Predicted complex interactions
CXCL14_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 18 | NTc.Cm19 | ASN 188 | - | HBAcceptor |
| LYS 18 | NTc.Cm19 | ASN 188 | - | VdWContact |
| LYS 19 | NTc.Cm18 | ARG 37 | - | VdWContact |
| LEU 20 | NTc.Cm17 | LEU 35 | - | Hydrophobic |
| LEU 20 | NTc.Cm17 | LEU 35 | - | VdWContact |
| GLU 21 | NTc.Cm16 | LEU 35 | - | Hydrophobic |
| GLU 21 | NTc.Cm16 | LEU 35 | - | VdWContact |
| GLU 21 | NTc.Cm16 | ARG 37 | - | Anionic |
| GLU 21 | NTc.Cm16 | ARG 37 | - | HBAcceptor |
| GLU 21 | NTc.Cm16 | ARG 37 | - | VdWContact |
| MET 22 | NTc.Cm15 | LEU 28 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | LEU 28 | - | VdWContact |
| MET 22 | NTc.Cm15 | VAL 31 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | VAL 31 | - | VdWContact |
| MET 22 | NTc.Cm15 | ALA 32 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | ALA 32 | - | VdWContact |
| MET 22 | NTc.Cm15 | LEU 35 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | LEU 35 | - | VdWContact |
| GLU 31 | NTc.Cm6 | TYR 24 | - | HBAcceptor |
| GLU 31 | NTc.Cm6 | TYR 24 | - | Hydrophobic |
| GLU 31 | NTc.Cm6 | TYR 24 | - | VdWContact |
| LYS 32 | NTc.Cm5 | LEU 28 | - | Hydrophobic |
| LYS 32 | NTc.Cm5 | LEU 28 | - | VdWContact |
| VAL 34 | NTc.Cm3 | VAL 31 | - | Hydrophobic |
| VAL 34 | NTc.Cm3 | VAL 31 | - | VdWContact |
| LYS 39 | CX.5 | GLU 187 | - | HBDonor |
| LYS 39 | CX.5 | GLU 187 | - | VdWContact |
| LYS 39 | CX.5 | ASN 188 | - | VdWContact |
| VAL 41 | cxb1.2 | LYS 190 | - | Hydrophobic |
| PRO 53 | B1.4 | TYR 27 | - | HBAcceptor |
| PRO 53 | B1.4 | TYR 27 | - | Hydrophobic |
| PRO 53 | B1.4 | TYR 27 | - | VdWContact |
| PRO 53 | B1.4 | VAL 31 | - | Hydrophobic |
| LYS 54 | B1.5 | TYR 24 | - | VdWContact |
| LYS 54 | B1.5 | TYR 27 | - | Hydrophobic |
| LYS 54 | B1.5 | TYR 27 | - | VdWContact |
| LYS 59 | b1b2.7 | TYR 27 | - | CationPi |
| LYS 59 | b1b2.7 | TYR 27 | - | Hydrophobic |
| LYS 59 | b1b2.7 | TYR 27 | - | VdWContact |
| LYS 59 | b1b2.7 | GLU 30 | - | Cationic |
| LYS 59 | b1b2.7 | GLU 30 | - | HBDonor |
| LYS 59 | b1b2.7 | GLU 30 | - | VdWContact |
| ILE 62 | b1b2.10 | VAL 31 | - | Hydrophobic |
| ILE 62 | b1b2.10 | MET 34 | - | Hydrophobic |
| ILE 62 | b1b2.10 | MET 34 | - | VdWContact |
| LYS 63 | b1b2.12 | LEU 278 | 6.63x63 | HBDonor |
| LYS 63 | b1b2.12 | LEU 278 | 6.63x63 | VdWContact |
| LYS 63 | b1b2.12 | GLN 279 | 6.64x64 | HBDonor |
| LYS 63 | b1b2.12 | GLN 279 | 6.64x64 | VdWContact |
| TRP 64 | b1b2.13 | GLY 201 | - | VdWContact |
| TRP 64 | b1b2.13 | HIS 202 | 5.30x31 | VdWContact |
| TRP 64 | b1b2.13 | GLY 203 | 5.31x32 | VdWContact |
| TRP 64 | b1b2.13 | THR 204 | 5.32x33 | Hydrophobic |
| TRP 64 | b1b2.13 | THR 204 | 5.32x33 | VdWContact |
| ASN 66 | b1b2.16 | MET 34 | - | VdWContact |
| ALA 67 | b1b2.17 | THR 204 | 5.32x33 | Hydrophobic |
| ALA 67 | b1b2.17 | THR 204 | 5.32x33 | VdWContact |
| ALA 67 | b1b2.17 | LYS 207 | 5.35x36 | VdWContact |
| TRP 68 | B2.1 | HIS 186 | - | Hydrophobic |
| TRP 68 | B2.1 | ASP 198 | - | HBDonor |
| TRP 68 | B2.1 | ASP 198 | - | VdWContact |
| GLU 70 | B2.3 | LYS 207 | 5.35x36 | Anionic |
| GLU 70 | B2.3 | LYS 207 | 5.35x36 | VdWContact |
| GLU 70 | B2.3 | HIS 273 | 6.58x58 | Hydrophobic |
| GLU 70 | B2.3 | HIS 273 | 6.58x58 | VdWContact |
| GLU 70 | B2.3 | ASP 277 | 6.62x62 | VdWContact |
| LYS 71 | B2.4 | ASP 179 | 4.60x61 | Cationic |
| LYS 71 | B2.4 | ASP 179 | 4.60x61 | VdWContact |
| LYS 71 | B2.4 | HIS 196 | 45.51x51 | Hydrophobic |
| LYS 71 | B2.4 | ALA 197 | 45.52x52 | Hydrophobic |
| LYS 71 | B2.4 | ALA 197 | 45.52x52 | VdWContact |
| ARG 72 | B2.5 | ASN 188 | - | VdWContact |
| ARG 72 | B2.5 | HIS 196 | 45.51x51 | Hydrophobic |
| ARG 72 | B2.5 | HIS 196 | 45.51x51 | VdWContact |
| ARG 73 | B2.6 | PHE 33 | - | CationPi |
| ARG 73 | B2.6 | PHE 33 | - | HBDonor |
| ARG 73 | B2.6 | PHE 33 | - | VdWContact |
| VAL 74 | b2b3.2 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 74 | b2b3.2 | GLN 295 | 7.36x35 | Hydrophobic |
| VAL 74 | b2b3.2 | GLN 295 | 7.36x35 | VdWContact |
| TYR 75 | b2b3.3 | LEU 49 | 1.35x35 | Hydrophobic |
| TYR 75 | b2b3.3 | LEU 49 | 1.35x35 | VdWContact |
| TYR 75 | b2b3.3 | VAL 106 | 2.64x64 | Hydrophobic |
| TYR 75 | b2b3.3 | VAL 106 | 2.64x64 | VdWContact |
| GLU 77 | b2b3.5 | VAL 42 | 1.28x28 | Hydrophobic |
| GLU 77 | b2b3.5 | LYS 46 | 1.32x32 | Anionic |
| GLU 77 | b2b3.5 | LYS 46 | 1.32x32 | HBAcceptor |
| GLU 77 | b2b3.5 | LYS 46 | 1.32x32 | VdWContact |
