Predicted complex interactions
CXCL17_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 152
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| CYS 29 | NTc.Cm21 | ASN 188 | - | HBAcceptor |
| CYS 29 | NTc.Cm21 | ASN 188 | - | VdWContact |
| GLU 30 | NTc.Cm20 | ASN 188 | - | VdWContact |
| GLU 30 | NTc.Cm20 | PRO 189 | - | Hydrophobic |
| GLU 30 | NTc.Cm20 | PRO 189 | - | VdWContact |
| LYS 32 | NTc.Cm18 | SER 105 | 2.63x63 | VdWContact |
| LYS 32 | NTc.Cm18 | TRP 108 | 2.66x66 | VdWContact |
| LYS 32 | NTc.Cm18 | HIS 109 | 23.49x49 | VdWContact |
| LYS 32 | NTc.Cm18 | VAL 192 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | ASN 194 | - | HBDonor |
| LYS 32 | NTc.Cm18 | ASN 194 | - | VdWContact |
| TRP 34 | NTc.Cm16 | MET 34 | - | HBDonor |
| TRP 34 | NTc.Cm16 | MET 34 | - | Hydrophobic |
| TRP 34 | NTc.Cm16 | MET 34 | - | VdWContact |
| TRP 34 | NTc.Cm16 | LYS 38 | 1.24x24 | VdWContact |
| PHE 35 | NTc.Cm15 | LYS 38 | 1.24x24 | VdWContact |
| PHE 35 | NTc.Cm15 | VAL 42 | 1.28x28 | Hydrophobic |
| PHE 35 | NTc.Cm15 | VAL 42 | 1.28x28 | VdWContact |
| PHE 35 | NTc.Cm15 | HIS 273 | 6.58x58 | Hydrophobic |
| PHE 35 | NTc.Cm15 | ASP 291 | 7.32x31 | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 37 | - | VdWContact |
| LEU 36 | NTc.Cm14 | LYS 38 | 1.24x24 | VdWContact |
| LEU 36 | NTc.Cm14 | ASP 39 | 1.25x25 | HBAcceptor |
| LEU 36 | NTc.Cm14 | ASP 39 | 1.25x25 | VdWContact |
| LEU 36 | NTc.Cm14 | VAL 42 | 1.28x28 | Hydrophobic |
| LEU 36 | NTc.Cm14 | VAL 42 | 1.28x28 | VdWContact |
| ARG 37 | NTc.Cm13 | MET 34 | - | VdWContact |
| ARG 37 | NTc.Cm13 | CYS 36 | - | VdWContact |
| ARG 37 | NTc.Cm13 | ARG 37 | - | Hydrophobic |
| ARG 37 | NTc.Cm13 | ARG 37 | - | VdWContact |
| ARG 37 | NTc.Cm13 | LYS 38 | 1.24x24 | HBAcceptor |
| ARG 37 | NTc.Cm13 | LYS 38 | 1.24x24 | VdWContact |
| ALA 38 | NTc.Cm12 | CYS 36 | - | Hydrophobic |
| ALA 38 | NTc.Cm12 | CYS 36 | - | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 37 | - | HBAcceptor |
| ALA 38 | NTc.Cm12 | ARG 37 | - | VdWContact |
| ALA 38 | NTc.Cm12 | LYS 38 | 1.24x24 | HBDonor |
| ALA 38 | NTc.Cm12 | LYS 38 | 1.24x24 | Hydrophobic |
| ALA 38 | NTc.Cm12 | LYS 38 | 1.24x24 | VdWContact |
| ALA 38 | NTc.Cm12 | CYS 284 | 7.25x24 | VdWContact |
| ALA 38 | NTc.Cm12 | SER 287 | 7.28x27 | VdWContact |
| ALA 38 | NTc.Cm12 | GLN 288 | 7.29x28 | Hydrophobic |
| ALA 38 | NTc.Cm12 | GLN 288 | 7.29x28 | VdWContact |
| PRO 39 | NTc.Cm11 | CYS 36 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | CYS 36 | - | VdWContact |
| PRO 39 | NTc.Cm11 | ARG 37 | - | HBAcceptor |
| PRO 39 | NTc.Cm11 | ARG 37 | - | VdWContact |
| PRO 39 | NTc.Cm11 | CYS 284 | 7.25x24 | Hydrophobic |
| PRO 39 | NTc.Cm11 | CYS 284 | 7.25x24 | VdWContact |
| PRO 39 | NTc.Cm11 | GLU 285 | 7.26x25 | Hydrophobic |
| PRO 39 | NTc.Cm11 | GLN 288 | 7.29x28 | HBAcceptor |
| PRO 39 | NTc.Cm11 | GLN 288 | 7.29x28 | VdWContact |
| ARG 40 | NTc.Cm10 | ARG 37 | - | HBDonor |
| ARG 40 | NTc.Cm10 | ARG 37 | - | Hydrophobic |
| ARG 40 | NTc.Cm10 | ARG 37 | - | VdWContact |
| ARG 40 | NTc.Cm10 | ASP 39 | 1.25x25 | Cationic |
| ARG 40 | NTc.Cm10 | ASP 39 | 1.25x25 | HBDonor |
| ARG 40 | NTc.Cm10 | ASP 39 | 1.25x25 | Hydrophobic |
| ARG 40 | NTc.Cm10 | ASP 39 | 1.25x25 | VdWContact |
| CYS 56 | cxb1.6 | LEU 35 | - | Hydrophobic |
| CYS 56 | cxb1.6 | LEU 35 | - | VdWContact |
| ASP 57 | cxb1.7 | LEU 35 | - | Hydrophobic |
| ASP 57 | cxb1.7 | LEU 35 | - | VdWContact |
| PHE 59 | cxb1.11 | TYR 24 | - | Hydrophobic |
| PHE 59 | cxb1.11 | TYR 27 | - | Hydrophobic |
| PHE 59 | cxb1.11 | TYR 27 | - | VdWContact |
| PHE 59 | cxb1.11 | LEU 28 | - | Hydrophobic |
| PHE 59 | cxb1.11 | LEU 28 | - | VdWContact |
| PHE 59 | cxb1.11 | VAL 31 | - | Hydrophobic |
| PHE 59 | cxb1.11 | VAL 31 | - | VdWContact |
| PHE 59 | cxb1.11 | LEU 35 | - | Hydrophobic |
| PHE 59 | cxb1.11 | LEU 35 | - | VdWContact |
| LYS 60 | cxb1.14 | ALA 32 | - | Hydrophobic |
| LYS 60 | cxb1.14 | ALA 32 | - | VdWContact |
| LYS 60 | cxb1.14 | LEU 35 | - | Hydrophobic |
| LYS 60 | cxb1.14 | LEU 35 | - | VdWContact |
| LYS 60 | cxb1.14 | CYS 36 | - | Cationic |
| LYS 60 | cxb1.14 | CYS 36 | - | Hydrophobic |
| LYS 60 | cxb1.14 | CYS 36 | - | VdWContact |
| LYS 60 | cxb1.14 | CYS 284 | 7.25x24 | Cationic |
| LYS 60 | cxb1.14 | CYS 284 | 7.25x24 | VdWContact |
| ASN 62 | cxb1.16 | LEU 28 | - | Hydrophobic |
| VAL 63 | B1.2 | TYR 25 | - | HBAcceptor |
| VAL 63 | B1.2 | TYR 25 | - | Hydrophobic |
| VAL 63 | B1.2 | TYR 25 | - | VdWContact |
| VAL 63 | B1.2 | LEU 28 | - | Hydrophobic |
| VAL 63 | B1.2 | LEU 28 | - | VdWContact |
| VAL 63 | B1.2 | ASP 29 | - | VdWContact |
| THR 66 | B1.5 | TYR 25 | - | HBDonor |
| THR 66 | B1.5 | TYR 25 | - | VdWContact |
| ARG 70 | b1b2.3 | GLU 13 | - | Cationic |
| ARG 70 | b1b2.3 | GLU 13 | - | HBDonor |
| ARG 70 | b1b2.3 | GLU 13 | - | VdWContact |
| PRO 75 | b1b2.9 | TYR 24 | - | Hydrophobic |
| PRO 75 | b1b2.9 | TYR 24 | - | VdWContact |
| ASN 76 | b1b2.10 | TYR 24 | - | HBDonor |
| ASN 76 | b1b2.10 | TYR 24 | - | VdWContact |
| SER 79 | b1b2.14 | TYR 27 | - | VdWContact |
| CYS 82 | b1b2.18 | VAL 31 | - | Hydrophobic |
| CYS 82 | b1b2.18 | VAL 31 | - | VdWContact |
| GLN 83 | b1b2.19 | TYR 27 | - | Hydrophobic |
| GLN 83 | b1b2.19 | TYR 27 | - | VdWContact |
| LEU 86 | b1b2.22 | VAL 31 | - | Hydrophobic |
| LEU 86 | b1b2.22 | VAL 31 | - | VdWContact |
| LEU 86 | b1b2.22 | MET 34 | - | Hydrophobic |
| LEU 86 | b1b2.22 | MET 34 | - | VdWContact |
| LYS 87 | b1b2.23 | GLY 200 | - | VdWContact |
| LYS 87 | b1b2.23 | GLY 201 | - | HBDonor |
| LYS 87 | b1b2.23 | GLY 201 | - | VdWContact |
| GLN 88 | b1b2.24 | HIS 186 | - | Hydrophobic |
| GLN 88 | b1b2.24 | ASN 188 | - | HBAcceptor |
| GLN 88 | b1b2.24 | ASN 188 | - | VdWContact |
| GLN 90 | B2.1 | LYS 207 | 5.35x36 | VdWContact |
| GLN 90 | B2.1 | ASP 277 | 6.62x62 | HBDonor |
| GLN 90 | B2.1 | ASP 277 | 6.62x62 | VdWContact |
| LEU 91 | B2.2 | HIS 196 | 45.51x51 | Hydrophobic |
| LEU 91 | B2.2 | HIS 196 | 45.51x51 | VdWContact |
| LEU 91 | B2.2 | ALA 197 | 45.52x52 | VdWContact |
| LEU 91 | B2.2 | ASP 198 | - | Hydrophobic |
| LEU 91 | B2.2 | ASP 198 | - | VdWContact |
| LEU 91 | B2.2 | PHE 199 | - | Hydrophobic |
| LEU 91 | B2.2 | PHE 199 | - | VdWContact |
| ARG 92 | B2.3 | HIS 186 | - | HBDonor |
| ARG 92 | B2.3 | HIS 186 | - | VdWContact |
| ARG 92 | B2.3 | ASN 188 | - | HBDonor |
| ARG 92 | B2.3 | ASN 188 | - | VdWContact |
| ARG 92 | B2.3 | ASN 194 | - | Hydrophobic |
| ARG 92 | B2.3 | ASN 194 | - | VdWContact |
| ARG 92 | B2.3 | HIS 196 | 45.51x51 | Hydrophobic |
| ARG 92 | B2.3 | HIS 196 | 45.51x51 | VdWContact |
| SER 93 | B2.4 | LYS 38 | 1.24x24 | Anionic |
| SER 93 | B2.4 | LYS 38 | 1.24x24 | VdWContact |
| SER 93 | B2.4 | ASP 291 | 7.32x31 | HBDonor |
| SER 93 | B2.4 | ASP 291 | 7.32x31 | VdWContact |
| PHE 94 | B2.5 | LYS 207 | 5.35x36 | Hydrophobic |
| PHE 94 | B2.5 | LYS 207 | 5.35x36 | VdWContact |
| PHE 94 | B2.5 | ARG 211 | 5.39x40 | VdWContact |
| PHE 94 | B2.5 | HIS 273 | 6.58x58 | Hydrophobic |
| ALA 95 | B2.6 | HIS 196 | 45.51x51 | Hydrophobic |
| ALA 95 | B2.6 | HIS 196 | 45.51x51 | VdWContact |
| LEU 96 | b2b3.2 | LEU 49 | 1.35x35 | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 294 | 7.35x34 | Hydrophobic |
| LEU 96 | b2b3.2 | GLN 295 | 7.36x35 | Hydrophobic |
| LEU 96 | b2b3.2 | GLN 295 | 7.36x35 | VdWContact |
| PRO 97 | b2b3.3 | TYR 53 | 1.39x39 | Hydrophobic |
| PRO 97 | b2b3.3 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 97 | b2b3.3 | TRP 102 | 2.60x60 | VdWContact |
| PRO 97 | b2b3.3 | GLU 298 | 7.39x38 | VdWContact |
| PRO 97 | b2b3.3 | PHE 302 | 7.43x42 | Hydrophobic |
| LEU 98 | b2b3.4 | TYR 124 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | THR 125 | 3.33x33 | VdWContact |
| LEU 98 | b2b3.4 | PHE 128 | 3.36x36 | VdWContact |
