Predicted complex interactions
CXCL13_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 78
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm32 | ASP 179 | 4.60x61 | Cationic |
| VAL 1 | NTc.Cm32 | VAL 183 | 4.64x65 | Hydrophobic |
| VAL 1 | NTc.Cm32 | VAL 183 | 4.64x65 | VdWContact |
| VAL 1 | NTc.Cm32 | HIS 196 | 45.51x51 | Hydrophobic |
| VAL 1 | NTc.Cm32 | HIS 196 | 45.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 53 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 53 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 102 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 102 | 2.60x60 | VdWContact |
| GLU 3 | NTc.Cm30 | ARG 211 | 5.39x40 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 211 | 5.39x40 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 211 | 5.39x40 | VdWContact |
| GLU 3 | NTc.Cm30 | LEU 270 | 6.55x55 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LEU 294 | 7.35x34 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LEU 294 | 7.35x34 | VdWContact |
| GLU 3 | NTc.Cm30 | GLU 298 | 7.39x38 | HBDonor |
| GLU 3 | NTc.Cm30 | GLU 298 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm29 | LEU 49 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | VAL 106 | 2.64x64 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLN 295 | 7.36x35 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TRP 102 | 2.60x60 | Hydrophobic |
| TYR 5 | NTc.Cm28 | SER 105 | 2.63x63 | HBAcceptor |
| TYR 5 | NTc.Cm28 | SER 105 | 2.63x63 | HBDonor |
| TYR 5 | NTc.Cm28 | SER 105 | 2.63x63 | VdWContact |
| TYR 5 | NTc.Cm28 | VAL 106 | 2.64x64 | Hydrophobic |
| TYR 5 | NTc.Cm28 | ASN 194 | - | Hydrophobic |
| TYR 5 | NTc.Cm28 | HIS 196 | 45.51x51 | Hydrophobic |
| TYR 6 | NTc.Cm27 | ALA 197 | 45.52x52 | VdWContact |
| THR 7 | NTc.Cm26 | ASP 291 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 291 | 7.32x31 | VdWContact |
| LEU 9 | NTc.Cm24 | HIS 196 | 45.51x51 | Hydrophobic |
| LEU 9 | NTc.Cm24 | HIS 196 | 45.51x51 | VdWContact |
| ARG 10 | NTc.Cm23 | HIS 273 | 6.58x58 | CationPi |
| ARG 10 | NTc.Cm23 | HIS 273 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 277 | 6.62x62 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 291 | 7.32x31 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 291 | 7.32x31 | HBDonor |
| ARG 10 | NTc.Cm23 | ASP 291 | 7.32x31 | VdWContact |
| ARG 10 | NTc.Cm23 | LEU 294 | 7.35x34 | VdWContact |
| ARG 12 | NTc.Cm21 | LEU 35 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | LEU 35 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 36 | - | VdWContact |
| VAL 14 | NTc.Cm19 | MET 34 | - | HBDonor |
| VAL 14 | NTc.Cm19 | MET 34 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | CYS 36 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 284 | 7.25x24 | Hydrophobic |
| VAL 14 | NTc.Cm19 | CYS 284 | 7.25x24 | VdWContact |
| GLN 15 | NTc.Cm18 | MET 34 | - | Hydrophobic |
| ASN 36 | cxb1.1 | ASP 198 | - | HBDonor |
| ASN 36 | cxb1.1 | ASP 198 | - | VdWContact |
| ASN 36 | cxb1.1 | PHE 199 | - | HBAcceptor |
| ASN 36 | cxb1.1 | PHE 199 | - | VdWContact |
| ASN 36 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| PRO 39 | cxb1.6 | THR 204 | 5.32x33 | Hydrophobic |
| PRO 39 | cxb1.6 | THR 204 | 5.32x33 | VdWContact |
| PRO 39 | cxb1.6 | ASP 277 | 6.62x62 | VdWContact |
| PRO 39 | cxb1.6 | GLN 279 | 6.64x64 | VdWContact |
| ARG 40 | cxb1.7 | GLN 279 | 6.64x64 | HBDonor |
| ARG 40 | cxb1.7 | GLN 279 | 6.64x64 | VdWContact |
| ILE 44 | cxb1.14 | LEU 35 | - | Hydrophobic |
| ILE 44 | cxb1.14 | LEU 35 | - | VdWContact |
| LYS 47 | B1.1 | LEU 28 | - | VdWContact |
| ILE 52 | B1.6 | ALA 32 | - | HBDonor |
| ILE 52 | B1.6 | ALA 32 | - | VdWContact |
| ILE 52 | B1.6 | PHE 33 | - | Hydrophobic |
| ILE 52 | B1.6 | LEU 35 | - | Hydrophobic |
| ILE 52 | B1.6 | LEU 35 | - | VdWContact |
| VAL 53 | B1.7 | VAL 31 | - | Hydrophobic |
| VAL 53 | B1.7 | MET 34 | - | Hydrophobic |
| CYS 54 | b1b2.4 | MET 34 | - | Hydrophobic |
| PHE 82 | H.1 | LYS 190 | - | Hydrophobic |
| PHE 82 | H.1 | LYS 190 | - | VdWContact |
| ARG 84 | H.3 | HIS 186 | - | VdWContact |
| ARG 84 | H.3 | GLU 187 | - | HBDonor |
| ARG 84 | H.3 | GLU 187 | - | VdWContact |
