.Cm25 | LEU 32 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | LEU 32 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 30 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 30 | - | VdWContact |
| CYS 9 | NTc.Cm24 | ARG 280 | 7.28x27 | Anionic |
| CYS 9 | NTc.Cm24 | ARG 280 | 7.28x27 | VdWContact |
| THR 11 | NTc.Cm22 | CYS 30 | - | VdWContact |
| THR 11 | NTc.Cm22 | GLU 275 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | GLU 275 | - | VdWContact |
| GLN 12 | NTc.Cm21 | ASP 26 | - | HBDonor |
| GLN 12 | NTc.Cm21 | ASP 26 | - | VdWContact |
| GLN 12 | NTc.Cm21 | TYR 27 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 17 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 17 | - | VdWContact |
| TYR 14 | NTc.Cm19 | PRO 21 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PRO 21 | - | VdWContact |
| TYR 14 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | TYR 27 | - | PiStacking |
| ARG 15 | NTc.Cm18 | GLN 8 | - | VdWContact |
| ARG 15 | NTc.Cm18 | TRP 10 | - | Hydrophobic |
| ARG 15 | NTc.Cm18 | TRP 10 | - | VdWContact |
| LYS 16 | NTc.Cm17 | PHE 17 | - | Hydrophobic |
| LYS 16 | NTc.Cm17 | PHE 17 | - | VdWContact |
| PRO 17 | NTc.Cm16 | PHE 12 | - | Hydrophobic |
| PRO 17 | NTc.Cm16 | PHE 12 | - | VdWContact |
| PRO 17 | NTc.Cm16 | GLY 19 | - | VdWContact |
| LEU 18 | NTc.Cm15 | GLY 19 | - | VdWContact |
| LEU 18 | NTc.Cm15 | PRO 21 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | PRO 21 | - | VdWContact |
| SER 19 | NTc.Cm14 | GLY 19 | - | HBDonor |
| SER 19 | NTc.Cm14 | GLY 19 | - | VdWContact |
| LEU 22 | NTc.Cm11 | MET 20 | - | Hydrophobic |
| GLU 30 | NTc.Cm3 | ASN 181 | - | HBAcceptor |
| GLU 30 | NTc.Cm3 | ASN 181 | - | VdWContact |
| ASP 35 | cxb1.1 | GLY 192 | - | VdWContact |
| ASP 35 | cxb1.1 | THR 195 | 5.31x32 | HBAcceptor |
| ASP 35 | cxb1.1 | THR 195 | 5.31x32 | VdWContact |
| ASP 35 | cxb1.1 | ALA 196 | 5.32x33 | HBAcceptor |
| ASP 35 | cxb1.1 | ALA 196 | 5.32x33 | VdWContact |
| GLY 36 | cxb1.2 | TYR 188 | 45.51x51 | VdWContact |
| GLY 36 | cxb1.2 | ALA 196 | 5.32x33 | VdWContact |
| GLY 36 | cxb1.2 | ARG 269 | 6.62x62 | VdWContact |
| ASP 37 | cxb1.5 | ARG 199 | 5.35x36 | Anionic |
| ASP 37 | cxb1.5 | ARG 199 | 5.35x36 | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 199 | 5.35x36 | VdWContact |
| ASP 37 | cxb1.5 | ARG 269 | 6.62x62 | Anionic |
| ASP 37 | cxb1.5 | ARG 269 | 6.62x62 | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 269 | 6.62x62 | VdWContact |
| ASP 37 | cxb1.5 | ARG 280 | 7.28x27 | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 280 | 7.28x27 | VdWContact |
| HIS 39 | cxb1.7 | ARG 269 | 6.62x62 | Hydrophobic |
| HIS 39 | cxb1.7 | ARG 269 | 6.62x62 | VdWContact |
| HIS 39 | cxb1.7 | GLU 275 | - | HBDonor |
| HIS 39 | cxb1.7 | GLU 275 | - | VdWContact |
| VAL 44 | cxb1.15 | PRO 29 | - | Hydrophobic |
| ARG 50 | B1.2 | PRO 21 | - | HBDonor |
| ARG 50 | B1.2 | PRO 21 | - | VdWContact |
| ARG 50 | B1.2 | PRO 22 | - | HBDonor |
| ARG 50 | B1.2 | PRO 22 | - | VdWContact |
| ARG 50 | B1.2 | ALA 23 | - | VdWContact |
| ILE 52 | B1.4 | PRO 21 | - | Hydrophobic |
| ILE 52 | B1.4 | PRO 21 | - | VdWContact |
| ILE 52 | B1.4 | TYR 27 | - | VdWContact |
| CYS 53 | B1.5 | TYR 27 | - | HBDonor |
| CYS 53 | B1.5 | TYR 27 | - | VdWContact |
| CYS 53 | B1.5 | SER 28 | - | VdWContact |
| CYS 53 | B1.5 | PRO 29 | - | VdWContact |
| GLN 57 | b1b2.6 | TRP 10 | - | VdWContact |
| PRO 59 | b1b2.8 | TRP 10 | - | Hydrophobic |
| PRO 59 | b1b2.8 | PHE 12 | - | Hydrophobic |
