Predicted complex interactions
CCL28_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 115
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm29 | GLU 127 | 3.33x33 | Cationic |
| SER 1 | NTc.Cm29 | ARG 184 | 4.64x65 | VdWContact |
| SER 1 | NTc.Cm29 | TYR 267 | 6.51x51 | HBDonor |
| SER 1 | NTc.Cm29 | TYR 267 | 6.51x51 | VdWContact |
| GLU 2 | NTc.Cm28 | TRP 104 | 2.60x60 | Hydrophobic |
| GLU 2 | NTc.Cm28 | TRP 104 | 2.60x60 | VdWContact |
| GLU 2 | NTc.Cm28 | LYS 108 | 2.64x64 | Anionic |
| GLU 2 | NTc.Cm28 | ARG 184 | 4.64x65 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 197 | 45.51x51 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TYR 197 | 45.51x51 | VdWContact |
| ILE 4 | NTc.Cm26 | ARG 212 | 5.39x40 | VdWContact |
| ILE 4 | NTc.Cm26 | ASP 274 | 6.58x58 | Hydrophobic |
| ILE 4 | NTc.Cm26 | ASP 274 | 6.58x58 | VdWContact |
| ILE 4 | NTc.Cm26 | ARG 278 | 6.62x62 | VdWContact |
| ILE 4 | NTc.Cm26 | ARG 289 | 7.28x27 | VdWContact |
| ILE 4 | NTc.Cm26 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 197 | 45.51x51 | VdWContact |
| PRO 6 | NTc.Cm24 | VAL 192 | - | Hydrophobic |
| PRO 6 | NTc.Cm24 | ALA 195 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | VAL 187 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | VAL 187 | - | VdWContact |
| ILE 7 | NTc.Cm23 | SER 189 | - | VdWContact |
| ALA 8 | NTc.Cm22 | ARG 289 | 7.28x27 | VdWContact |
| SER 9 | NTc.Cm21 | CYS 39 | - | VdWContact |
| SER 9 | NTc.Cm21 | PRO 41 | - | VdWContact |
| SER 10 | NTc.Cm20 | PRO 38 | - | VdWContact |
| CYS 11 | NTc.Cm19 | PRO 38 | - | VdWContact |
| CYS 11 | NTc.Cm19 | CYS 39 | - | HBAcceptor |
| CYS 11 | NTc.Cm19 | CYS 39 | - | VdWContact |
| CYS 12 | NTc.Cm18 | PRO 38 | - | VdWContact |
| THR 13 | NTc.Cm17 | CYS 39 | - | VdWContact |
| THR 13 | NTc.Cm17 | GLU 284 | - | Hydrophobic |
| GLU 14 | NTc.Cm16 | ASP 35 | - | VdWContact |
| SER 16 | NTc.Cm14 | ALA 36 | - | VdWContact |
| HIS 18 | NTc.Cm12 | PRO 30 | - | Hydrophobic |
| HIS 18 | NTc.Cm12 | PRO 30 | - | VdWContact |
| ILE 19 | NTc.Cm11 | PHE 32 | - | Hydrophobic |
| SER 20 | NTc.Cm10 | LEU 29 | - | VdWContact |
| ARG 21 | NTc.Cm9 | TYR 25 | - | CationPi |
| ARG 21 | NTc.Cm9 | TYR 25 | - | Hydrophobic |
| ARG 21 | NTc.Cm9 | TYR 25 | - | VdWContact |
| LEU 23 | NTc.Cm7 | PHE 32 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | PHE 32 | - | VdWContact |
| CYS 30 | CX.1 | PHE 11 | - | VdWContact |
| ARG 31 | CX.5 | SER 190 | - | HBDonor |
| ARG 31 | CX.5 | SER 190 | - | VdWContact |
| ILE 32 | cxb1.1 | MET 6 | - | Hydrophobic |
| ILE 32 | cxb1.1 | PHE 11 | - | Hydrophobic |
| ILE 32 | cxb1.1 | PHE 11 | - | VdWContact |
| ILE 32 | cxb1.1 | PHE 14 | - | Hydrophobic |
| ARG 34 | cxb1.5 | SER 10 | - | HBDonor |
| ARG 34 | cxb1.5 | SER 10 | - | VdWContact |
| ASP 36 | cxb1.7 | ASN 202 | - | VdWContact |
| ASP 36 | cxb1.7 | THR 204 | 5.31x32 | HBAcceptor |
| ASP 36 | cxb1.7 | THR 204 | 5.31x32 | VdWContact |
| ASP 36 | cxb1.7 | ALA 205 | 5.32x33 | HBAcceptor |
| ASP 36 | cxb1.7 | ALA 205 | 5.32x33 | VdWContact |
| GLY 37 | cxb1.8 | ALA 205 | 5.32x33 | VdWContact |
| GLY 37 | cxb1.8 | ARG 208 | 5.35x36 | HBAcceptor |
| GLY 37 | cxb1.8 | ARG 208 | 5.35x36 | VdWContact |
| GLY 37 | cxb1.8 | ARG 278 | 6.62x62 | VdWContact |
| ASP 38 | cxb1.10 | ARG 208 | 5.35x36 | Anionic |
| ASP 38 | cxb1.10 | ARG 208 | 5.35x36 | HBAcceptor |
| ASP 38 | cxb1.10 | ARG 208 | 5.35x36 | VdWContact |
| ASP 40 | cxb1.12 | ARG 278 | 6.62x62 | Anionic |
| ASP 40 | cxb1.12 | ARG 278 | 6.62x62 | VdWContact |
| ALA 42 | cxb1.14 | PHE 14 | - | Hydrophobic |
| ILE 45 | B1.1 | PRO 38 | - | Hydrophobic |
| ILE 45 | B1.1 | PRO 38 | - | VdWContact |
| ARG 52 | b1b2.4 | PRO 38 | - | Hydrophobic |
| ARG 52 | b1b2.4 | GLU 40 | - | Cationic |
| ARG 52 | b1b2.4 | GLU 40 | - | HBDonor |
| ARG 52 | b1b2.4 | GLU 40 | - | VdWContact |
| ILE 53 | b1b2.6 | PHE 32 | - | Hydrophobic |
| ILE 53 | b1b2.6 | ALA 36 | - | VdWContact |
| CYS 54 | b1b2.7 | ALA 36 | - | HBDonor |
| CYS 54 | b1b2.7 | ALA 36 | - | Hydrophobic |
| CYS 54 | b1b2.7 | ALA 36 | - | VdWContact |
| CYS 54 | b1b2.7 | ALA 37 | - | VdWContact |
| CYS 54 | b1b2.7 | PRO 38 | - | VdWContact |
| PRO 57 | b1b2.10 | PHE 14 | - | Hydrophobic |
| PRO 57 | b1b2.10 | PHE 14 | - | VdWContact |
| PRO 57 | b1b2.10 | TRP 15 | - | Hydrophobic |
| PRO 57 | b1b2.10 | TRP 15 | - | VdWContact |
| HIS 58 | b1b2.12 | TRP 15 | - | Hydrophobic |
| HIS 58 | b1b2.12 | TRP 15 | - | VdWContact |
| HIS 60 | b1b2.14 | LEU 20 | - | Hydrophobic |
| HIS 60 | b1b2.14 | LEU 20 | - | VdWContact |
| HIS 60 | b1b2.14 | TYR 23 | - | Hydrophobic |
| HIS 60 | b1b2.14 | TYR 23 | - | PiStacking |
| HIS 60 | b1b2.14 | TYR 23 | - | VdWContact |
| THR 61 | b1b2.16 | TYR 25 | - | Hydrophobic |
| LYS 63 | B2.2 | TRP 15 | - | Hydrophobic |
| LYS 63 | B2.2 | TRP 15 | - | VdWContact |
| LYS 63 | B2.2 | GLU 18 | - | Cationic |
| LYS 63 | B2.2 | GLU 18 | - | HBDonor |
| LYS 63 | B2.2 | GLU 18 | - | VdWContact |
| LYS 63 | B2.2 | LEU 20 | - | Hydrophobic |
| LYS 63 | B2.2 | LEU 20 | - | VdWContact |
| GLN 64 | B2.3 | LEU 20 | - | HBDonor |
| GLN 64 | B2.3 | LEU 20 | - | Hydrophobic |
| GLN 64 | B2.3 | LEU 20 | - | VdWContact |
| GLN 64 | B2.3 | TYR 25 | - | HBAcceptor |
| GLN 64 | B2.3 | TYR 25 | - | VdWContact |
| MET 66 | B2.5 | PHE 11 | - | Hydrophobic |
| MET 66 | B2.5 | PHE 11 | - | VdWContact |
| MET 66 | B2.5 | TRP 15 | - | Hydrophobic |
| MET 66 | B2.5 | TRP 15 | - | VdWContact |
| LYS 67 | B2.6 | LEU 20 | - | Hydrophobic |
| LYS 67 | B2.6 | LEU 20 | - | VdWContact |
| LYS 73 | B3.3 | SER 8 | - | HBDonor |
| LYS 73 | B3.3 | SER 8 | - | VdWContact |
| CYS 80 | H.2 | PHE 11 | - | Hydrophobic |
| ARG 82 | H.4 | ASP 3 | - | Cationic |
