Predicted complex interactions
CCL8_HUMAN + CXCR2
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 78
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | GLU 127 | 3.33x33 | HBDonor |
| GLN 1 | NTc.Cm33 | GLU 127 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm33 | ARG 184 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 267 | 6.51x51 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 267 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | ASP 297 | 7.36x35 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 300 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 300 | 7.39x38 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 184 | 4.64x65 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 184 | 4.64x65 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 184 | 4.64x65 | VdWContact |
| ASP 3 | NTc.Cm31 | CYS 196 | 45.50x50 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 197 | 45.51x51 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 197 | 45.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 208 | 5.35x36 | Anionic |
| SER 4 | NTc.Cm30 | LYS 108 | 2.64x64 | HBAcceptor |
| SER 4 | NTc.Cm30 | LYS 108 | 2.64x64 | VdWContact |
| SER 4 | NTc.Cm30 | ASP 297 | 7.36x35 | VdWContact |
| VAL 5 | NTc.Cm29 | VAL 192 | - | Hydrophobic |
| VAL 5 | NTc.Cm29 | VAL 192 | - | VdWContact |
| VAL 5 | NTc.Cm29 | ALA 195 | - | Hydrophobic |
| VAL 5 | NTc.Cm29 | ALA 195 | - | VdWContact |
| SER 6 | NTc.Cm28 | LYS 48 | 1.32x32 | HBAcceptor |
| SER 6 | NTc.Cm28 | LYS 48 | 1.32x32 | VdWContact |
| SER 6 | NTc.Cm28 | SER 193 | - | HBDonor |
| SER 6 | NTc.Cm28 | SER 193 | - | VdWContact |
| ILE 7 | NTc.Cm27 | VAL 192 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | VAL 192 | - | VdWContact |
| ILE 7 | NTc.Cm27 | SER 193 | - | VdWContact |
| PRO 8 | NTc.Cm26 | PRO 41 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | PRO 41 | - | VdWContact |
| ILE 9 | NTc.Cm25 | PRO 41 | - | VdWContact |
| ILE 9 | NTc.Cm25 | VAL 192 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 38 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | CYS 39 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLU 40 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | GLU 40 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 39 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 39 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 39 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 39 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 39 | - | VdWContact |
| PHE 13 | NTc.Cm21 | GLU 284 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 284 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ARG 289 | 7.28x27 | PiCation |
| PHE 13 | NTc.Cm21 | ARG 289 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ASP 35 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASP 35 | - | VdWContact |
| ILE 16 | NTc.Cm18 | PHE 32 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | PHE 32 | - | VdWContact |
| ILE 16 | NTc.Cm18 | LEU 33 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | ALA 36 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | GLU 18 | - | Cationic |
| ARG 24 | NTc.Cm10 | LEU 20 | - | VdWContact |
| ASN 33 | NTc.Cm1 | SER 189 | - | VdWContact |
| ILE 34 | CX.1 | VAL 187 | - | Hydrophobic |
| ILE 34 | CX.1 | VAL 187 | - | VdWContact |
| ILE 34 | CX.1 | TYR 197 | 45.51x51 | Hydrophobic |
| ILE 34 | CX.1 | ASP 199 | - | Hydrophobic |
| ILE 34 | CX.1 | ASP 199 | - | VdWContact |
| ILE 34 | CX.1 | THR 204 | 5.31x32 | Hydrophobic |
| ILE 34 | CX.1 | THR 204 | 5.31x32 | VdWContact |
| GLN 35 | CX.5 | TYR 197 | 45.51x51 | Hydrophobic |
| GLN 35 | CX.5 | TYR 197 | 45.51x51 | VdWContact |
| PRO 37 | cxb1.2 | ALA 205 | 5.32x33 | Hydrophobic |
| PRO 37 | cxb1.2 | ALA 205 | 5.32x33 | VdWContact |
| ILE 42 | cxb1.10 | PRO 38 | - | Hydrophobic |
| LYS 49 | B1.3 | SER 27 | - | HBDonor |
| LYS 49 | B1.3 | SER 27 | - | VdWContact |
| LYS 49 | B1.3 | LEU 29 | - | Hydrophobic |
| LYS 49 | B1.3 | LEU 29 | - | VdWContact |
| GLU 50 | B1.4 | PRO 38 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 33 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 33 | - | VdWContact |
| VAL 51 | B1.5 | ALA 36 | - | Hydrophobic |
| CYS 52 | B1.6 | ALA 36 | - | HBDonor |
| CYS 52 | B1.6 | ALA 36 | - | VdWContact |
| CYS 52 | B1.6 | PRO 38 | - | VdWContact |
