Predicted complex interactions
CCL27_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 76
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | TRP 104 | 2.60x60 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TRP 104 | 2.60x60 | VdWContact |
| PHE 1 | NTc.Cm32 | SER 123 | 3.29x29 | VdWContact |
| PHE 1 | NTc.Cm32 | LYS 126 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm32 | LYS 126 | 3.32x32 | PiCation |
| PHE 1 | NTc.Cm32 | LYS 126 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 127 | 3.33x33 | Hydrophobic |
| PHE 1 | NTc.Cm32 | GLU 127 | 3.33x33 | VdWContact |
| PHE 1 | NTc.Cm32 | VAL 180 | 4.60x61 | Hydrophobic |
| PHE 1 | NTc.Cm32 | ARG 184 | 4.64x65 | PiCation |
| PHE 1 | NTc.Cm32 | ARG 184 | 4.64x65 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 267 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 300 | 7.39x38 | Cationic |
| LEU 2 | NTc.Cm31 | TRP 104 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 104 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 197 | 45.51x51 | VdWContact |
| LEU 3 | NTc.Cm30 | TYR 197 | 45.51x51 | VdWContact |
| LEU 3 | NTc.Cm30 | ARG 278 | 6.62x62 | VdWContact |
| LEU 3 | NTc.Cm30 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm30 | LEU 296 | 7.35x34 | VdWContact |
| PRO 4 | NTc.Cm29 | ALA 195 | - | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| PRO 5 | NTc.Cm28 | VAL 192 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | VAL 192 | - | VdWContact |
| PRO 5 | NTc.Cm28 | ALA 195 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | ALA 195 | - | VdWContact |
| SER 6 | NTc.Cm27 | PRO 41 | - | VdWContact |
| ALA 8 | NTc.Cm25 | PRO 38 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 39 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 39 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 39 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 39 | - | VdWContact |
| CYS 9 | NTc.Cm24 | ARG 289 | 7.28x27 | Anionic |
| CYS 9 | NTc.Cm24 | ARG 289 | 7.28x27 | VdWContact |
| THR 11 | NTc.Cm22 | CYS 39 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | CYS 39 | - | VdWContact |
| THR 11 | NTc.Cm22 | GLU 284 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | GLU 284 | - | VdWContact |
| GLN 12 | NTc.Cm21 | ASP 35 | - | VdWContact |
| TYR 14 | NTc.Cm19 | PHE 32 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 32 | - | VdWContact |
| TYR 14 | NTc.Cm19 | LEU 33 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | LEU 33 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ALA 36 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | ALA 36 | - | VdWContact |
| LEU 18 | NTc.Cm15 | LEU 33 | - | Hydrophobic |
| ASP 35 | cxb1.1 | GLY 201 | - | VdWContact |
| ASP 35 | cxb1.1 | ASN 203 | 5.30x31 | HBAcceptor |
| ASP 35 | cxb1.1 | ASN 203 | 5.30x31 | VdWContact |
| ASP 35 | cxb1.1 | THR 204 | 5.31x32 | HBAcceptor |
| ASP 35 | cxb1.1 | THR 204 | 5.31x32 | VdWContact |
| ASP 35 | cxb1.1 | ALA 205 | 5.32x33 | HBAcceptor |
| ASP 35 | cxb1.1 | ALA 205 | 5.32x33 | VdWContact |
| GLY 36 | cxb1.2 | ARG 208 | 5.35x36 | VdWContact |
| GLY 36 | cxb1.2 | ARG 278 | 6.62x62 | HBAcceptor |
| GLY 36 | cxb1.2 | ARG 278 | 6.62x62 | VdWContact |
| ASP 37 | cxb1.5 | TYR 197 | 45.51x51 | HBAcceptor |
| ASP 37 | cxb1.5 | TYR 197 | 45.51x51 | VdWContact |
| ASP 37 | cxb1.5 | ARG 208 | 5.35x36 | Anionic |
| ASP 37 | cxb1.5 | ARG 278 | 6.62x62 | Anionic |
| ASP 37 | cxb1.5 | ARG 289 | 7.28x27 | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 289 | 7.28x27 | VdWContact |
| HIS 39 | cxb1.7 | ARG 278 | 6.62x62 | Hydrophobic |
| HIS 39 | cxb1.7 | ARG 278 | 6.62x62 | VdWContact |
| HIS 39 | cxb1.7 | GLU 284 | - | VdWContact |
| VAL 44 | cxb1.15 | PRO 38 | - | Hydrophobic |
| ARG 50 | B1.2 | LEU 29 | - | VdWContact |
| SER 51 | B1.3 | ALA 37 | - | VdWContact |
| ILE 52 | B1.4 | LEU 33 | - | Hydrophobic |
| ILE 52 | B1.4 | LEU 33 | - | VdWContact |
| ILE 52 | B1.4 | ALA 36 | - | Hydrophobic |
| ILE 52 | B1.4 | ALA 36 | - | VdWContact |
| CYS 53 | B1.5 | ALA 36 | - | HBDonor |
| CYS 53 | B1.5 | ALA 36 | - | VdWContact |
| CYS 53 | B1.5 | PRO 38 | - | VdWContact |
