Predicted complex interactions
CXCL11_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL11_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 151
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm29 | LYS 126 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm29 | PHE 130 | 3.36x36 | VdWContact |
| PHE 1 | NTc.Cm29 | TRP 264 | 6.48x48 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TRP 264 | 6.48x48 | VdWContact |
| PHE 1 | NTc.Cm29 | TYR 267 | 6.51x51 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TYR 267 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm29 | GLU 300 | 7.39x38 | Hydrophobic |
| PHE 1 | NTc.Cm29 | GLU 300 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 127 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm28 | PRO 215 | 5.42x43 | Hydrophobic |
| PRO 2 | NTc.Cm28 | PRO 215 | 5.42x43 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 267 | 6.51x51 | HBAcceptor |
| PRO 2 | NTc.Cm28 | TYR 267 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 267 | 6.51x51 | VdWContact |
| MET 3 | NTc.Cm27 | TRP 104 | 2.60x60 | Hydrophobic |
| MET 3 | NTc.Cm27 | TRP 104 | 2.60x60 | VdWContact |
| MET 3 | NTc.Cm27 | LYS 126 | 3.32x32 | Hydrophobic |
| MET 3 | NTc.Cm27 | LYS 126 | 3.32x32 | VdWContact |
| MET 3 | NTc.Cm27 | GLU 127 | 3.33x33 | HBDonor |
| MET 3 | NTc.Cm27 | GLU 127 | 3.33x33 | VdWContact |
| MET 3 | NTc.Cm27 | ARG 184 | 4.64x65 | VdWContact |
| MET 3 | NTc.Cm27 | GLU 198 | 45.52x52 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 180 | 4.60x61 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 198 | 45.52x52 | HBDonor |
| PHE 4 | NTc.Cm26 | GLU 198 | 45.52x52 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 198 | 45.52x52 | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 208 | 5.35x36 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ARG 208 | 5.35x36 | VdWContact |
| PHE 4 | NTc.Cm26 | LEU 211 | 5.38x39 | Hydrophobic |
| PHE 4 | NTc.Cm26 | LEU 211 | 5.38x39 | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 212 | 5.39x40 | HBAcceptor |
| PHE 4 | NTc.Cm26 | ARG 212 | 5.39x40 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ARG 212 | 5.39x40 | VdWContact |
| LYS 5 | NTc.Cm25 | ARG 278 | 6.62x62 | VdWContact |
| LYS 5 | NTc.Cm25 | LEU 296 | 7.35x34 | Hydrophobic |
| LYS 5 | NTc.Cm25 | ASP 297 | 7.36x35 | Cationic |
| LYS 5 | NTc.Cm25 | ASP 297 | 7.36x35 | HBDonor |
| LYS 5 | NTc.Cm25 | ASP 297 | 7.36x35 | VdWContact |
| LYS 5 | NTc.Cm25 | GLU 300 | 7.39x38 | Cationic |
| LYS 5 | NTc.Cm25 | GLU 300 | 7.39x38 | HBDonor |
| LYS 5 | NTc.Cm25 | GLU 300 | 7.39x38 | VdWContact |
| ARG 6 | NTc.Cm24 | GLU 45 | 1.29x29 | Cationic |
| ARG 6 | NTc.Cm24 | GLU 45 | 1.29x29 | HBDonor |
| ARG 6 | NTc.Cm24 | GLU 45 | 1.29x29 | VdWContact |
| ARG 6 | NTc.Cm24 | TYR 197 | 45.51x51 | Hydrophobic |
| ARG 6 | NTc.Cm24 | TYR 197 | 45.51x51 | VdWContact |
| ARG 6 | NTc.Cm24 | ARG 208 | 5.35x36 | HBAcceptor |
| ARG 6 | NTc.Cm24 | ARG 208 | 5.35x36 | VdWContact |
| ARG 6 | NTc.Cm24 | ASP 297 | 7.36x35 | Cationic |
| GLY 7 | NTc.Cm23 | ARG 208 | 5.35x36 | VdWContact |
| GLY 7 | NTc.Cm23 | ARG 278 | 6.62x62 | HBAcceptor |
| GLY 7 | NTc.Cm23 | ARG 278 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 274 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 274 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 274 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ARG 289 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | ARG 289 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 292 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 293 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 293 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 293 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm21 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 9 | NTc.Cm21 | ARG 289 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm20 | PRO 38 | - | Hydrophobic |
| LEU 10 | NTc.Cm20 | CYS 39 | - | HBAcceptor |
| LEU 10 | NTc.Cm20 | CYS 39 | - | VdWContact |
| LEU 10 | NTc.Cm20 | ARG 289 | 7.28x27 | HBAcceptor |
| ILE 12 | NTc.Cm18 | CYS 39 | - | VdWContact |
| ILE 12 | NTc.Cm18 | GLU 284 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ARG 289 | 7.28x27 | VdWContact |
| VAL 16 | NTc.Cm14 | ALA 36 | - | Hydrophobic |
| LYS 20 | NTc.Cm10 | TYR 25 | - | Hydrophobic |
| VAL 21 | NTc.Cm9 | TRP 15 | - | Hydrophobic |
| VAL 21 | NTc.Cm9 | TRP 15 | - | VdWContact |
| ILE 24 | NTc.Cm6 | MET 6 | - | Hydrophobic |
| ILE 24 | NTc.Cm6 | MET 6 | - | VdWContact |
| GLU 25 | NTc.Cm5 | MET 6 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | MET 6 | - | VdWContact |
| LYS 26 | NTc.Cm4 | ASP 3 | - | Cationic |
| LYS 26 | NTc.Cm4 | ASP 3 | - | HBDonor |
| LYS 26 | NTc.Cm4 | ASP 3 | - | VdWContact |
| LYS 26 | NTc.Cm4 | PHE 4 | - | VdWContact |
| ALA 27 | NTc.Cm3 | PHE 4 | - | HBAcceptor |
| ALA 27 | NTc.Cm3 | PHE 4 | - | HBDonor |
| ALA 27 | NTc.Cm3 | PHE 4 | - | Hydrophobic |
| ALA 27 | NTc.Cm3 | PHE 4 | - | VdWContact |
| ALA 27 | NTc.Cm3 | MET 6 | - | Hydrophobic |
| SER 28 | NTc.Cm2 | GLU 2 | - | VdWContact |
| SER 28 | NTc.Cm2 | ASP 3 | - | HBDonor |
| SER 28 | NTc.Cm2 | ASP 3 | - | VdWContact |
| ILE 29 | NTc.Cm1 | MET 1 | - | VdWContact |
| ILE 29 | NTc.Cm1 | GLU 2 | - | HBAcceptor |
| ILE 29 | NTc.Cm1 | GLU 2 | - | HBDonor |
| ILE 29 | NTc.Cm1 | GLU 2 | - | VdWContact |
| MET 30 | CX.1 | MET 1 | - | Hydrophobic |
| TYR 31 | CX.4 | GLU 2 | - | HBDonor |
| TYR 31 | CX.4 | GLU 2 | - | Hydrophobic |
| TYR 31 | CX.4 | GLU 2 | - | VdWContact |
| PRO 32 | CX.5 | ASN 202 | - | Hydrophobic |
| ASN 34 | cxb1.2 | VAL 187 | - | Hydrophobic |
| ASN 34 | cxb1.2 | VAL 187 | - | VdWContact |
| ASN 34 | cxb1.2 | ASP 199 | - | HBDonor |
| ASN 34 | cxb1.2 | ASP 199 | - | VdWContact |
| ASN 34 | cxb1.2 | ARG 208 | 5.35x36 | HBAcceptor |
| ASN 34 | cxb1.2 | ARG 208 | 5.35x36 | VdWContact |
| ASP 37 | cxb1.7 | ASN 202 | - | VdWContact |
| ILE 42 | cxb1.15 | PRO 38 | - | Hydrophobic |
| LYS 46 | B1.3 | GLU 7 | - | Cationic |
| LYS 46 | B1.3 | GLU 7 | - | HBDonor |
| LYS 46 | B1.3 | GLU 7 | - | VdWContact |
| GLN 51 | b1b2.4 | PRO 38 | - | Hydrophobic |
| ARG 52 | b1b2.6 | ALA 36 | - | VdWContact |
| CYS 53 | b1b2.7 | ALA 36 | - | HBDonor |
| CYS 53 | b1b2.7 | ALA 36 | - | VdWContact |
| LYS 59 | b1b2.14 | GLU 18 | - | Cationic |
| LYS 59 | b1b2.14 | GLU 18 | - | VdWContact |
| LYS 59 | b1b2.14 | ASP 19 | - | HBDonor |
| LYS 59 | b1b2.14 | ASP 19 | - | VdWContact |
| LYS 59 | b1b2.14 | LEU 20 | - | Hydrophobic |
| LYS 59 | b1b2.14 | TYR 23 | - | Hydrophobic |
| LYS 59 | b1b2.14 | TYR 23 | - | VdWContact |
| GLN 60 | b1b2.16 | TRP 15 | - | Hydrophobic |
| GLN 60 | b1b2.16 | TRP 15 | - | VdWContact |
| LEU 63 | B2.3 | PHE 14 | - | Hydrophobic |
| LEU 63 | B2.3 | PHE 14 | - | VdWContact |
| LEU 63 | B2.3 | TRP 15 | - | Hydrophobic |
| LEU 63 | B2.3 | TRP 15 | - | VdWContact |
| LEU 63 | B2.3 | GLU 18 | - | VdWContact |
| LEU 63 | B2.3 | LEU 20 | - | Hydrophobic |
| ILE 64 | B2.4 | MET 6 | - | Hydrophobic |
| ILE 64 | B2.4 | PHE 11 | - | Hydrophobic |
| ILE 64 | B2.4 | TRP 15 | - | Hydrophobic |
| ILE 64 | B2.4 | TRP 15 | - | VdWContact |
| LYS 67 | b2b3.2 | ASP 9 | - | HBDonor |
| LYS 67 | b2b3.2 | ASP 9 | - | VdWContact |
| LYS 67 | b2b3.2 | SER 10 | - | VdWContact |
| LYS 67 | b2b3.2 | PHE 11 | - | CationPi |
| LYS 67 | b2b3.2 | PHE 11 | - | Hydrophobic |
| LYS 67 | b2b3.2 | PHE 11 | - | VdWContact |
| LYS 67 | b2b3.2 | PHE 14 | - | Hydrophobic |
| LYS 67 | b2b3.2 | PHE 14 | - | VdWContact |
| VAL 68 | b2b3.3 | GLU 2 | - | Hydrophobic |
| VAL 68 | b2b3.3 | GLU 2 | - | VdWContact |
| VAL 68 | b2b3.3 | PHE 4 | - | Hydrophobic |
| VAL 68 | b2b3.3 | PHE 4 | - | VdWContact |
| LYS 71 | b2b3.12 | PHE 4 | - | Hydrophobic |
| LYS 71 | b2b3.12 | PHE 4 | - | VdWContact |
| LYS 71 | b2b3.12 | ASP 9 | - | Cationic |
| LYS 71 | b2b3.12 | ASP 9 | - | HBDonor |
| LYS 71 | b2b3.12 | ASP 9 | - | VdWContact |
| ASN 72 | B3.1 | GLU 2 | - | VdWContact |
