Predicted complex interactions
CXCL13_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 152
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | GLU 127 | 3.33x33 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 127 | 3.33x33 | HBDonor |
| VAL 1 | NTc.Cm32 | GLU 127 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm32 | PHE 130 | 3.36x36 | Hydrophobic |
| VAL 1 | NTc.Cm32 | PHE 130 | 3.36x36 | VdWContact |
| VAL 1 | NTc.Cm32 | PRO 215 | 5.42x43 | Hydrophobic |
| VAL 1 | NTc.Cm32 | PRO 215 | 5.42x43 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 267 | 6.51x51 | HBAcceptor |
| VAL 1 | NTc.Cm32 | TYR 267 | 6.51x51 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 267 | 6.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | LYS 126 | 3.32x32 | HBAcceptor |
| LEU 2 | NTc.Cm31 | LYS 126 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 264 | 6.48x48 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 267 | 6.51x51 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 267 | 6.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | GLU 300 | 7.39x38 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 300 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | ILE 304 | 7.43x42 | Hydrophobic |
| GLU 3 | NTc.Cm30 | ARG 208 | 5.35x36 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 208 | 5.35x36 | VdWContact |
| GLU 3 | NTc.Cm30 | ARG 212 | 5.39x40 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 212 | 5.39x40 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 212 | 5.39x40 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 267 | 6.51x51 | HBDonor |
| GLU 3 | NTc.Cm30 | TYR 267 | 6.51x51 | VdWContact |
| GLU 3 | NTc.Cm30 | LEU 271 | 6.55x55 | Hydrophobic |
| VAL 4 | NTc.Cm29 | LYS 108 | 2.64x64 | VdWContact |
| VAL 4 | NTc.Cm29 | LEU 296 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm29 | LEU 296 | 7.35x34 | VdWContact |
| VAL 4 | NTc.Cm29 | ASP 297 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | ASP 297 | 7.36x35 | VdWContact |
| VAL 4 | NTc.Cm29 | GLU 300 | 7.39x38 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLU 300 | 7.39x38 | VdWContact |
| TYR 5 | NTc.Cm28 | TRP 104 | 2.60x60 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TRP 104 | 2.60x60 | VdWContact |
| TYR 5 | NTc.Cm28 | LYS 108 | 2.64x64 | Hydrophobic |
| TYR 5 | NTc.Cm28 | LYS 108 | 2.64x64 | PiCation |
| TYR 5 | NTc.Cm28 | LYS 108 | 2.64x64 | VdWContact |
| TYR 6 | NTc.Cm27 | ARG 184 | 4.64x65 | VdWContact |
| TYR 6 | NTc.Cm27 | CYS 196 | 45.50x50 | HBDonor |
| TYR 6 | NTc.Cm27 | CYS 196 | 45.50x50 | VdWContact |
| TYR 6 | NTc.Cm27 | TYR 197 | 45.51x51 | Hydrophobic |
| TYR 6 | NTc.Cm27 | TYR 197 | 45.51x51 | VdWContact |
| TYR 6 | NTc.Cm27 | GLU 198 | 45.52x52 | Hydrophobic |
| TYR 6 | NTc.Cm27 | GLU 198 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | ARG 208 | 5.35x36 | VdWContact |
| THR 7 | NTc.Cm26 | ARG 289 | 7.28x27 | HBAcceptor |
| THR 7 | NTc.Cm26 | ARG 289 | 7.28x27 | VdWContact |
| THR 7 | NTc.Cm26 | ASP 293 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 293 | 7.32x31 | VdWContact |
| THR 7 | NTc.Cm26 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 9 | NTc.Cm24 | SER 189 | - | VdWContact |
| LEU 9 | NTc.Cm24 | ALA 195 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 9 | NTc.Cm24 | TYR 197 | 45.51x51 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 274 | 6.58x58 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 274 | 6.58x58 | HBDonor |
| ARG 10 | NTc.Cm23 | ASP 274 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | ARG 278 | 6.62x62 | VdWContact |
| ARG 10 | NTc.Cm23 | ARG 289 | 7.28x27 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 293 | 7.32x31 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 293 | 7.32x31 | HBDonor |
| ARG 10 | NTc.Cm23 | ASP 293 | 7.32x31 | VdWContact |
| CYS 11 | NTc.Cm22 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 11 | NTc.Cm22 | ARG 289 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm21 | PRO 38 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | CYS 39 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 39 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 39 | - | VdWContact |
| VAL 14 | NTc.Cm19 | GLU 284 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | GLU 284 | - | VdWContact |
| GLN 15 | NTc.Cm18 | ASP 35 | - | VdWContact |
| VAL 19 | NTc.Cm14 | PRO 30 | - | Hydrophobic |
| VAL 19 | NTc.Cm14 | LEU 33 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | LEU 20 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | TYR 23 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | TYR 23 | - | PiStacking |
| PHE 20 | NTc.Cm13 | TYR 23 | - | VdWContact |
| PHE 20 | NTc.Cm13 | PRO 30 | - | VdWContact |
| ARG 23 | NTc.Cm10 | MET 6 | - | Hydrophobic |
| ARG 23 | NTc.Cm10 | MET 6 | - | VdWContact |
| ARG 23 | NTc.Cm10 | PHE 11 | - | VdWContact |
| ARG 23 | NTc.Cm10 | TRP 15 | - | VdWContact |
| ARG 24 | NTc.Cm9 | SER 27 | - | VdWContact |
| PHE 25 | NTc.Cm8 | LEU 29 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | MET 6 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | MET 6 | - | VdWContact |
| ASP 27 | NTc.Cm6 | MET 6 | - | HBAcceptor |
| ASP 27 | NTc.Cm6 | MET 6 | - | VdWContact |
| ARG 28 | NTc.Cm5 | ASP 3 | - | Cationic |
| ARG 28 | NTc.Cm5 | ASP 3 | - | HBDonor |
| ARG 28 | NTc.Cm5 | ASP 3 | - | VdWContact |
| ARG 28 | NTc.Cm5 | PHE 4 | - | VdWContact |
| ILE 29 | NTc.Cm4 | ASP 3 | - | VdWContact |
| ILE 29 | NTc.Cm4 | PHE 4 | - | HBAcceptor |
| ILE 29 | NTc.Cm4 | PHE 4 | - | HBDonor |
| ILE 29 | NTc.Cm4 | PHE 4 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | PHE 4 | - | VdWContact |
| ILE 29 | NTc.Cm4 | MET 6 | - | Hydrophobic |
| GLN 30 | NTc.Cm3 | MET 1 | - | Hydrophobic |
| GLN 30 | NTc.Cm3 | MET 1 | - | VdWContact |
| GLN 30 | NTc.Cm3 | GLU 2 | - | VdWContact |
| ILE 31 | NTc.Cm2 | MET 1 | - | VdWContact |
| ILE 31 | NTc.Cm2 | GLU 2 | - | HBAcceptor |
| ILE 31 | NTc.Cm2 | GLU 2 | - | HBDonor |
| ILE 31 | NTc.Cm2 | GLU 2 | - | Hydrophobic |
| ILE 31 | NTc.Cm2 | GLU 2 | - | VdWContact |
| ILE 31 | NTc.Cm2 | PHE 4 | - | Hydrophobic |
| ASN 36 | cxb1.1 | TYR 197 | 45.51x51 | Hydrophobic |
| ASN 36 | cxb1.1 | ASP 199 | - | HBDonor |
| ASN 36 | cxb1.1 | ASP 199 | - | VdWContact |
| ASN 36 | cxb1.1 | THR 204 | 5.31x32 | VdWContact |
| PRO 39 | cxb1.6 | ALA 205 | 5.32x33 | Hydrophobic |
| ILE 44 | cxb1.14 | PRO 38 | - | Hydrophobic |
| LYS 47 | B1.1 | LEU 29 | - | Hydrophobic |
| ASN 49 | B1.3 | LEU 29 | - | VdWContact |
| ASN 49 | B1.3 | PHE 32 | - | VdWContact |
| SER 51 | B1.5 | PHE 32 | - | VdWContact |
| ILE 52 | B1.6 | ALA 37 | - | VdWContact |
| ILE 52 | B1.6 | PRO 38 | - | Hydrophobic |
| VAL 53 | B1.7 | ALA 36 | - | Hydrophobic |
| VAL 53 | B1.7 | ALA 36 | - | VdWContact |
| CYS 54 | b1b2.4 | ALA 36 | - | HBDonor |
| CYS 54 | b1b2.4 | ALA 36 | - | VdWContact |
| CYS 54 | b1b2.4 | PRO 38 | - | VdWContact |
| TRP 61 | b1b2.13 | LEU 20 | - | Hydrophobic |
| TRP 61 | b1b2.13 | TYR 23 | - | Hydrophobic |
| TRP 61 | b1b2.13 | TYR 23 | - | VdWContact |
| MET 65 | B2.2 | MET 6 | - | Hydrophobic |
| MET 65 | B2.2 | TRP 15 | - | Hydrophobic |
| MET 65 | B2.2 | TRP 15 | - | VdWContact |
| MET 66 | B2.3 | PHE 4 | - | Hydrophobic |
| MET 66 | B2.3 | PHE 4 | - | VdWContact |
| VAL 68 | B2.5 | PHE 14 | - | Hydrophobic |
| VAL 68 | B2.5 | TRP 15 | - | Hydrophobic |
| VAL 68 | B2.5 | TRP 15 | - | VdWContact |
| VAL 68 | B2.5 | GLU 18 | - | VdWContact |
| LEU 69 | B2.6 | PHE 4 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 4 | - | VdWContact |
| LEU 69 | B2.6 | MET 6 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 11 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 11 | - | VdWContact |
| ARG 70 | b2b3.2 | GLU 2 | - | Cationic |
| ARG 70 | b2b3.2 | GLU 2 | - | HBDonor |
| ARG 70 | b2b3.2 | GLU 2 | - | VdWContact |
| ARG 70 | b2b3.2 | PHE 4 | - | Hydrophobic |
| ARG 72 | b2b3.11 | SER 10 | - | VdWContact |
| ARG 72 | b2b3.11 | PHE 11 | - | CationPi |
| ARG 72 | b2b3.11 | PHE 11 | - | HBDonor |
| ARG 72 | b2b3.11 | PHE 11 | - | Hydrophobic |
| ARG 72 | b2b3.11 | PHE 11 | - | VdWContact |
