Predicted complex interactions
CCL1_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm32 | LYS 126 | 3.32x32 | VdWContact |
| LYS 1 | NTc.Cm32 | GLU 127 | 3.33x33 | Cationic |
| LYS 1 | NTc.Cm32 | GLU 127 | 3.33x33 | VdWContact |
| LYS 1 | NTc.Cm32 | PRO 215 | 5.42x43 | VdWContact |
| LYS 1 | NTc.Cm32 | TYR 267 | 6.51x51 | HBAcceptor |
| LYS 1 | NTc.Cm32 | GLU 300 | 7.39x38 | Cationic |
| LYS 1 | NTc.Cm32 | GLU 300 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm31 | ARG 184 | 4.64x65 | HBAcceptor |
| SER 2 | NTc.Cm31 | GLU 300 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm30 | ARG 208 | 5.35x36 | HBAcceptor |
| MET 3 | NTc.Cm30 | ARG 208 | 5.35x36 | VdWContact |
| MET 3 | NTc.Cm30 | ARG 212 | 5.39x40 | Hydrophobic |
| MET 3 | NTc.Cm30 | ARG 212 | 5.39x40 | VdWContact |
| MET 3 | NTc.Cm30 | TYR 267 | 6.51x51 | VdWContact |
| MET 3 | NTc.Cm30 | LEU 271 | 6.55x55 | Hydrophobic |
| MET 3 | NTc.Cm30 | LEU 271 | 6.55x55 | VdWContact |
| MET 3 | NTc.Cm30 | LEU 296 | 7.35x34 | Hydrophobic |
| GLN 4 | NTc.Cm29 | LYS 108 | 2.64x64 | HBAcceptor |
| GLN 4 | NTc.Cm29 | LYS 108 | 2.64x64 | VdWContact |
| GLN 4 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| GLN 4 | NTc.Cm29 | ASP 297 | 7.36x35 | HBDonor |
| GLN 4 | NTc.Cm29 | ASP 297 | 7.36x35 | VdWContact |
| VAL 5 | NTc.Cm28 | ARG 278 | 6.62x62 | VdWContact |
| PRO 6 | NTc.Cm27 | ALA 195 | - | Hydrophobic |
| PRO 6 | NTc.Cm27 | ALA 195 | - | VdWContact |
| PRO 6 | NTc.Cm27 | TYR 197 | 45.51x51 | Hydrophobic |
| PRO 6 | NTc.Cm27 | TYR 197 | 45.51x51 | VdWContact |
| PHE 7 | NTc.Cm26 | PRO 41 | - | Hydrophobic |
| PHE 7 | NTc.Cm26 | PRO 41 | - | VdWContact |
| PHE 7 | NTc.Cm26 | VAL 192 | - | Hydrophobic |
| PHE 7 | NTc.Cm26 | VAL 192 | - | VdWContact |
| ARG 9 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| ARG 9 | NTc.Cm24 | PRO 38 | - | VdWContact |
| ARG 9 | NTc.Cm24 | CYS 39 | - | VdWContact |
| ARG 9 | NTc.Cm24 | GLU 40 | - | Cationic |
| ARG 9 | NTc.Cm24 | GLU 40 | - | HBDonor |
| ARG 9 | NTc.Cm24 | GLU 40 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 39 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 39 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 39 | - | VdWContact |
| PHE 12 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | GLU 284 | - | VdWContact |
| PHE 12 | NTc.Cm21 | ARG 289 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm20 | ASP 35 | - | HBDonor |
| SER 13 | NTc.Cm20 | ASP 35 | - | VdWContact |
| ALA 15 | NTc.Cm18 | LEU 33 | - | Hydrophobic |
| ALA 15 | NTc.Cm18 | ALA 36 | - | Hydrophobic |
| GLN 17 | NTc.Cm16 | PHE 32 | - | Hydrophobic |
| GLN 17 | NTc.Cm16 | PHE 32 | - | VdWContact |
| ILE 19 | NTc.Cm14 | PHE 32 | - | Hydrophobic |
| ILE 19 | NTc.Cm14 | LEU 33 | - | Hydrophobic |
| ILE 19 | NTc.Cm14 | LEU 33 | - | VdWContact |
| PRO 20 | NTc.Cm13 | LEU 20 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | LEU 20 | - | VdWContact |
| ARG 22 | NTc.Cm11 | ASP 19 | - | Cationic |
| ARG 22 | NTc.Cm11 | ASP 19 | - | HBDonor |
| ARG 22 | NTc.Cm11 | ASP 19 | - | VdWContact |
| ARG 22 | NTc.Cm11 | LEU 20 | - | VdWContact |
| ARG 22 | NTc.Cm11 | SER 21 | - | VdWContact |
| SER 32 | NTc.Cm1 | GLY 201 | - | HBDonor |
| SER 32 | NTc.Cm1 | GLY 201 | - | VdWContact |
| SER 32 | NTc.Cm1 | ASN 202 | - | VdWContact |
| SER 32 | NTc.Cm1 | THR 204 | 5.31x32 | VdWContact |
| SER 32 | NTc.Cm1 | ALA 205 | 5.32x33 | HBAcceptor |
| SER 32 | NTc.Cm1 | ALA 205 | 5.32x33 | VdWContact |
| ILE 33 | CX.1 | VAL 187 | - | Hydrophobic |
| ILE 33 | CX.1 | TYR 197 | 45.51x51 | Hydrophobic |
| ILE 33 | CX.1 | TYR 197 | 45.51x51 | VdWContact |
| ILE 33 | CX.1 | THR 204 | 5.31x32 | Hydrophobic |
| ILE 33 | CX.1 | ARG 278 | 6.62x62 | HBAcceptor |
| ILE 33 | CX.1 | ARG 278 | 6.62x62 | VdWContact |
| SER 35 | cxb1.1 | GLU 284 | - | HBDonor |
| SER 35 | cxb1.1 | GLU 284 | - | VdWContact |
| ILE 40 | cxb1.8 | PRO 38 | - | Hydrophobic |
| LEU 43 | cxb1.14 | LEU 29 | - | Hydrophobic |
| LEU 43 | cxb1.14 | LEU 29 | - | VdWContact |
| LEU 43 | cxb1.14 | LEU 33 | - | Hydrophobic |
| ARG 45 | cxb1.16 | TYR 23 | - | VdWContact |
| ARG 45 | cxb1.16 | SER 24 | - | HBDonor |
| ARG 45 | cxb1.16 | SER 24 | - | VdWContact |
| ARG 45 | cxb1.16 | SER 26 | - | HBDonor |
| ARG 45 | cxb1.16 | SER 26 | - | VdWContact |
| ARG 45 | cxb1.16 | SER 27 | - | VdWContact |
| LYS 47 | B1.2 | LEU 29 | - | Hydrophobic |
| LYS 47 | B1.2 | LEU 29 | - | VdWContact |
| GLU 48 | B1.3 | ALA 37 | - | VdWContact |
| GLU 48 | B1.3 | PRO 38 | - | Hydrophobic |
| ALA 49 | B1.4 | LEU 33 | - | Hydrophobic |
| CYS 50 | B1.5 | ALA 36 | - | HBDonor |
| CYS 50 | B1.5 | ALA 36 | - | VdWContact |
| CYS 50 | B1.5 | PRO 38 | - | VdWContact |
| LYS 71 | B3.1 | ASN 191 | - | HBDonor |
| LYS 71 | B3.1 | ASN 191 | - | VdWContact |
