Predicted complex interactions
CCL8_HUMAN + CXCR1
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 4 | NTc.Cm30 | VAL 100 | 2.65x65 | HBDonor |
| SER 4 | NTc.Cm30 | VAL 100 | 2.65x65 | VdWContact |
| SER 4 | NTc.Cm30 | ASN 101 | 2.66x66 | VdWContact |
| SER 6 | NTc.Cm28 | THR 34 | - | VdWContact |
| SER 6 | NTc.Cm28 | GLU 35 | - | VdWContact |
| ILE 7 | NTc.Cm27 | THR 34 | - | HBAcceptor |
| ILE 7 | NTc.Cm27 | THR 34 | - | VdWContact |
| ILE 7 | NTc.Cm27 | ASN 182 | - | VdWContact |
| ILE 7 | NTc.Cm27 | SER 183 | - | VdWContact |
| PRO 8 | NTc.Cm26 | MET 31 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | MET 31 | - | VdWContact |
| PRO 8 | NTc.Cm26 | LEU 32 | - | VdWContact |
| ILE 9 | NTc.Cm25 | LEU 32 | - | HBAcceptor |
| ILE 9 | NTc.Cm25 | LEU 32 | - | HBDonor |
| ILE 9 | NTc.Cm25 | LEU 32 | - | Hydrophobic |
| ILE 9 | NTc.Cm25 | LEU 32 | - | VdWContact |
| ILE 9 | NTc.Cm25 | THR 34 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 29 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 29 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 30 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 30 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 30 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 30 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LEU 32 | - | Hydrophobic |
| CYS 11 | NTc.Cm23 | LEU 32 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 30 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 30 | - | VdWContact |
| PHE 13 | NTc.Cm21 | LEU 32 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 275 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 275 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ARG 280 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | ARG 280 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ASP 26 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASP 26 | - | VdWContact |
| ASN 14 | NTc.Cm20 | TYR 27 | - | Hydrophobic |
| VAL 15 | NTc.Cm19 | TYR 27 | - | VdWContact |
| ILE 16 | NTc.Cm18 | PRO 21 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PRO 21 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | PRO 21 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 24 | - | Cationic |
| ILE 20 | NTc.Cm14 | MET 20 | - | Hydrophobic |
| ILE 20 | NTc.Cm14 | MET 20 | - | VdWContact |
| ARG 24 | NTc.Cm10 | THR 18 | - | HBDonor |
| ARG 24 | NTc.Cm10 | THR 18 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLY 19 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLY 19 | - | VdWContact |
| ARG 24 | NTc.Cm10 | MET 20 | - | HBDonor |
| ARG 24 | NTc.Cm10 | MET 20 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | MET 20 | - | VdWContact |
| ILE 34 | CX.1 | TYR 178 | - | HBDonor |
| ILE 34 | CX.1 | TYR 178 | - | Hydrophobic |
| ILE 34 | CX.1 | TYR 178 | - | VdWContact |
| ILE 34 | CX.1 | TYR 188 | 45.51x51 | Hydrophobic |
| ILE 34 | CX.1 | TYR 188 | 45.51x51 | VdWContact |
| ILE 34 | CX.1 | VAL 190 | - | Hydrophobic |
| ILE 34 | CX.1 | VAL 190 | - | VdWContact |
| GLN 35 | CX.5 | TYR 188 | 45.51x51 | Hydrophobic |
| GLN 35 | CX.5 | TYR 188 | 45.51x51 | VdWContact |
| ILE 42 | cxb1.10 | PRO 29 | - | Hydrophobic |
| ILE 42 | cxb1.10 | PRO 29 | - | VdWContact |
| THR 45 | cxb1.15 | MET 20 | - | Hydrophobic |
| THR 45 | cxb1.15 | MET 20 | - | VdWContact |
| ARG 47 | B1.1 | THR 18 | - | HBDonor |
| ARG 47 | B1.1 | THR 18 | - | VdWContact |
| GLU 50 | B1.4 | PRO 29 | - | Hydrophobic |
| VAL 51 | B1.5 | ALA 23 | - | Hydrophobic |
| VAL 51 | B1.5 | TYR 27 | - | Hydrophobic |
| CYS 52 | B1.6 | TYR 27 | - | HBDonor |
| CYS 52 | B1.6 | TYR 27 | - | VdWContact |
| CYS 52 | B1.6 | PRO 29 | - | VdWContact |
