Predicted complex interactions
CCL25_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 198 | 45.52x52 | HBAcceptor |
| GLN 1 | NTc.Cm29 | GLU 198 | 45.52x52 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 198 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm29 | LEU 271 | 6.55x55 | VdWContact |
| GLN 1 | NTc.Cm29 | ASP 274 | 6.58x58 | Cationic |
| GLN 1 | NTc.Cm29 | ASP 274 | 6.58x58 | HBDonor |
| GLN 1 | NTc.Cm29 | ASP 274 | 6.58x58 | VdWContact |
| GLN 1 | NTc.Cm29 | ARG 278 | 6.62x62 | VdWContact |
| GLN 1 | NTc.Cm29 | LEU 296 | 7.35x34 | VdWContact |
| GLY 2 | NTc.Cm28 | TYR 197 | 45.51x51 | VdWContact |
| GLY 2 | NTc.Cm28 | ASP 293 | 7.32x31 | VdWContact |
| VAL 3 | NTc.Cm27 | PRO 41 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | ARG 289 | 7.28x27 | Hydrophobic |
| VAL 3 | NTc.Cm27 | ARG 289 | 7.28x27 | VdWContact |
| VAL 3 | NTc.Cm27 | ASP 293 | 7.32x31 | HBDonor |
| VAL 3 | NTc.Cm27 | ASP 293 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 187 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 187 | - | VdWContact |
| PHE 4 | NTc.Cm26 | SER 189 | - | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 192 | - | VdWContact |
| PHE 4 | NTc.Cm26 | ALA 195 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | TYR 197 | 45.51x51 | Hydrophobic |
| ASP 6 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | CYS 39 | - | VdWContact |
| CYS 7 | NTc.Cm23 | PRO 38 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 39 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 39 | - | VdWContact |
| CYS 7 | NTc.Cm23 | ARG 289 | 7.28x27 | Anionic |
| CYS 7 | NTc.Cm23 | ARG 289 | 7.28x27 | VdWContact |
| CYS 8 | NTc.Cm22 | PRO 38 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 39 | - | VdWContact |
| LEU 9 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLU 284 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ARG 289 | 7.28x27 | VdWContact |
| ALA 10 | NTc.Cm20 | ALA 36 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | LEU 33 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | LEU 33 | - | VdWContact |
| HIS 12 | NTc.Cm18 | ALA 36 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ALA 36 | - | VdWContact |
| ARG 27 | NTc.Cm3 | SER 189 | - | HBDonor |
| ARG 27 | NTc.Cm3 | SER 189 | - | VdWContact |
| ARG 27 | NTc.Cm3 | SER 190 | - | VdWContact |
| VAL 31 | CX.5 | ASN 202 | - | HBDonor |
| VAL 31 | CX.5 | ASN 202 | - | Hydrophobic |
| VAL 31 | CX.5 | ASN 202 | - | VdWContact |
| GLY 33 | cxb1.2 | TYR 197 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.2 | GLU 198 | 45.52x52 | VdWContact |
| GLY 33 | cxb1.2 | ARG 208 | 5.35x36 | VdWContact |
| SER 34 | cxb1.5 | ARG 278 | 6.62x62 | VdWContact |
| SER 34 | cxb1.5 | ARG 289 | 7.28x27 | HBAcceptor |
| SER 34 | cxb1.5 | ARG 289 | 7.28x27 | VdWContact |
| ASN 36 | cxb1.8 | ARG 278 | 6.62x62 | VdWContact |
| ASN 36 | cxb1.8 | GLU 284 | - | HBDonor |
| ASN 36 | cxb1.8 | GLU 284 | - | VdWContact |
| ILE 41 | cxb1.16 | PRO 38 | - | Hydrophobic |
| LYS 46 | B1.5 | LEU 20 | - | HBDonor |
| LYS 46 | B1.5 | LEU 20 | - | VdWContact |
| LYS 46 | B1.5 | TYR 25 | - | Hydrophobic |
| ARG 49 | b1b2.1 | LEU 29 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 38 | - | Hydrophobic |
| LYS 50 | b1b2.2 | GLU 40 | - | Cationic |
| LYS 50 | b1b2.2 | GLU 40 | - | VdWContact |
| CYS 52 | b1b2.4 | ALA 36 | - | VdWContact |
| CYS 52 | b1b2.4 | PRO 38 | - | VdWContact |
| VAL 73 | B3.1 | PHE 11 | - | Hydrophobic |
