Predicted complex interactions
CXCL2_HUMAN + CXCR1
SUMMARY
- Chemokine
- CXCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | LYS 117 | 3.32x32 | HBAcceptor |
| ALA 1 | NTc.Cm42 | LYS 117 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm42 | GLU 118 | 3.33x33 | Cationic |
| ALA 1 | NTc.Cm42 | GLU 118 | 3.33x33 | HBDonor |
| ALA 1 | NTc.Cm42 | GLU 118 | 3.33x33 | VdWContact |
| ALA 1 | NTc.Cm42 | PHE 121 | 3.36x36 | CationPi |
| ALA 1 | NTc.Cm42 | TRP 255 | 6.48x48 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TYR 258 | 6.51x51 | HBAcceptor |
| PRO 2 | NTc.Cm41 | TYR 258 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TYR 258 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm41 | LEU 262 | 6.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm41 | GLU 291 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm40 | TYR 46 | 1.39x39 | VdWContact |
| LEU 3 | NTc.Cm40 | TRP 95 | 2.60x60 | Hydrophobic |
| LEU 3 | NTc.Cm40 | TRP 95 | 2.60x60 | VdWContact |
| LEU 3 | NTc.Cm40 | LYS 117 | 3.32x32 | HBAcceptor |
| LEU 3 | NTc.Cm40 | LYS 117 | 3.32x32 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LYS 117 | 3.32x32 | VdWContact |
| LEU 3 | NTc.Cm40 | GLU 291 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm40 | PHE 295 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm40 | PHE 295 | 7.43x42 | VdWContact |
| THR 5 | NTc.Cm38 | GLU 33 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | VAL 186 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | TYR 188 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 199 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 199 | 5.35x36 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 199 | 5.35x36 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 203 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 203 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 203 | 5.39x40 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 269 | 6.62x62 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 269 | 6.62x62 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 269 | 6.62x62 | VdWContact |
| GLU 6 | NTc.Cm37 | LEU 287 | 7.35x34 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LEU 32 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | GLU 33 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | TYR 178 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | PRO 180 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | VAL 186 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | TYR 188 | 45.51x51 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 269 | 6.62x62 | HBAcceptor |
| LEU 7 | NTc.Cm36 | ARG 269 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 265 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 265 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 265 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | MET 268 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | GLU 275 | - | Cationic |
| CYS 9 | NTc.Cm34 | ARG 280 | 7.28x27 | HBAcceptor |
| CYS 9 | NTc.Cm34 | ARG 280 | 7.28x27 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 29 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | CYS 30 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 30 | - | HBDonor |
| GLN 10 | NTc.Cm33 | CYS 30 | - | VdWContact |
| GLN 10 | NTc.Cm33 | LEU 32 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | LEU 32 | - | VdWContact |
| LEU 12 | NTc.Cm31 | GLU 275 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | SER 276 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm31 | ARG 280 | 7.28x27 | VdWContact |
| GLN 13 | NTc.Cm30 | TYR 27 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | PRO 21 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 27 | - | Hydrophobic |
| GLN 16 | NTc.Cm27 | PHE 17 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | PRO 21 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | PRO 21 | - | VdWContact |
| HIS 19 | NTc.Cm24 | PHE 17 | - | VdWContact |
| LEU 20 | NTc.Cm23 | PHE 12 | - | Hydrophobic |
| ASN 22 | NTc.Cm21 | GLY 19 | - | HBDonor |
| ASN 22 | NTc.Cm21 | GLY 19 | - | VdWContact |
| LYS 27 | NTc.Cm16 | ASN 182 | - | VdWContact |
| LYS 29 | NTc.Cm14 | LEU 32 | - | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 178 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | TYR 178 | - | VdWContact |
| PRO 33 | NTc.Cm10 | VAL 190 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | VAL 190 | - | VdWContact |
| PRO 33 | NTc.Cm10 | THR 195 | 5.31x32 | Hydrophobic |
| PRO 33 | NTc.Cm10 | THR 195 | 5.31x32 | VdWContact |
| HIS 34 | NTc.Cm9 | LEU 32 | - | Hydrophobic |
| HIS 34 | NTc.Cm9 | TYR 178 | - | HBDonor |
| HIS 34 | NTc.Cm9 | TYR 178 | - | Hydrophobic |
| HIS 34 | NTc.Cm9 | TYR 178 | - | VdWContact |
| HIS 34 | NTc.Cm9 | PRO 180 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | PRO 29 | - | Hydrophobic |
| LEU 44 | CX.4 | PRO 21 | - | Hydrophobic |
| ASN 46 | cxb1.1 | MET 20 | - | VdWContact |
| LYS 49 | cxb1.6 | SER 28 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 29 | - | Hydrophobic |
| ALA 50 | cxb1.8 | TYR 27 | - | VdWContact |
| CYS 51 | cxb1.10 | TYR 27 | - | HBDonor |
| CYS 51 | cxb1.10 | TYR 27 | - | VdWContact |
| CYS 51 | cxb1.10 | PRO 29 | - | VdWContact |
| MET 58 | B1.3 | LEU 15 | - | Hydrophobic |
| MET 58 | B1.3 | PHE 17 | - | Hydrophobic |
| MET 58 | B1.3 | PHE 17 | - | VdWContact |
| LYS 61 | B1.6 | TRP 10 | - | CationPi |
| LYS 61 | B1.6 | PHE 12 | - | Hydrophobic |
| ILE 62 | B1.7 | PHE 12 | - | Hydrophobic |
| LYS 65 | b1b2.7 | PHE 12 | - | Hydrophobic |
