Predicted complex interactions
CCL21_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 104
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | LEU 296 | 7.35x34 | HBDonor |
| SER 1 | NTc.Cm30 | LEU 296 | 7.35x34 | VdWContact |
| SER 1 | NTc.Cm30 | ASP 297 | 7.36x35 | Cationic |
| SER 1 | NTc.Cm30 | ASP 297 | 7.36x35 | VdWContact |
| SER 1 | NTc.Cm30 | GLU 300 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 300 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 300 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | TRP 104 | 2.60x60 | VdWContact |
| ASP 2 | NTc.Cm29 | ARG 184 | 4.64x65 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 184 | 4.64x65 | HBAcceptor |
| ASP 2 | NTc.Cm29 | ARG 184 | 4.64x65 | VdWContact |
| ASP 2 | NTc.Cm29 | CYS 196 | 45.50x50 | VdWContact |
| ASP 2 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| ASP 2 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| ALA 5 | NTc.Cm26 | PRO 41 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | PRO 41 | - | VdWContact |
| GLN 6 | NTc.Cm25 | SER 189 | - | HBAcceptor |
| GLN 6 | NTc.Cm25 | SER 189 | - | VdWContact |
| GLN 6 | NTc.Cm25 | VAL 192 | - | Hydrophobic |
| GLN 6 | NTc.Cm25 | VAL 192 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | CYS 39 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 41 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 39 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 39 | - | VdWContact |
| CYS 8 | NTc.Cm23 | ARG 289 | 7.28x27 | Anionic |
| CYS 8 | NTc.Cm23 | ARG 289 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 39 | - | VdWContact |
| LEU 10 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | GLU 284 | - | VdWContact |
| SER 13 | NTc.Cm18 | LEU 33 | - | VdWContact |
| ARG 15 | NTc.Cm16 | PHE 32 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | PHE 32 | - | VdWContact |
| ARG 15 | NTc.Cm16 | LEU 33 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | LEU 33 | - | VdWContact |
| LYS 16 | NTc.Cm15 | TRP 15 | - | Hydrophobic |
| LYS 16 | NTc.Cm15 | TRP 15 | - | VdWContact |
| LYS 16 | NTc.Cm15 | GLU 18 | - | Cationic |
| LYS 16 | NTc.Cm15 | GLU 18 | - | HBDonor |
| LYS 16 | NTc.Cm15 | GLU 18 | - | VdWContact |
| LYS 16 | NTc.Cm15 | TYR 23 | - | HBAcceptor |
| LYS 16 | NTc.Cm15 | TYR 23 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TRP 15 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 23 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | TYR 23 | - | VdWContact |
| ILE 17 | NTc.Cm14 | LEU 29 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | LEU 29 | - | VdWContact |
| ILE 17 | NTc.Cm14 | LEU 33 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | LEU 20 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | LEU 20 | - | VdWContact |
| PRO 18 | NTc.Cm13 | TYR 23 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 23 | - | VdWContact |
| ALA 19 | NTc.Cm12 | PHE 11 | - | Hydrophobic |
| ALA 19 | NTc.Cm12 | PHE 11 | - | VdWContact |
| LYS 20 | NTc.Cm11 | TYR 23 | - | HBDonor |
| LYS 20 | NTc.Cm11 | TYR 23 | - | VdWContact |
| LYS 20 | NTc.Cm11 | SER 24 | - | HBDonor |
| LYS 20 | NTc.Cm11 | SER 24 | - | VdWContact |
| VAL 21 | NTc.Cm10 | TYR 23 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | LEU 29 | - | Hydrophobic |
| LEU 32 | CX.5 | VAL 187 | - | Hydrophobic |
| LEU 32 | CX.5 | VAL 187 | - | VdWContact |
| LEU 32 | CX.5 | ALA 195 | - | Hydrophobic |
| LEU 32 | CX.5 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 32 | CX.5 | TYR 197 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.1 | ARG 278 | 6.62x62 | HBAcceptor |
| GLY 33 | cxb1.1 | ARG 278 | 6.62x62 | VdWContact |
| GLY 33 | cxb1.1 | ARG 289 | 7.28x27 | HBAcceptor |
| GLY 33 | cxb1.1 | ARG 289 | 7.28x27 | VdWContact |
| LEU 40 | cxb1.11 | PRO 38 | - | Hydrophobic |
| PRO 43 | cxb1.16 | LEU 29 | - | Hydrophobic |
| PRO 43 | cxb1.16 | LEU 29 | - | VdWContact |
| LYS 45 | B1.2 | THR 28 | - | Hydrophobic |
| LYS 45 | B1.2 | THR 28 | - | VdWContact |
| GLN 48 | B1.5 | THR 28 | - | VdWContact |
| GLN 48 | B1.5 | LEU 29 | - | HBAcceptor |
| GLN 48 | B1.5 | LEU 29 | - | HBDonor |
| GLN 48 | B1.5 | LEU 29 | - | VdWContact |
| ALA 49 | B1.6 | ALA 37 | - | Hydrophobic |
| GLU 50 | B1.7 | ALA 37 | - | VdWContact |
| GLU 50 | B1.7 | PRO 38 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 38 | - | VdWContact |
| LEU 51 | b1b2.4 | LEU 29 | - | Hydrophobic |
| LEU 51 | b1b2.4 | LEU 33 | - | Hydrophobic |
| LEU 51 | b1b2.4 | LEU 33 | - | VdWContact |
| LEU 51 | b1b2.4 | ALA 36 | - | Hydrophobic |
| CYS 52 | b1b2.6 | ALA 36 | - | HBDonor |
| CYS 52 | b1b2.6 | ALA 36 | - | VdWContact |
| TRP 59 | b1b2.14 | PHE 14 | - | Hydrophobic |
| TRP 59 | b1b2.14 | TRP 15 | - | Hydrophobic |
| GLN 62 | B2.2 | PHE 11 | - | Hydrophobic |
| GLN 62 | B2.2 | PHE 11 | - | VdWContact |
| GLN 62 | B2.2 | PHE 14 | - | VdWContact |
| LEU 63 | B2.3 | PHE 11 | - | Hydrophobic |
| HIS 66 | B2.6 | PHE 11 | - | Hydrophobic |
| HIS 66 | B2.6 | PHE 11 | - | PiStacking |
| LYS 69 | b2b3.9 | GLU 7 | - | Cationic |
| LYS 69 | b2b3.9 | GLU 7 | - | HBDonor |
| LYS 69 | b2b3.9 | GLU 7 | - | VdWContact |
| LYS 75 | B3.3 | SER 190 | - | VdWContact |
| LYS 75 | B3.3 | ASN 191 | - | HBDonor |
| LYS 75 | B3.3 | ASN 191 | - | VdWContact |
| GLN 78 | b3h.2 | TYR 188 | - | VdWContact |
