Predicted complex interactions
CCL22_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | LYS 108 | 2.64x64 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 300 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 300 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 104 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 104 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | LYS 126 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | ARG 184 | 4.64x65 | HBAcceptor |
| PRO 2 | NTc.Cm34 | ARG 184 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm34 | GLU 300 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | ILE 304 | 7.43x42 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LYS 126 | 3.32x32 | PiCation |
| TYR 3 | NTc.Cm33 | LYS 126 | 3.32x32 | VdWContact |
| TYR 3 | NTc.Cm33 | ARG 184 | 4.64x65 | VdWContact |
| TYR 3 | NTc.Cm33 | TRP 264 | 6.48x48 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TRP 264 | 6.48x48 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 267 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 267 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 300 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 300 | 7.39x38 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 300 | 7.39x38 | VdWContact |
| TYR 3 | NTc.Cm33 | ILE 304 | 7.43x42 | Hydrophobic |
| GLY 4 | NTc.Cm32 | ARG 184 | 4.64x65 | VdWContact |
| GLY 4 | NTc.Cm32 | ARG 208 | 5.35x36 | VdWContact |
| ALA 5 | NTc.Cm31 | ARG 208 | 5.35x36 | HBAcceptor |
| ALA 5 | NTc.Cm31 | ARG 208 | 5.35x36 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 296 | 7.35x34 | Hydrophobic |
| ASN 6 | NTc.Cm30 | ASP 293 | 7.32x31 | HBDonor |
| ASN 6 | NTc.Cm30 | ASP 293 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | VAL 187 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | ALA 195 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | ALA 195 | - | VdWContact |
| MET 7 | NTc.Cm29 | CYS 196 | 45.50x50 | VdWContact |
| MET 7 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| MET 7 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 208 | 5.35x36 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 278 | 6.62x62 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 278 | 6.62x62 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 278 | 6.62x62 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 289 | 7.28x27 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 289 | 7.28x27 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 289 | 7.28x27 | VdWContact |
| ASP 9 | NTc.Cm27 | PRO 41 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | PRO 41 | - | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 38 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | PRO 38 | - | VdWContact |
| CYS 12 | NTc.Cm24 | ARG 289 | 7.28x27 | Anionic |
| CYS 12 | NTc.Cm24 | ARG 289 | 7.28x27 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 39 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 39 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 284 | - | Cationic |
| ARG 14 | NTc.Cm22 | GLU 284 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 284 | - | VdWContact |
| ARG 14 | NTc.Cm22 | THR 285 | 7.24x23 | HBDonor |
| ARG 14 | NTc.Cm22 | THR 285 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 286 | 7.25x24 | Cationic |
| VAL 17 | NTc.Cm19 | LEU 33 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | LEU 33 | - | VdWContact |
| VAL 17 | NTc.Cm19 | ALA 36 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 32 | - | HBDonor |
| TYR 19 | NTc.Cm17 | PHE 32 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 32 | - | PiStacking |
| TYR 19 | NTc.Cm17 | PHE 32 | - | VdWContact |
| TYR 19 | NTc.Cm17 | LEU 33 | - | HBDonor |
| TYR 19 | NTc.Cm17 | LEU 33 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | LEU 33 | - | VdWContact |
| ARG 20 | NTc.Cm16 | PHE 14 | - | CationPi |
| ARG 20 | NTc.Cm16 | PHE 14 | - | VdWContact |
| LEU 21 | NTc.Cm15 | LEU 33 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | LEU 20 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | LEU 20 | - | VdWContact |
| SER 35 | NTc.Cm1 | TYR 197 | 45.51x51 | VdWContact |
| PRO 37 | CX.5 | ALA 205 | 5.32x33 | Hydrophobic |
| VAL 42 | cxb1.7 | PRO 38 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 25 | - | VdWContact |
| ARG 47 | cxb1.15 | SER 26 | - | HBDonor |
| ARG 47 | cxb1.15 | SER 26 | - | VdWContact |
| ARG 47 | cxb1.15 | SER 27 | - | VdWContact |
| ARG 47 | cxb1.15 | LEU 29 | - | Hydrophobic |
| LYS 49 | B1.1 | LEU 29 | - | Hydrophobic |
| LYS 49 | B1.1 | LEU 29 | - | VdWContact |
| GLU 50 | B1.2 | ALA 37 | - | VdWContact |
| GLU 50 | B1.2 | PRO 38 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 38 | - | VdWContact |
| ILE 51 | B1.3 | LEU 33 | - | Hydrophobic |
| ILE 51 | B1.3 | LEU 33 | - | VdWContact |
| ILE 51 | B1.3 | ALA 36 | - | Hydrophobic |
| CYS 52 | B1.4 | ALA 36 | - | HBDonor |
| CYS 52 | B1.4 | ALA 36 | - | VdWContact |
| MET 62 | b1b2.14 | PHE 14 | - | Hydrophobic |
