Predicted complex interactions
CXCL10_HUMAN + CXCR1
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 114
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | LYS 117 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm29 | LYS 117 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | GLU 118 | 3.33x33 | Cationic |
| VAL 1 | NTc.Cm29 | GLU 118 | 3.33x33 | Hydrophobic |
| VAL 1 | NTc.Cm29 | GLU 118 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 258 | 6.51x51 | HBDonor |
| PRO 2 | NTc.Cm28 | LYS 117 | 3.32x32 | HBAcceptor |
| PRO 2 | NTc.Cm28 | LYS 117 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm28 | ARG 175 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 291 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 295 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm28 | PHE 295 | 7.43x42 | VdWContact |
| LEU 3 | NTc.Cm27 | ARG 199 | 5.35x36 | VdWContact |
| LEU 3 | NTc.Cm27 | ARG 203 | 5.39x40 | VdWContact |
| LEU 3 | NTc.Cm27 | LEU 262 | 6.55x55 | Hydrophobic |
| SER 4 | NTc.Cm26 | CYS 187 | 45.50x50 | VdWContact |
| SER 4 | NTc.Cm26 | TYR 188 | 45.51x51 | VdWContact |
| ARG 5 | NTc.Cm25 | THR 34 | - | HBDonor |
| ARG 5 | NTc.Cm25 | THR 34 | - | VdWContact |
| THR 6 | NTc.Cm24 | TYR 188 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm24 | ARG 269 | 6.62x62 | VdWContact |
| VAL 7 | NTc.Cm23 | TYR 178 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | TYR 178 | - | VdWContact |
| VAL 7 | NTc.Cm23 | PRO 180 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | VAL 186 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | TYR 188 | 45.51x51 | Hydrophobic |
| ARG 8 | NTc.Cm22 | ASP 265 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 265 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 265 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | MET 268 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | ARG 269 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm22 | GLU 275 | - | Cationic |
| CYS 9 | NTc.Cm21 | ARG 280 | 7.28x27 | HBAcceptor |
| CYS 9 | NTc.Cm21 | ARG 280 | 7.28x27 | VdWContact |
| THR 10 | NTc.Cm20 | CYS 30 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 30 | - | VdWContact |
| THR 10 | NTc.Cm20 | LEU 32 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 30 | - | VdWContact |
| ILE 12 | NTc.Cm18 | GLU 275 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | SER 276 | 7.24x23 | VdWContact |
| ILE 12 | NTc.Cm18 | ARG 280 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm17 | ASP 26 | - | HBDonor |
| SER 13 | NTc.Cm17 | ASP 26 | - | VdWContact |
| ILE 14 | NTc.Cm16 | TYR 27 | - | VdWContact |
| SER 15 | NTc.Cm15 | PRO 21 | - | VdWContact |
| SER 15 | NTc.Cm15 | PRO 22 | - | VdWContact |
| GLN 17 | NTc.Cm13 | PRO 21 | - | Hydrophobic |
| GLN 17 | NTc.Cm13 | PRO 21 | - | VdWContact |
| PRO 18 | NTc.Cm12 | PHE 17 | - | Hydrophobic |
| PRO 18 | NTc.Cm12 | GLY 19 | - | VdWContact |
| PRO 18 | NTc.Cm12 | PRO 21 | - | VdWContact |
| VAL 19 | NTc.Cm11 | GLY 19 | - | VdWContact |
| VAL 19 | NTc.Cm11 | PRO 21 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | PRO 21 | - | VdWContact |
| ASN 20 | NTc.Cm10 | PHE 17 | - | VdWContact |
| ASN 20 | NTc.Cm10 | GLY 19 | - | HBDonor |
| ASN 20 | NTc.Cm10 | GLY 19 | - | VdWContact |
| PRO 21 | NTc.Cm9 | PHE 12 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 12 | - | VdWContact |
| PRO 21 | NTc.Cm9 | LEU 15 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 17 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 17 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 13 | - | Cationic |
| LEU 24 | NTc.Cm6 | PRO 7 | - | Hydrophobic |
| LEU 24 | NTc.Cm6 | PRO 7 | - | VdWContact |
| GLU 25 | NTc.Cm5 | PRO 7 | - | VdWContact |
| LYS 26 | NTc.Cm4 | ILE 4 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | ILE 4 | - | VdWContact |
| LEU 27 | NTc.Cm3 | ILE 4 | - | VdWContact |
| LEU 27 | NTc.Cm3 | THR 5 | - | HBAcceptor |
| LEU 27 | NTc.Cm3 | THR 5 | - | HBDonor |
| LEU 27 | NTc.Cm3 | THR 5 | - | VdWContact |
| LEU 27 | NTc.Cm3 | TRP 10 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | SER 2 | - | VdWContact |
| GLN 34 | cxb1.2 | VAL 190 | - | VdWContact |
| GLN 34 | cxb1.2 | THR 195 | 5.31x32 | VdWContact |
| PHE 35 | cxb1.5 | TYR 178 | - | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 178 | - | VdWContact |
| PHE 35 | cxb1.5 | TYR 188 | 45.51x51 | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 188 | 45.51x51 | VdWContact |
| PHE 35 | cxb1.5 | VAL 190 | - | Hydrophobic |
| PHE 35 | cxb1.5 | VAL 190 | - | VdWContact |
| PHE 35 | cxb1.5 | THR 195 | 5.31x32 | Hydrophobic |
| PHE 35 | cxb1.5 | THR 195 | 5.31x32 | VdWContact |
| ILE 42 | cxb1.15 | PRO 29 | - | Hydrophobic |
| MET 45 | B1.2 | MET 20 | - | Hydrophobic |
| LYS 51 | b1b2.4 | SER 28 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 29 | - | Hydrophobic |
| LYS 51 | b1b2.4 | PRO 29 | - | VdWContact |
| ARG 52 | b1b2.6 | MET 20 | - | VdWContact |
| ARG 52 | b1b2.6 | PRO 21 | - | Hydrophobic |
| ARG 52 | b1b2.6 | PRO 21 | - | VdWContact |
| ARG 52 | b1b2.6 | ALA 23 | - | VdWContact |
| ARG 52 | b1b2.6 | TYR 27 | - | VdWContact |
| CYS 53 | b1b2.7 | TYR 27 | - | HBDonor |
| CYS 53 | b1b2.7 | TYR 27 | - | VdWContact |
| LEU 54 | b1b2.8 | PRO 21 | - | Hydrophobic |
| ALA 60 | b1b2.16 | PHE 17 | - | Hydrophobic |
| ASN 63 | B2.3 | PHE 17 | - | Hydrophobic |
| ASN 63 | B2.3 | PHE 17 | - | VdWContact |
| LEU 64 | B2.4 | TRP 10 | - | Hydrophobic |
| LEU 64 | B2.4 | PHE 12 | - | Hydrophobic |
| LEU 64 | B2.4 | PHE 17 | - | Hydrophobic |
| ALA 67 | b2b3.2 | LEU 15 | - | Hydrophobic |
| ALA 67 | b2b3.2 | LEU 15 | - | VdWContact |
| VAL 68 | b2b3.3 | THR 5 | - | Hydrophobic |
| VAL 68 | b2b3.3 | THR 5 | - | VdWContact |
| VAL 68 | b2b3.3 | TRP 10 | - | Hydrophobic |
| VAL 68 | b2b3.3 | TRP 10 | - | VdWContact |
| GLU 71 | b2b3.12 | TRP 10 | - | Hydrophobic |
| GLU 71 | b2b3.12 | TRP 10 | - | VdWContact |
| ARG 72 | B3.1 | ASN 3 | - | VdWContact |
| ARG 75 | B3.4 | MET 9 | - | VdWContact |
