Predicted complex interactions
CCL18_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 65
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 6 | NTc.Cm24 | ASN 191 | - | Hydrophobic |
| LYS 7 | NTc.Cm23 | GLU 40 | - | Cationic |
| LYS 7 | NTc.Cm23 | GLU 40 | - | HBDonor |
| LYS 7 | NTc.Cm23 | GLU 40 | - | Hydrophobic |
| LYS 7 | NTc.Cm23 | GLU 40 | - | VdWContact |
| GLU 8 | NTc.Cm22 | PRO 41 | - | VdWContact |
| GLU 8 | NTc.Cm22 | VAL 192 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | VAL 192 | - | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 38 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | PRO 38 | - | VdWContact |
| LEU 9 | NTc.Cm21 | GLU 40 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | CYS 39 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 39 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 39 | - | VdWContact |
| CYS 10 | NTc.Cm20 | PRO 41 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 39 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 39 | - | VdWContact |
| LEU 12 | NTc.Cm18 | GLU 284 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | GLU 284 | - | VdWContact |
| LEU 12 | NTc.Cm18 | ARG 289 | 7.28x27 | Hydrophobic |
| LEU 12 | NTc.Cm18 | ARG 289 | 7.28x27 | VdWContact |
| TRP 17 | NTc.Cm13 | PHE 11 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | PHE 32 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | PHE 32 | - | VdWContact |
| TRP 17 | NTc.Cm13 | LEU 33 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | LEU 33 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TRP 15 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TRP 15 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TRP 15 | - | VdWContact |
| PRO 32 | cxb1.1 | VAL 187 | - | Hydrophobic |
| PRO 32 | cxb1.1 | VAL 187 | - | VdWContact |
| PRO 32 | cxb1.1 | TYR 197 | 45.51x51 | VdWContact |
| PRO 32 | cxb1.1 | ARG 208 | 5.35x36 | HBAcceptor |
| PRO 32 | cxb1.1 | ARG 208 | 5.35x36 | VdWContact |
| GLN 33 | cxb1.2 | ALA 195 | - | Hydrophobic |
| GLN 33 | cxb1.2 | ALA 195 | - | VdWContact |
| GLN 33 | cxb1.2 | TYR 197 | 45.51x51 | HBAcceptor |
| GLN 33 | cxb1.2 | TYR 197 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | TYR 197 | 45.51x51 | VdWContact |
| CYS 34 | cxb1.5 | ARG 208 | 5.35x36 | HBAcceptor |
| CYS 34 | cxb1.5 | ARG 208 | 5.35x36 | VdWContact |
| PRO 35 | cxb1.6 | ARG 278 | 6.62x62 | HBAcceptor |
| PRO 35 | cxb1.6 | ARG 278 | 6.62x62 | VdWContact |
| LYS 36 | cxb1.7 | ALA 205 | 5.32x33 | Hydrophobic |
| LYS 36 | cxb1.7 | GLU 284 | - | Cationic |
| LYS 36 | cxb1.7 | GLU 284 | - | VdWContact |
| PRO 37 | cxb1.8 | ASN 202 | - | VdWContact |
| ILE 40 | cxb1.14 | PRO 38 | - | Hydrophobic |
| ARG 45 | B1.3 | SER 26 | - | HBDonor |
| ARG 45 | B1.3 | SER 26 | - | VdWContact |
| ARG 47 | B1.5 | SER 27 | - | HBDonor |
| ARG 47 | B1.5 | SER 27 | - | VdWContact |
| ARG 47 | B1.5 | THR 28 | - | HBDonor |
| ARG 47 | B1.5 | THR 28 | - | VdWContact |
| ARG 47 | B1.5 | LEU 29 | - | Hydrophobic |
| ARG 47 | B1.5 | LEU 29 | - | VdWContact |
| GLN 48 | B1.6 | PRO 38 | - | Hydrophobic |
| ILE 49 | B1.7 | LEU 29 | - | Hydrophobic |
| ILE 49 | B1.7 | LEU 33 | - | Hydrophobic |
| ILE 49 | B1.7 | LEU 33 | - | VdWContact |
| ILE 49 | B1.7 | ALA 36 | - | Hydrophobic |
| CYS 50 | b1b2.4 | ALA 36 | - | HBDonor |
| CYS 50 | b1b2.4 | ALA 36 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 38 | - | VdWContact |
| ASN 54 | b1b2.12 | ASN 202 | - | VdWContact |
