Predicted complex interactions
CCL16_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 110
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 2 | NTc.Cm35 | VAL 187 | - | Hydrophobic |
| PRO 2 | NTc.Cm35 | VAL 187 | - | VdWContact |
| PRO 2 | NTc.Cm35 | TYR 188 | - | VdWContact |
| LYS 3 | NTc.Cm34 | ASP 199 | - | VdWContact |
| LYS 3 | NTc.Cm34 | GLY 201 | - | VdWContact |
| LYS 3 | NTc.Cm34 | ASN 202 | - | HBDonor |
| LYS 3 | NTc.Cm34 | ASN 202 | - | VdWContact |
| VAL 4 | NTc.Cm33 | VAL 187 | - | Hydrophobic |
| VAL 4 | NTc.Cm33 | VAL 187 | - | VdWContact |
| VAL 4 | NTc.Cm33 | SER 189 | - | VdWContact |
| VAL 4 | NTc.Cm33 | TYR 197 | 45.51x51 | Hydrophobic |
| VAL 4 | NTc.Cm33 | TYR 197 | 45.51x51 | VdWContact |
| PRO 5 | NTc.Cm32 | VAL 187 | - | Hydrophobic |
| PRO 5 | NTc.Cm32 | VAL 187 | - | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 197 | 45.51x51 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 197 | 45.51x51 | VdWContact |
| PRO 5 | NTc.Cm32 | GLU 198 | 45.52x52 | VdWContact |
| PRO 5 | NTc.Cm32 | ASP 199 | - | Hydrophobic |
| PRO 5 | NTc.Cm32 | ASP 199 | - | VdWContact |
| GLU 6 | NTc.Cm31 | TYR 197 | 45.51x51 | Hydrophobic |
| GLU 6 | NTc.Cm31 | TYR 197 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm31 | THR 204 | 5.31x32 | Hydrophobic |
| GLU 6 | NTc.Cm31 | ALA 205 | 5.32x33 | VdWContact |
| GLU 6 | NTc.Cm31 | ARG 208 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 6 | NTc.Cm31 | ARG 208 | 5.35x36 | VdWContact |
| GLU 6 | NTc.Cm31 | ARG 278 | 6.62x62 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 278 | 6.62x62 | VdWContact |
| TRP 7 | NTc.Cm30 | TRP 104 | 2.60x60 | Hydrophobic |
| TRP 7 | NTc.Cm30 | ARG 184 | 4.64x65 | Hydrophobic |
| TRP 7 | NTc.Cm30 | ARG 184 | 4.64x65 | VdWContact |
| TRP 7 | NTc.Cm30 | CYS 196 | 45.50x50 | VdWContact |
| TRP 7 | NTc.Cm30 | TYR 197 | 45.51x51 | Hydrophobic |
| TRP 7 | NTc.Cm30 | TYR 197 | 45.51x51 | PiStacking |
| TRP 7 | NTc.Cm30 | TYR 197 | 45.51x51 | VdWContact |
| TRP 7 | NTc.Cm30 | GLU 198 | 45.52x52 | HBDonor |
| TRP 7 | NTc.Cm30 | GLU 198 | 45.52x52 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLU 198 | 45.52x52 | VdWContact |
| TRP 7 | NTc.Cm30 | ARG 208 | 5.35x36 | VdWContact |
| VAL 8 | NTc.Cm29 | TYR 197 | 45.51x51 | HBAcceptor |
| VAL 8 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| VAL 8 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| ASN 9 | NTc.Cm28 | ARG 289 | 7.28x27 | HBAcceptor |
| ASN 9 | NTc.Cm28 | ARG 289 | 7.28x27 | VdWContact |
| ASN 9 | NTc.Cm28 | ASP 293 | 7.32x31 | Hydrophobic |
| ASN 9 | NTc.Cm28 | ASP 293 | 7.32x31 | VdWContact |
| ASN 9 | NTc.Cm28 | LEU 296 | 7.35x34 | VdWContact |
| THR 10 | NTc.Cm27 | ALA 195 | - | Hydrophobic |
| THR 10 | NTc.Cm27 | TYR 197 | 45.51x51 | Hydrophobic |
| THR 10 | NTc.Cm27 | TYR 197 | 45.51x51 | VdWContact |
| PRO 11 | NTc.Cm26 | PRO 41 | - | Hydrophobic |
| PRO 11 | NTc.Cm26 | PRO 41 | - | VdWContact |
| THR 13 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | PRO 38 | - | VdWContact |
| THR 13 | NTc.Cm24 | CYS 39 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 39 | - | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 39 | - | VdWContact |
| LEU 16 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | GLU 284 | - | VdWContact |
| LEU 16 | NTc.Cm21 | THR 285 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 286 | 7.25x24 | VdWContact |
| LYS 17 | NTc.Cm20 | ASP 35 | - | Cationic |
| LYS 17 | NTc.Cm20 | ASP 35 | - | Hydrophobic |
| LYS 17 | NTc.Cm20 | ASP 35 | - | VdWContact |
| TYR 19 | NTc.Cm18 | PHE 32 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | PHE 32 | - | VdWContact |
| TYR 19 | NTc.Cm18 | LEU 33 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | ALA 36 | - | Hydrophobic |
| LYS 21 | NTc.Cm16 | PHE 11 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | TRP 15 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TRP 15 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TRP 15 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TRP 15 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TRP 15 | - | VdWContact |
| LEU 27 | NTc.Cm10 | LEU 20 | - | Hydrophobic |
| HIS 38 | CX.5 | ARG 278 | 6.62x62 | Hydrophobic |
| HIS 38 | CX.5 | ARG 278 | 6.62x62 | VdWContact |
| HIS 38 | CX.5 | GLN 280 | 6.64x64 | Hydrophobic |
| HIS 38 | CX.5 | GLN 280 | 6.64x64 | VdWContact |
| HIS 38 | CX.5 | GLU 284 | - | HBDonor |
| HIS 38 | CX.5 | GLU 284 | - | VdWContact |
| ILE 43 | cxb1.7 | PRO 38 | - | Hydrophobic |
| ARG 48 | cxb1.15 | TYR 23 | - | VdWContact |
| ARG 50 | B1.1 | LEU 29 | - | Hydrophobic |
| ARG 50 | B1.1 | LEU 29 | - | VdWContact |
| GLU 51 | B1.2 | ALA 37 | - | VdWContact |
| GLU 51 | B1.2 | PRO 38 | - | Hydrophobic |
| VAL 52 | B1.3 | LEU 33 | - | Hydrophobic |
| CYS 53 | B1.4 | ALA 36 | - | HBDonor |
| CYS 53 | B1.4 | ALA 36 | - | VdWContact |
| CYS 53 | B1.4 | PRO 38 | - | VdWContact |
| PRO 74 | B3.1 | SER 190 | - | VdWContact |
| PRO 74 | B3.1 | ASN 191 | - | Hydrophobic |
| PRO 74 | B3.1 | ASN 191 | - | VdWContact |
| THR 75 | B3.2 | SER 189 | - | VdWContact |
| THR 75 | B3.2 | SER 190 | - | HBDonor |
| THR 75 | B3.2 | SER 190 | - | VdWContact |
| THR 75 | B3.2 | ASN 191 | - | VdWContact |
| THR 75 | B3.2 | VAL 192 | - | VdWContact |
| ARG 76 | B3.3 | GLU 40 | - | Cationic |
| ARG 76 | B3.3 | GLU 40 | - | HBDonor |
| ARG 76 | B3.3 | GLU 40 | - | VdWContact |
| ASN 77 | B3.4 | ASN 191 | - | HBDonor |
| ASN 77 | B3.4 | ASN 191 | - | Hydrophobic |
| ASN 77 | B3.4 | ASN 191 | - | VdWContact |
| ASN 77 | B3.4 | VAL 192 | - | VdWContact |
| LEU 78 | b3h.1 | PRO 41 | - | Hydrophobic |
| LEU 78 | b3h.1 | PRO 41 | - | VdWContact |
| LEU 78 | b3h.1 | SER 43 | - | VdWContact |
