Predicted complex interactions
CXCL1_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 137
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | SER 193 | - | VdWContact |
| SER 2 | NTc.Cm41 | VAL 192 | - | VdWContact |
| VAL 3 | NTc.Cm40 | SER 107 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm40 | LYS 108 | 2.64x64 | VdWContact |
| VAL 3 | NTc.Cm40 | SER 193 | - | VdWContact |
| THR 5 | NTc.Cm38 | LYS 108 | 2.64x64 | VdWContact |
| THR 5 | NTc.Cm38 | TYR 197 | 45.51x51 | VdWContact |
| THR 5 | NTc.Cm38 | ASP 297 | 7.36x35 | HBDonor |
| THR 5 | NTc.Cm38 | ASP 297 | 7.36x35 | VdWContact |
| GLU 6 | NTc.Cm37 | TYR 197 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 208 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 208 | 5.35x36 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 212 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 212 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 278 | 6.62x62 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 278 | 6.62x62 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 278 | 6.62x62 | VdWContact |
| GLU 6 | NTc.Cm37 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 7 | NTc.Cm36 | VAL 187 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | TYR 197 | 45.51x51 | HBDonor |
| LEU 7 | NTc.Cm36 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 7 | NTc.Cm36 | TYR 197 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 278 | 6.62x62 | HBAcceptor |
| LEU 7 | NTc.Cm36 | ARG 278 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 274 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 274 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 274 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | MET 277 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | GLU 284 | - | Cationic |
| ARG 8 | NTc.Cm35 | ASP 293 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 293 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 293 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm34 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 9 | NTc.Cm34 | ARG 289 | 7.28x27 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 38 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | CYS 39 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 39 | - | VdWContact |
| LEU 12 | NTc.Cm31 | GLU 284 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | GLU 284 | - | VdWContact |
| LEU 12 | NTc.Cm31 | ARG 289 | 7.28x27 | VdWContact |
| GLN 13 | NTc.Cm30 | ASP 35 | - | VdWContact |
| LEU 15 | NTc.Cm28 | PRO 30 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | LEU 33 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | LEU 33 | - | VdWContact |
| LEU 15 | NTc.Cm28 | ALA 36 | - | Hydrophobic |
| GLY 17 | NTc.Cm26 | SER 26 | - | HBAcceptor |
| GLY 17 | NTc.Cm26 | SER 26 | - | VdWContact |
| HIS 19 | NTc.Cm24 | LEU 20 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | TYR 25 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | TYR 25 | - | VdWContact |
| HIS 19 | NTc.Cm24 | SER 26 | - | HBDonor |
| HIS 19 | NTc.Cm24 | SER 26 | - | VdWContact |
| HIS 19 | NTc.Cm24 | SER 27 | - | VdWContact |
| PRO 20 | NTc.Cm23 | PHE 11 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | PHE 11 | - | VdWContact |
| PRO 20 | NTc.Cm23 | TRP 15 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | TRP 15 | - | VdWContact |
| PRO 20 | NTc.Cm23 | LEU 20 | - | Hydrophobic |
| LYS 21 | NTc.Cm22 | GLU 12 | - | Hydrophobic |
| LYS 21 | NTc.Cm22 | GLU 12 | - | VdWContact |
| ASN 22 | NTc.Cm21 | SER 27 | - | HBDonor |
| ASN 22 | NTc.Cm21 | SER 27 | - | VdWContact |
| ASN 22 | NTc.Cm21 | LEU 29 | - | Hydrophobic |
| ILE 23 | NTc.Cm20 | PHE 11 | - | Hydrophobic |
| SER 25 | NTc.Cm18 | MET 6 | - | VdWContact |
| VAL 26 | NTc.Cm17 | ASN 5 | - | VdWContact |
| VAL 26 | NTc.Cm17 | MET 6 | - | HBAcceptor |
| VAL 26 | NTc.Cm17 | MET 6 | - | HBDonor |
| VAL 26 | NTc.Cm17 | MET 6 | - | VdWContact |
| VAL 26 | NTc.Cm17 | PHE 11 | - | Hydrophobic |
| ASN 27 | NTc.Cm16 | PHE 4 | - | VdWContact |
| VAL 28 | NTc.Cm15 | ASP 3 | - | VdWContact |
| VAL 28 | NTc.Cm15 | PHE 4 | - | HBAcceptor |
| VAL 28 | NTc.Cm15 | PHE 4 | - | HBDonor |
| VAL 28 | NTc.Cm15 | PHE 4 | - | VdWContact |
| LYS 29 | NTc.Cm14 | ASP 3 | - | VdWContact |
| LYS 29 | NTc.Cm14 | SER 190 | - | VdWContact |
| SER 30 | NTc.Cm13 | MET 1 | - | VdWContact |
| SER 30 | NTc.Cm13 | ASP 3 | - | HBDonor |
| SER 30 | NTc.Cm13 | ASP 3 | - | VdWContact |
| PRO 31 | NTc.Cm12 | ASN 202 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | VAL 187 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | ASP 199 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | ASP 199 | - | VdWContact |
| PRO 33 | NTc.Cm10 | THR 204 | 5.31x32 | Hydrophobic |
| ALA 36 | NTc.Cm7 | ASN 202 | - | VdWContact |
| ILE 41 | NTc.Cm2 | PRO 38 | - | Hydrophobic |
| LEU 44 | CX.4 | LEU 29 | - | Hydrophobic |
| LEU 44 | CX.4 | LEU 33 | - | Hydrophobic |
| LYS 45 | CX.5 | GLU 12 | - | Cationic |
| LYS 45 | CX.5 | GLU 12 | - | HBDonor |
| LYS 45 | CX.5 | GLU 12 | - | VdWContact |
| ASN 46 | cxb1.1 | LEU 29 | - | VdWContact |
| ARG 48 | cxb1.5 | PRO 31 | - | HBDonor |
| ARG 48 | cxb1.5 | PRO 31 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 38 | - | Hydrophobic |
| LYS 49 | cxb1.6 | GLU 40 | - | Cationic |
| LYS 49 | cxb1.6 | GLU 40 | - | HBDonor |
| LYS 49 | cxb1.6 | GLU 40 | - | VdWContact |
| ALA 50 | cxb1.8 | LEU 33 | - | Hydrophobic |
| CYS 51 | cxb1.10 | ALA 36 | - | HBDonor |
| CYS 51 | cxb1.10 | ALA 36 | - | VdWContact |
| PRO 57 | B1.2 | TYR 23 | - | Hydrophobic |
| PRO 57 | B1.2 | TYR 23 | - | VdWContact |
| ILE 58 | B1.3 | LEU 20 | - | Hydrophobic |
| ILE 58 | B1.3 | TYR 23 | - | Hydrophobic |
| ILE 58 | B1.3 | TYR 23 | - | VdWContact |
| ILE 58 | B1.3 | TYR 25 | - | Hydrophobic |
| LYS 61 | B1.6 | TRP 15 | - | Hydrophobic |
| LYS 61 | B1.6 | TRP 15 | - | VdWContact |
| LYS 61 | B1.6 | GLU 18 | - | Cationic |
| LYS 61 | B1.6 | GLU 18 | - | HBDonor |
| LYS 61 | B1.6 | GLU 18 | - | VdWContact |
| LYS 61 | B1.6 | TYR 23 | - | HBDonor |
| LYS 61 | B1.6 | TYR 23 | - | Hydrophobic |
| LYS 61 | B1.6 | TYR 23 | - | VdWContact |
| ILE 62 | B1.7 | PHE 11 | - | Hydrophobic |
| ILE 62 | B1.7 | TRP 15 | - | Hydrophobic |
| ILE 62 | B1.7 | TRP 15 | - | VdWContact |
| ILE 63 | b1b2.4 | MET 1 | - | Hydrophobic |
| LYS 65 | b1b2.7 | PHE 14 | - | HBDonor |
| LYS 65 | b1b2.7 | PHE 14 | - | Hydrophobic |
| LYS 65 | b1b2.7 | PHE 14 | - | VdWContact |
| LYS 65 | b1b2.7 | TRP 15 | - | Hydrophobic |
| LYS 65 | b1b2.7 | GLU 18 | - | Cationic |
| LYS 65 | b1b2.7 | GLU 18 | - | HBDonor |
| LYS 65 | b1b2.7 | GLU 18 | - | VdWContact |
| MET 66 | b1b2.8 | MET 6 | - | Hydrophobic |
| MET 66 | b1b2.8 | MET 6 | - | VdWContact |
| MET 66 | b1b2.8 | PHE 11 | - | Hydrophobic |
| MET 66 | b1b2.8 | PHE 11 | - | VdWContact |
| LEU 67 | b1b2.9 | MET 1 | - | Hydrophobic |
| LEU 67 | b1b2.9 | MET 1 | - | VdWContact |
| SER 69 | b1b2.12 | PHE 14 | - | VdWContact |
| ASP 70 | b1b2.13 | PHE 4 | - | Hydrophobic |
| ASP 70 | b1b2.13 | PHE 4 | - | VdWContact |
