Predicted complex interactions
CXCL6_HUMAN + CXCR1
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR1 View partner entry
- Partner description
- UniProt: P25024; Gene: cxcr1_human; Family: Chemokine
- Interactions detected
- 124
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 3 | NTc.Cm46 | THR 34 | - | Hydrophobic |
| VAL 3 | NTc.Cm46 | THR 34 | - | VdWContact |
| SER 4 | NTc.Cm45 | LYS 39 | 1.32x32 | HBAcceptor |
| SER 4 | NTc.Cm45 | LYS 39 | 1.32x32 | VdWContact |
| SER 4 | NTc.Cm45 | SER 184 | - | VdWContact |
| ALA 5 | NTc.Cm44 | THR 34 | - | Hydrophobic |
| ALA 5 | NTc.Cm44 | THR 34 | - | VdWContact |
| VAL 6 | NTc.Cm43 | SER 98 | 2.63x63 | VdWContact |
| VAL 6 | NTc.Cm43 | LYS 99 | 2.64x64 | Hydrophobic |
| VAL 6 | NTc.Cm43 | LYS 99 | 2.64x64 | VdWContact |
| VAL 6 | NTc.Cm43 | GLY 102 | 23.49x49 | VdWContact |
| LEU 7 | NTc.Cm42 | LEU 32 | - | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 32 | - | VdWContact |
| LEU 7 | NTc.Cm42 | VAL 186 | - | Hydrophobic |
| THR 8 | NTc.Cm41 | LEU 287 | 7.35x34 | Hydrophobic |
| THR 8 | NTc.Cm41 | ASP 288 | 7.36x35 | VdWContact |
| GLU 9 | NTc.Cm40 | TYR 188 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 199 | 5.35x36 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 199 | 5.35x36 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 199 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 203 | 5.39x40 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 203 | 5.39x40 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 203 | 5.39x40 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 269 | 6.62x62 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 269 | 6.62x62 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 269 | 6.62x62 | VdWContact |
| GLU 9 | NTc.Cm40 | LEU 287 | 7.35x34 | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 178 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | PRO 180 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | PRO 180 | - | VdWContact |
| LEU 10 | NTc.Cm39 | VAL 186 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 188 | 45.51x51 | HBDonor |
| LEU 10 | NTc.Cm39 | TYR 188 | 45.51x51 | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 188 | 45.51x51 | VdWContact |
| LEU 10 | NTc.Cm39 | ARG 269 | 6.62x62 | HBAcceptor |
| LEU 10 | NTc.Cm39 | ARG 269 | 6.62x62 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 265 | 6.58x58 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 265 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 265 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | MET 268 | 6.61x61 | VdWContact |
| ARG 11 | NTc.Cm38 | GLU 275 | - | Cationic |
| ARG 11 | NTc.Cm38 | ARG 280 | 7.28x27 | VdWContact |
| CYS 12 | NTc.Cm37 | ARG 280 | 7.28x27 | HBAcceptor |
| CYS 12 | NTc.Cm37 | ARG 280 | 7.28x27 | VdWContact |
| THR 13 | NTc.Cm36 | PRO 29 | - | Hydrophobic |
| THR 13 | NTc.Cm36 | PRO 29 | - | VdWContact |
| THR 13 | NTc.Cm36 | CYS 30 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 30 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 30 | - | VdWContact |
| LEU 15 | NTc.Cm34 | GLU 275 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | GLU 275 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 277 | 7.25x24 | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 277 | 7.25x24 | VdWContact |
| LEU 15 | NTc.Cm34 | ARG 280 | 7.28x27 | VdWContact |
| ARG 16 | NTc.Cm33 | ASP 26 | - | Cationic |
| ARG 16 | NTc.Cm33 | ASP 26 | - | VdWContact |
| ARG 16 | NTc.Cm33 | TYR 27 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | PRO 21 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | PRO 21 | - | VdWContact |
| THR 18 | NTc.Cm31 | TYR 27 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm29 | PRO 21 | - | VdWContact |
| VAL 21 | NTc.Cm28 | PRO 21 | - | VdWContact |
| PRO 23 | NTc.Cm26 | TRP 10 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | PHE 12 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | PHE 17 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | ASP 13 | - | Cationic |
| ILE 26 | NTc.Cm23 | TRP 10 | - | Hydrophobic |
| ILE 26 | NTc.Cm23 | TRP 10 | - | VdWContact |
| LYS 28 | NTc.Cm21 | ASN 3 | - | VdWContact |
| LYS 28 | NTc.Cm21 | THR 5 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | ASN 3 | - | VdWContact |
| LEU 29 | NTc.Cm20 | ILE 4 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | ILE 4 | - | HBDonor |
| LEU 29 | NTc.Cm20 | ILE 4 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | ILE 4 | - | VdWContact |
| LEU 29 | NTc.Cm20 | TRP 10 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | TRP 10 | - | VdWContact |
| GLN 30 | NTc.Cm19 | MET 1 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | MET 1 | - | VdWContact |
| GLN 30 | NTc.Cm19 | ASN 3 | - | VdWContact |
| VAL 31 | NTc.Cm18 | MET 1 | - | VdWContact |
| VAL 31 | NTc.Cm18 | SER 2 | - | HBDonor |
| VAL 31 | NTc.Cm18 | SER 2 | - | VdWContact |
| PHE 32 | NTc.Cm17 | MET 1 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | MET 1 | - | VdWContact |
| PHE 32 | NTc.Cm17 | ASN 181 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | ASN 181 | - | VdWContact |
| PHE 32 | NTc.Cm17 | ASN 182 | - | VdWContact |
| GLY 35 | NTc.Cm14 | ASN 193 | - | VdWContact |
| PRO 36 | NTc.Cm13 | TYR 178 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | VAL 190 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | VAL 190 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLY 192 | - | VdWContact |
| PRO 36 | NTc.Cm13 | THR 195 | 5.31x32 | Hydrophobic |
| PRO 36 | NTc.Cm13 | THR 195 | 5.31x32 | VdWContact |
| GLN 37 | NTc.Cm12 | TYR 178 | - | Hydrophobic |
| GLN 37 | NTc.Cm12 | ASN 181 | - | HBAcceptor |
| GLN 37 | NTc.Cm12 | ASN 181 | - | VdWContact |
| SER 39 | NTc.Cm10 | ASN 193 | - | VdWContact |
| VAL 44 | NTc.Cm5 | PRO 29 | - | Hydrophobic |
| GLN 52 | cxb1.1 | SER 28 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 29 | - | Hydrophobic |
| VAL 53 | cxb1.2 | TYR 27 | - | Hydrophobic |
| CYS 54 | cxb1.5 | TYR 27 | - | HBDonor |
| CYS 54 | cxb1.5 | TYR 27 | - | VdWContact |
| PRO 60 | cxb1.15 | PHE 17 | - | Hydrophobic |
| PHE 61 | cxb1.16 | PHE 17 | - | Hydrophobic |
| PHE 61 | cxb1.16 | PHE 17 | - | VdWContact |
| LYS 64 | B1.3 | PHE 12 | - | Hydrophobic |
| LYS 64 | B1.3 | LEU 15 | - | Hydrophobic |
| LYS 64 | B1.3 | LEU 15 | - | VdWContact |
| VAL 65 | B1.4 | ILE 4 | - | Hydrophobic |
| VAL 65 | B1.4 | TRP 10 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 12 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 12 | - | VdWContact |
| LYS 68 | B1.7 | ASP 11 | - | VdWContact |
| LYS 68 | B1.7 | PHE 12 | - | CationPi |
| LYS 68 | B1.7 | PHE 12 | - | Hydrophobic |
| LYS 68 | B1.7 | PHE 12 | - | VdWContact |
| ILE 69 | b1b2.4 | ILE 4 | - | Hydrophobic |
| ILE 69 | b1b2.4 | ILE 4 | - | VdWContact |
| ILE 69 | b1b2.4 | MET 9 | - | Hydrophobic |
| ILE 69 | b1b2.4 | MET 9 | - | VdWContact |
