Predicted complex interactions
CCL20_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL20_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 77
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm31 | ASP 293 | 7.32x31 | Hydrophobic |
| ALA 1 | NTc.Cm31 | ASP 293 | 7.32x31 | VdWContact |
| ALA 1 | NTc.Cm31 | ASP 297 | 7.36x35 | Cationic |
| ALA 1 | NTc.Cm31 | ASP 297 | 7.36x35 | HBDonor |
| ALA 1 | NTc.Cm31 | ASP 297 | 7.36x35 | VdWContact |
| SER 2 | NTc.Cm30 | TYR 197 | 45.51x51 | VdWContact |
| ASN 3 | NTc.Cm29 | PRO 41 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | SER 189 | - | VdWContact |
| PHE 4 | NTc.Cm28 | VAL 192 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | ALA 195 | - | Hydrophobic |
| ASP 5 | NTc.Cm27 | CYS 39 | - | VdWContact |
| ASP 5 | NTc.Cm27 | GLU 40 | - | VdWContact |
| ASP 5 | NTc.Cm27 | PRO 41 | - | VdWContact |
| CYS 6 | NTc.Cm26 | CYS 39 | - | HBAcceptor |
| CYS 6 | NTc.Cm26 | CYS 39 | - | VdWContact |
| CYS 6 | NTc.Cm26 | ARG 289 | 7.28x27 | Anionic |
| LEU 8 | NTc.Cm24 | CYS 39 | - | VdWContact |
| LEU 8 | NTc.Cm24 | GLU 284 | - | Hydrophobic |
| LEU 8 | NTc.Cm24 | GLU 284 | - | VdWContact |
| LEU 8 | NTc.Cm24 | ARG 289 | 7.28x27 | VdWContact |
| ARG 13 | NTc.Cm19 | PHE 32 | - | VdWContact |
| ILE 14 | NTc.Cm18 | PHE 14 | - | Hydrophobic |
| ILE 14 | NTc.Cm18 | PHE 14 | - | VdWContact |
| ILE 14 | NTc.Cm18 | TRP 15 | - | Hydrophobic |
| ILE 14 | NTc.Cm18 | TRP 15 | - | VdWContact |
| ILE 14 | NTc.Cm18 | GLU 18 | - | VdWContact |
| ILE 14 | NTc.Cm18 | TYR 23 | - | HBAcceptor |
| ILE 14 | NTc.Cm18 | TYR 23 | - | VdWContact |
| LEU 15 | NTc.Cm17 | TRP 15 | - | VdWContact |
| LEU 15 | NTc.Cm17 | TYR 23 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | TYR 23 | - | VdWContact |
| LEU 15 | NTc.Cm17 | LEU 33 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | TRP 15 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | LEU 20 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | LEU 20 | - | VdWContact |
| PRO 17 | NTc.Cm15 | TRP 15 | - | Hydrophobic |
| PRO 17 | NTc.Cm15 | TRP 15 | - | VdWContact |
| PHE 19 | NTc.Cm13 | TYR 25 | - | PiStacking |
| THR 24 | NTc.Cm8 | SER 190 | - | VdWContact |
| ALA 28 | NTc.Cm4 | THR 204 | 5.31x32 | VdWContact |
| ASN 29 | NTc.Cm3 | ASP 199 | - | Hydrophobic |
| ASN 29 | NTc.Cm3 | ASP 199 | - | VdWContact |
| ASN 29 | NTc.Cm3 | GLY 201 | - | VdWContact |
| GLU 30 | NTc.Cm2 | VAL 187 | - | Hydrophobic |
| GLU 30 | NTc.Cm2 | VAL 187 | - | VdWContact |
| GLY 31 | NTc.Cm1 | TYR 197 | 45.51x51 | HBAcceptor |
| GLY 31 | NTc.Cm1 | TYR 197 | 45.51x51 | VdWContact |
| ASP 33 | CX.5 | ALA 205 | 5.32x33 | Hydrophobic |
| ASP 33 | CX.5 | ARG 208 | 5.35x36 | Anionic |
| ASP 33 | CX.5 | ARG 278 | 6.62x62 | Anionic |
| ASP 33 | CX.5 | ARG 278 | 6.62x62 | HBAcceptor |
| ASP 33 | CX.5 | ARG 278 | 6.62x62 | VdWContact |
| ASP 33 | CX.5 | ARG 289 | 7.28x27 | Anionic |
| ASP 33 | CX.5 | ARG 289 | 7.28x27 | HBAcceptor |
| ASP 33 | CX.5 | ARG 289 | 7.28x27 | VdWContact |
| ASN 35 | cxb1.2 | ASN 202 | - | HBDonor |
| ASN 35 | cxb1.2 | ASN 202 | - | VdWContact |
| ILE 38 | cxb1.7 | PRO 38 | - | Hydrophobic |
| LYS 43 | cxb1.15 | SER 26 | - | HBDonor |
| LYS 43 | cxb1.15 | SER 26 | - | VdWContact |
| LYS 43 | cxb1.15 | SER 27 | - | HBDonor |
| LYS 43 | cxb1.15 | SER 27 | - | VdWContact |
| LYS 43 | cxb1.15 | LEU 29 | - | Hydrophobic |
| LYS 43 | cxb1.15 | LEU 29 | - | VdWContact |
| LEU 45 | B1.1 | LEU 29 | - | Hydrophobic |
| LEU 45 | B1.1 | LEU 29 | - | VdWContact |
| SER 46 | B1.2 | ALA 37 | - | VdWContact |
| VAL 47 | B1.3 | LEU 33 | - | Hydrophobic |
| VAL 47 | B1.3 | ALA 36 | - | Hydrophobic |
| CYS 48 | B1.4 | ALA 36 | - | HBDonor |
| CYS 48 | B1.4 | ALA 36 | - | VdWContact |
| CYS 48 | B1.4 | PRO 38 | - | VdWContact |
| TRP 55 | b1b2.8 | PHE 11 | - | Hydrophobic |
| TYR 58 | b1b2.12 | PHE 11 | - | Hydrophobic |
| TYR 58 | b1b2.12 | PHE 11 | - | PiStacking |
| TYR 58 | b1b2.12 | PHE 11 | - | VdWContact |
| ILE 59 | b1b2.13 | TRP 15 | - | Hydrophobic |
