Predicted complex interactions
CCL19_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 61
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 300 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 300 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 300 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | LYS 108 | 2.64x64 | VdWContact |
| THR 2 | NTc.Cm27 | TYR 197 | 45.51x51 | VdWContact |
| ASN 3 | NTc.Cm26 | TYR 197 | 45.51x51 | VdWContact |
| ASN 3 | NTc.Cm26 | ARG 212 | 5.39x40 | HBAcceptor |
| ASN 3 | NTc.Cm26 | ARG 212 | 5.39x40 | VdWContact |
| ASN 3 | NTc.Cm26 | ASP 274 | 6.58x58 | HBDonor |
| ASN 3 | NTc.Cm26 | ASP 274 | 6.58x58 | VdWContact |
| ASN 3 | NTc.Cm26 | ARG 278 | 6.62x62 | VdWContact |
| ASN 3 | NTc.Cm26 | LEU 296 | 7.35x34 | Hydrophobic |
| ASP 4 | NTc.Cm25 | ALA 195 | - | Hydrophobic |
| ASP 4 | NTc.Cm25 | ALA 195 | - | VdWContact |
| ALA 5 | NTc.Cm24 | TYR 197 | 45.51x51 | VdWContact |
| ALA 5 | NTc.Cm24 | ARG 278 | 6.62x62 | VdWContact |
| ALA 5 | NTc.Cm24 | ARG 289 | 7.28x27 | HBAcceptor |
| ALA 5 | NTc.Cm24 | ARG 289 | 7.28x27 | VdWContact |
| GLU 6 | NTc.Cm23 | SER 189 | - | VdWContact |
| GLU 6 | NTc.Cm23 | ARG 289 | 7.28x27 | HBAcceptor |
| GLU 6 | NTc.Cm23 | ARG 289 | 7.28x27 | VdWContact |
| ASP 7 | NTc.Cm22 | PRO 41 | - | VdWContact |
| CYS 8 | NTc.Cm21 | ARG 289 | 7.28x27 | Anionic |
| CYS 8 | NTc.Cm21 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 8 | NTc.Cm21 | ARG 289 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 39 | - | VdWContact |
| LEU 10 | NTc.Cm19 | GLU 284 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | GLU 284 | - | VdWContact |
| SER 11 | NTc.Cm18 | ASP 35 | - | HBDonor |
| SER 11 | NTc.Cm18 | ASP 35 | - | VdWContact |
| SER 11 | NTc.Cm18 | ALA 36 | - | VdWContact |
| THR 13 | NTc.Cm16 | LEU 33 | - | Hydrophobic |
| THR 13 | NTc.Cm16 | LEU 33 | - | VdWContact |
| THR 13 | NTc.Cm16 | ALA 36 | - | VdWContact |
| LYS 15 | NTc.Cm14 | PHE 32 | - | CationPi |
| LYS 15 | NTc.Cm14 | PHE 32 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | PHE 32 | - | VdWContact |
| ILE 17 | NTc.Cm12 | LEU 33 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 23 | - | Hydrophobic |
| ILE 30 | CX.5 | ASN 202 | - | Hydrophobic |
| ILE 30 | CX.5 | ASN 202 | - | VdWContact |
| LYS 31 | cxb1.1 | GLY 201 | - | VdWContact |
| LYS 31 | cxb1.1 | ASN 202 | - | VdWContact |
| ARG 35 | cxb1.8 | GLN 280 | 6.64x64 | VdWContact |
| ARG 35 | cxb1.8 | GLU 284 | - | Cationic |
| VAL 40 | cxb1.15 | PRO 38 | - | Hydrophobic |
| THR 43 | B1.2 | LEU 29 | - | Hydrophobic |
| ARG 45 | B1.4 | SER 27 | - | VdWContact |
| ARG 47 | B1.6 | LEU 29 | - | VdWContact |
| GLN 48 | B1.7 | ALA 37 | - | VdWContact |
| GLN 48 | B1.7 | PRO 38 | - | Hydrophobic |
| GLN 48 | B1.7 | PRO 38 | - | VdWContact |
| LEU 49 | b1b2.4 | LEU 29 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 29 | - | VdWContact |
| LEU 49 | b1b2.4 | LEU 33 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 33 | - | VdWContact |
| LEU 49 | b1b2.4 | ALA 36 | - | VdWContact |
| CYS 50 | b1b2.6 | ALA 36 | - | HBDonor |
| CYS 50 | b1b2.6 | ALA 36 | - | VdWContact |
| CYS 50 | b1b2.6 | PRO 38 | - | VdWContact |
| ARG 60 | B2.2 | PHE 14 | - | VdWContact |
