Predicted complex interactions
CXCL5_HUMAN + CXCR1
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 117
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 5 | NTc.Cm44 | SER 184 | - | HBAcceptor |
| ALA 5 | NTc.Cm44 | SER 184 | - | VdWContact |
| ALA 6 | NTc.Cm43 | LEU 32 | - | VdWContact |
| ALA 6 | NTc.Cm43 | THR 34 | - | Hydrophobic |
| ALA 6 | NTc.Cm43 | THR 34 | - | VdWContact |
| ALA 6 | NTc.Cm43 | SER 183 | - | VdWContact |
| ALA 6 | NTc.Cm43 | SER 184 | - | HBAcceptor |
| ALA 6 | NTc.Cm43 | SER 184 | - | VdWContact |
| VAL 7 | NTc.Cm42 | THR 34 | - | Hydrophobic |
| VAL 7 | NTc.Cm42 | THR 34 | - | VdWContact |
| LEU 8 | NTc.Cm41 | LEU 32 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 32 | - | VdWContact |
| LEU 8 | NTc.Cm41 | PRO 180 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | VAL 186 | - | Hydrophobic |
| ARG 9 | NTc.Cm40 | TYR 188 | 45.51x51 | VdWContact |
| ARG 9 | NTc.Cm40 | TYR 258 | 6.51x51 | VdWContact |
| ARG 9 | NTc.Cm40 | LEU 287 | 7.35x34 | VdWContact |
| ARG 9 | NTc.Cm40 | ASP 288 | 7.36x35 | Cationic |
| ARG 9 | NTc.Cm40 | ASP 288 | 7.36x35 | HBDonor |
| ARG 9 | NTc.Cm40 | ASP 288 | 7.36x35 | VdWContact |
| ARG 9 | NTc.Cm40 | GLU 291 | 7.39x38 | Cationic |
| ARG 9 | NTc.Cm40 | GLU 291 | 7.39x38 | HBDonor |
| ARG 9 | NTc.Cm40 | GLU 291 | 7.39x38 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 199 | 5.35x36 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 199 | 5.35x36 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 199 | 5.35x36 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 203 | 5.39x40 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 269 | 6.62x62 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 269 | 6.62x62 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 269 | 6.62x62 | VdWContact |
| GLU 10 | NTc.Cm39 | LEU 287 | 7.35x34 | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 178 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | PRO 180 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | VAL 186 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 188 | 45.51x51 | HBDonor |
| LEU 11 | NTc.Cm38 | TYR 188 | 45.51x51 | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 188 | 45.51x51 | VdWContact |
| LEU 11 | NTc.Cm38 | ARG 269 | 6.62x62 | HBAcceptor |
| LEU 11 | NTc.Cm38 | ARG 269 | 6.62x62 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 265 | 6.58x58 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 265 | 6.58x58 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 265 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | MET 268 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | GLU 275 | - | Cationic |
| CYS 13 | NTc.Cm36 | ARG 280 | 7.28x27 | HBAcceptor |
| CYS 13 | NTc.Cm36 | ARG 280 | 7.28x27 | VdWContact |
| VAL 14 | NTc.Cm35 | PRO 29 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | CYS 30 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 30 | - | VdWContact |
| VAL 14 | NTc.Cm35 | LEU 32 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 30 | - | VdWContact |
| LEU 16 | NTc.Cm33 | GLU 275 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | GLU 275 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 277 | 7.25x24 | VdWContact |
| LEU 16 | NTc.Cm33 | ARG 280 | 7.28x27 | VdWContact |
| GLN 17 | NTc.Cm32 | TYR 27 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | PRO 21 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | PRO 21 | - | VdWContact |
| GLY 21 | NTc.Cm28 | PRO 21 | - | VdWContact |
| VAL 22 | NTc.Cm27 | PRO 21 | - | Hydrophobic |
| VAL 22 | NTc.Cm27 | PRO 21 | - | VdWContact |
| HIS 23 | NTc.Cm26 | PHE 17 | - | VdWContact |
| PRO 24 | NTc.Cm25 | PHE 12 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | PHE 12 | - | VdWContact |
| PRO 24 | NTc.Cm25 | PHE 17 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | MET 20 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | MET 20 | - | VdWContact |
| ILE 27 | NTc.Cm22 | TRP 10 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | ASN 3 | - | VdWContact |
| LEU 30 | NTc.Cm19 | ILE 4 | - | HBAcceptor |
| LEU 30 | NTc.Cm19 | ILE 4 | - | HBDonor |
| LEU 30 | NTc.Cm19 | ILE 4 | - | VdWContact |
| LEU 30 | NTc.Cm19 | TRP 10 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | TRP 10 | - | VdWContact |
| GLN 31 | NTc.Cm18 | MET 1 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | MET 1 | - | VdWContact |
| GLN 31 | NTc.Cm18 | ASN 3 | - | VdWContact |
| GLN 31 | NTc.Cm18 | ASN 182 | - | HBAcceptor |
| GLN 31 | NTc.Cm18 | ASN 182 | - | VdWContact |
| VAL 32 | NTc.Cm17 | MET 1 | - | VdWContact |
| VAL 32 | NTc.Cm17 | SER 2 | - | HBDonor |
| VAL 32 | NTc.Cm17 | SER 2 | - | VdWContact |
| PHE 33 | NTc.Cm16 | MET 1 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | MET 1 | - | VdWContact |
| PHE 33 | NTc.Cm16 | ASN 181 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | ASN 181 | - | VdWContact |
| ILE 35 | NTc.Cm14 | ASN 193 | - | Hydrophobic |
| GLY 36 | NTc.Cm13 | ASN 193 | - | VdWContact |
| PRO 37 | NTc.Cm12 | TYR 178 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | VAL 190 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | VAL 190 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLY 192 | - | VdWContact |
| PRO 37 | NTc.Cm12 | THR 195 | 5.31x32 | Hydrophobic |
| PRO 37 | NTc.Cm12 | THR 195 | 5.31x32 | VdWContact |
| GLN 38 | NTc.Cm11 | TYR 178 | - | Hydrophobic |
| GLN 38 | NTc.Cm11 | ASN 181 | - | HBAcceptor |
| GLN 38 | NTc.Cm11 | ASN 181 | - | VdWContact |
| VAL 45 | NTc.Cm4 | PRO 29 | - | Hydrophobic |
| GLU 53 | cxb1.2 | SER 28 | - | HBAcceptor |
| GLU 53 | cxb1.2 | SER 28 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 29 | - | Hydrophobic |
| CYS 55 | cxb1.6 | TYR 27 | - | HBDonor |
| CYS 55 | cxb1.6 | TYR 27 | - | VdWContact |
| PHE 62 | B1.1 | TRP 10 | - | Hydrophobic |
| PHE 62 | B1.1 | PHE 12 | - | Hydrophobic |
| PHE 62 | B1.1 | LEU 15 | - | Hydrophobic |
| PHE 62 | B1.1 | LEU 15 | - | VdWContact |
| PHE 62 | B1.1 | PHE 17 | - | Hydrophobic |
| PHE 62 | B1.1 | PHE 17 | - | VdWContact |
| VAL 66 | B1.5 | ILE 4 | - | Hydrophobic |
| VAL 66 | B1.5 | TRP 10 | - | Hydrophobic |
| VAL 66 | B1.5 | TRP 10 | - | VdWContact |
| LYS 69 | b1b2.4 | MET 9 | - | HBDonor |
| LYS 69 | b1b2.4 | MET 9 | - | VdWContact |
| ILE 70 | b1b2.6 | SER 2 | - | VdWContact |
| ILE 70 | b1b2.6 | ILE 4 | - | Hydrophobic |
| ILE 70 | b1b2.6 | ILE 4 | - | VdWContact |
