Predicted complex interactions
CXCL4_HUMAN + CXCR1
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 115
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 2 | NTc.Cm39 | LYS 39 | 1.32x32 | HBAcceptor |
| ALA 2 | NTc.Cm39 | LYS 39 | 1.32x32 | VdWContact |
| GLU 3 | NTc.Cm38 | LEU 32 | - | Hydrophobic |
| GLU 3 | NTc.Cm38 | LEU 32 | - | VdWContact |
| GLU 3 | NTc.Cm38 | SER 183 | - | HBAcceptor |
| GLU 3 | NTc.Cm38 | SER 183 | - | VdWContact |
| GLU 3 | NTc.Cm38 | SER 184 | - | VdWContact |
| GLU 4 | NTc.Cm37 | THR 36 | 1.29x29 | HBAcceptor |
| GLU 4 | NTc.Cm37 | THR 36 | 1.29x29 | Hydrophobic |
| GLU 4 | NTc.Cm37 | THR 36 | 1.29x29 | VdWContact |
| GLU 4 | NTc.Cm37 | LYS 39 | 1.32x32 | Anionic |
| GLU 4 | NTc.Cm37 | LYS 39 | 1.32x32 | VdWContact |
| ASP 5 | NTc.Cm36 | SER 98 | 2.63x63 | HBAcceptor |
| ASP 5 | NTc.Cm36 | SER 98 | 2.63x63 | VdWContact |
| ASP 5 | NTc.Cm36 | LYS 99 | 2.64x64 | Hydrophobic |
| ASP 5 | NTc.Cm36 | LYS 99 | 2.64x64 | VdWContact |
| ASP 7 | NTc.Cm34 | TYR 188 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 199 | 5.35x36 | Anionic |
| ASP 7 | NTc.Cm34 | ARG 199 | 5.35x36 | HBAcceptor |
| ASP 7 | NTc.Cm34 | ARG 199 | 5.35x36 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 203 | 5.39x40 | Anionic |
| ASP 7 | NTc.Cm34 | ARG 203 | 5.39x40 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 269 | 6.62x62 | Anionic |
| ASP 7 | NTc.Cm34 | ARG 269 | 6.62x62 | VdWContact |
| LEU 8 | NTc.Cm33 | TYR 178 | - | Hydrophobic |
| LEU 8 | NTc.Cm33 | TYR 178 | - | VdWContact |
| LEU 8 | NTc.Cm33 | PRO 180 | - | Hydrophobic |
| LEU 8 | NTc.Cm33 | VAL 186 | - | Hydrophobic |
| LEU 8 | NTc.Cm33 | TYR 188 | 45.51x51 | Hydrophobic |
| LEU 8 | NTc.Cm33 | TYR 188 | 45.51x51 | VdWContact |
| LEU 8 | NTc.Cm33 | ARG 269 | 6.62x62 | HBAcceptor |
| LEU 8 | NTc.Cm33 | ARG 269 | 6.62x62 | VdWContact |
| GLN 9 | NTc.Cm32 | ARG 269 | 6.62x62 | VdWContact |
| GLN 9 | NTc.Cm32 | ARG 280 | 7.28x27 | VdWContact |
| CYS 10 | NTc.Cm31 | ARG 280 | 7.28x27 | HBAcceptor |
| CYS 10 | NTc.Cm31 | ARG 280 | 7.28x27 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 29 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | PRO 29 | - | VdWContact |
| LEU 11 | NTc.Cm30 | CYS 30 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 30 | - | VdWContact |
| LEU 11 | NTc.Cm30 | LEU 32 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | LEU 32 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 30 | - | VdWContact |
| VAL 13 | NTc.Cm28 | GLU 275 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | GLU 275 | - | VdWContact |
| VAL 13 | NTc.Cm28 | ARG 280 | 7.28x27 | VdWContact |
| LYS 14 | NTc.Cm27 | ASP 24 | - | Cationic |
| LYS 14 | NTc.Cm27 | ASP 26 | - | Cationic |
| LYS 14 | NTc.Cm27 | ASP 26 | - | HBDonor |
| LYS 14 | NTc.Cm27 | ASP 26 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | ASP 26 | - | VdWContact |
| LYS 14 | NTc.Cm27 | TYR 27 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | PRO 22 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | PRO 22 | - | VdWContact |
| THR 16 | NTc.Cm25 | TYR 27 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | TYR 27 | - | VdWContact |
| SER 17 | NTc.Cm24 | PHE 17 | - | VdWContact |
| VAL 19 | NTc.Cm22 | PRO 21 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | PHE 17 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | PHE 17 | - | VdWContact |
| ARG 20 | NTc.Cm21 | THR 18 | - | VdWContact |
| PRO 21 | NTc.Cm20 | TRP 10 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | TRP 10 | - | VdWContact |
| ILE 24 | NTc.Cm17 | TRP 10 | - | Hydrophobic |
| ILE 24 | NTc.Cm17 | TRP 10 | - | VdWContact |
| SER 26 | NTc.Cm15 | ILE 4 | - | VdWContact |
| LEU 27 | NTc.Cm14 | ASN 3 | - | VdWContact |
| LEU 27 | NTc.Cm14 | ILE 4 | - | HBAcceptor |
| LEU 27 | NTc.Cm14 | ILE 4 | - | HBDonor |
| LEU 27 | NTc.Cm14 | ILE 4 | - | Hydrophobic |
| LEU 27 | NTc.Cm14 | ILE 4 | - | VdWContact |
| LEU 27 | NTc.Cm14 | TRP 10 | - | Hydrophobic |
| LEU 27 | NTc.Cm14 | TRP 10 | - | VdWContact |
| GLU 28 | NTc.Cm13 | MET 1 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | MET 1 | - | VdWContact |
| GLU 28 | NTc.Cm13 | SER 2 | - | VdWContact |
| VAL 29 | NTc.Cm12 | MET 1 | - | VdWContact |
| VAL 29 | NTc.Cm12 | ILE 4 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | MET 1 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | TYR 178 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | TYR 178 | - | VdWContact |
| PRO 34 | NTc.Cm7 | VAL 190 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | VAL 190 | - | VdWContact |
| PRO 34 | NTc.Cm7 | THR 195 | 5.31x32 | Hydrophobic |
| PRO 34 | NTc.Cm7 | THR 195 | 5.31x32 | VdWContact |
| HIS 35 | NTc.Cm6 | TYR 178 | - | HBDonor |
| HIS 35 | NTc.Cm6 | TYR 178 | - | VdWContact |
| ILE 42 | CX.4 | PRO 29 | - | Hydrophobic |
| LEU 45 | cxb1.2 | PRO 21 | - | Hydrophobic |
| ARG 49 | cxb1.10 | PRO 22 | - | VdWContact |
| ARG 49 | cxb1.10 | ALA 23 | - | HBDonor |
| ARG 49 | cxb1.10 | ALA 23 | - | VdWContact |
| ARG 49 | cxb1.10 | ASP 24 | - | VdWContact |
| ARG 49 | cxb1.10 | SER 28 | - | HBDonor |
| ARG 49 | cxb1.10 | SER 28 | - | VdWContact |
| LYS 50 | cxb1.11 | SER 28 | - | HBAcceptor |
| LYS 50 | cxb1.11 | SER 28 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 29 | - | Hydrophobic |
| ILE 51 | cxb1.14 | PRO 21 | - | Hydrophobic |
| ILE 51 | cxb1.14 | PRO 22 | - | Hydrophobic |
| ILE 51 | cxb1.14 | TYR 27 | - | Hydrophobic |
| ILE 51 | cxb1.14 | TYR 27 | - | VdWContact |
| CYS 52 | cxb1.15 | TYR 27 | - | HBDonor |
| CYS 52 | cxb1.15 | TYR 27 | - | VdWContact |
| LEU 59 | B1.6 | PHE 12 | - | Hydrophobic |
| LEU 59 | B1.6 | LEU 15 | - | Hydrophobic |
| LEU 59 | B1.6 | LEU 15 | - | VdWContact |
| LEU 59 | B1.6 | PHE 17 | - | Hydrophobic |
| ILE 63 | b1b2.7 | TRP 10 | - | Hydrophobic |
| ILE 63 | b1b2.7 | PHE 12 | - | Hydrophobic |
| LYS 66 | b1b2.10 | MET 9 | - | Hydrophobic |
| LYS 66 | b1b2.10 | MET 9 | - | VdWContact |
| LEU 67 | b1b2.12 | ILE 4 | - | Hydrophobic |
| LEU 67 | b1b2.12 | ILE 4 | - | VdWContact |
| LEU 67 | b1b2.12 | MET 9 | - | Hydrophobic |
