Predicted complex interactions
CCL7_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 75
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | LYS 126 | 3.32x32 | HBAcceptor |
| GLN 1 | NTc.Cm33 | LYS 126 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 127 | 3.33x33 | Cationic |
| GLN 1 | NTc.Cm33 | GLU 127 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm33 | ARG 184 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 267 | 6.51x51 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 267 | 6.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 300 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 267 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 271 | 6.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm32 | LEU 271 | 6.55x55 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 296 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm31 | TRP 104 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm31 | TYR 197 | 45.51x51 | VdWContact |
| ILE 5 | NTc.Cm29 | ALA 195 | - | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 197 | 45.51x51 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| ASN 6 | NTc.Cm28 | LEU 44 | - | VdWContact |
| THR 7 | NTc.Cm27 | PRO 41 | - | VdWContact |
| THR 7 | NTc.Cm27 | VAL 192 | - | VdWContact |
| SER 8 | NTc.Cm26 | PRO 41 | - | VdWContact |
| SER 8 | NTc.Cm26 | VAL 192 | - | VdWContact |
| THR 9 | NTc.Cm25 | SER 189 | - | HBDonor |
| THR 9 | NTc.Cm25 | SER 189 | - | VdWContact |
| THR 10 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 38 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 39 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 39 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 39 | - | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 39 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 39 | - | VdWContact |
| TYR 13 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | GLU 284 | - | VdWContact |
| TYR 13 | NTc.Cm21 | ARG 289 | 7.28x27 | Hydrophobic |
| TYR 13 | NTc.Cm21 | ARG 289 | 7.28x27 | VdWContact |
| ARG 14 | NTc.Cm20 | ASP 35 | - | Cationic |
| ARG 14 | NTc.Cm20 | ASP 35 | - | HBDonor |
| ARG 14 | NTc.Cm20 | ASP 35 | - | VdWContact |
| ARG 14 | NTc.Cm20 | GLN 283 | - | VdWContact |
| ARG 14 | NTc.Cm20 | GLU 284 | - | HBDonor |
| ARG 14 | NTc.Cm20 | GLU 284 | - | VdWContact |
| ARG 14 | NTc.Cm20 | THR 285 | 7.24x23 | VdWContact |
| ILE 16 | NTc.Cm18 | PHE 32 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | LEU 33 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | LEU 33 | - | VdWContact |
| ILE 16 | NTc.Cm18 | ALA 36 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | PHE 14 | - | VdWContact |
| LYS 18 | NTc.Cm16 | TRP 15 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | TRP 15 | - | VdWContact |
| LYS 18 | NTc.Cm16 | GLU 18 | - | Cationic |
| LYS 19 | NTc.Cm15 | TRP 15 | - | VdWContact |
| PRO 21 | NTc.Cm13 | TRP 15 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TRP 15 | - | VdWContact |
| ARG 24 | NTc.Cm10 | LEU 20 | - | HBDonor |
| ARG 24 | NTc.Cm10 | LEU 20 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 23 | - | CationPi |
| ARG 24 | NTc.Cm10 | TYR 23 | - | VdWContact |
| SER 33 | NTc.Cm1 | ASN 202 | - | HBDonor |
| SER 33 | NTc.Cm1 | ASN 202 | - | VdWContact |
| HIS 35 | CX.5 | VAL 187 | - | Hydrophobic |
| HIS 35 | CX.5 | VAL 187 | - | VdWContact |
| PRO 37 | cxb1.2 | ARG 278 | 6.62x62 | Hydrophobic |
| PRO 37 | cxb1.2 | ARG 278 | 6.62x62 | VdWContact |
| ILE 42 | cxb1.10 | PRO 38 | - | Hydrophobic |
| LYS 49 | B1.3 | SER 27 | - | HBDonor |
| LYS 49 | B1.3 | LEU 29 | - | Hydrophobic |
| LYS 49 | B1.3 | LEU 29 | - | VdWContact |
| GLU 50 | B1.4 | PRO 38 | - | Hydrophobic |
| GLU 50 | B1.4 | PRO 38 | - | VdWContact |
| ILE 51 | B1.5 | LEU 33 | - | Hydrophobic |
| ILE 51 | B1.5 | ALA 36 | - | Hydrophobic |
| CYS 52 | B1.6 | ALA 36 | - | HBDonor |
| CYS 52 | B1.6 | ALA 36 | - | VdWContact |
| CYS 52 | B1.6 | PRO 38 | - | VdWContact |
