Predicted complex interactions
CXCL16_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 115
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | TYR 55 | 1.39x39 | VdWContact |
| ASN 1 | NTc.Cm56 | ASP 297 | 7.36x35 | VdWContact |
| ASN 1 | NTc.Cm56 | GLU 300 | 7.39x38 | Cationic |
| ASN 1 | NTc.Cm56 | GLU 300 | 7.39x38 | Hydrophobic |
| ASN 1 | NTc.Cm56 | GLU 300 | 7.39x38 | VdWContact |
| ASN 1 | NTc.Cm56 | ILE 304 | 7.43x42 | VdWContact |
| GLU 2 | NTc.Cm55 | ARG 184 | 4.64x65 | VdWContact |
| GLU 2 | NTc.Cm55 | ALA 195 | - | VdWContact |
| GLU 2 | NTc.Cm55 | CYS 196 | 45.50x50 | HBAcceptor |
| GLU 2 | NTc.Cm55 | CYS 196 | 45.50x50 | VdWContact |
| GLU 2 | NTc.Cm55 | TYR 197 | 45.51x51 | Hydrophobic |
| GLU 2 | NTc.Cm55 | TYR 197 | 45.51x51 | VdWContact |
| GLY 3 | NTc.Cm54 | TYR 197 | 45.51x51 | VdWContact |
| GLY 3 | NTc.Cm54 | GLU 198 | 45.52x52 | HBAcceptor |
| GLY 3 | NTc.Cm54 | GLU 198 | 45.52x52 | VdWContact |
| SER 4 | NTc.Cm53 | TYR 197 | 45.51x51 | VdWContact |
| SER 4 | NTc.Cm53 | GLU 198 | 45.52x52 | VdWContact |
| SER 4 | NTc.Cm53 | ARG 212 | 5.39x40 | HBAcceptor |
| SER 4 | NTc.Cm53 | ARG 212 | 5.39x40 | VdWContact |
| VAL 5 | NTc.Cm52 | VAL 187 | - | Hydrophobic |
| VAL 5 | NTc.Cm52 | VAL 187 | - | VdWContact |
| VAL 5 | NTc.Cm52 | TYR 197 | 45.51x51 | Hydrophobic |
| VAL 5 | NTc.Cm52 | TYR 197 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm52 | GLU 198 | 45.52x52 | HBDonor |
| VAL 5 | NTc.Cm52 | GLU 198 | 45.52x52 | VdWContact |
| VAL 5 | NTc.Cm52 | ASP 199 | - | VdWContact |
| THR 6 | NTc.Cm51 | MET 200 | - | HBAcceptor |
| THR 6 | NTc.Cm51 | MET 200 | - | Hydrophobic |
| THR 6 | NTc.Cm51 | MET 200 | - | VdWContact |
| THR 6 | NTc.Cm51 | ARG 212 | 5.39x40 | VdWContact |
| THR 6 | NTc.Cm51 | ARG 278 | 6.62x62 | HBAcceptor |
| THR 6 | NTc.Cm51 | ARG 278 | 6.62x62 | VdWContact |
| GLY 7 | NTc.Cm50 | ARG 278 | 6.62x62 | HBAcceptor |
| GLY 7 | NTc.Cm50 | ARG 278 | 6.62x62 | VdWContact |
| SER 8 | NTc.Cm49 | TYR 197 | 45.51x51 | HBDonor |
| SER 8 | NTc.Cm49 | TYR 197 | 45.51x51 | VdWContact |
| SER 8 | NTc.Cm49 | ARG 278 | 6.62x62 | VdWContact |
| SER 8 | NTc.Cm49 | ASP 293 | 7.32x31 | HBDonor |
| SER 8 | NTc.Cm49 | ASP 293 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm48 | ARG 289 | 7.28x27 | VdWContact |
| TYR 10 | NTc.Cm47 | CYS 39 | - | VdWContact |
| TYR 10 | NTc.Cm47 | GLU 40 | - | VdWContact |
| TYR 10 | NTc.Cm47 | PRO 41 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | PRO 41 | - | VdWContact |
| TYR 10 | NTc.Cm47 | ARG 289 | 7.28x27 | Hydrophobic |
| TYR 10 | NTc.Cm47 | ARG 289 | 7.28x27 | VdWContact |
| GLY 12 | NTc.Cm45 | PRO 38 | - | VdWContact |
| LYS 13 | NTc.Cm44 | PHE 11 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | PHE 11 | - | VdWContact |
| LYS 13 | NTc.Cm44 | TRP 15 | - | CationPi |
| LYS 13 | NTc.Cm44 | TRP 15 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | TRP 15 | - | VdWContact |
| LYS 13 | NTc.Cm44 | LEU 20 | - | VdWContact |
| LYS 13 | NTc.Cm44 | TYR 25 | - | VdWContact |
| LYS 13 | NTc.Cm44 | PRO 38 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | PRO 38 | - | VdWContact |
| ARG 14 | NTc.Cm43 | GLU 284 | - | Cationic |
| ILE 15 | NTc.Cm42 | TRP 15 | - | Hydrophobic |
| ILE 15 | NTc.Cm42 | TYR 23 | - | Hydrophobic |
| SER 19 | NTc.Cm38 | TYR 23 | - | VdWContact |
| PRO 21 | NTc.Cm36 | TYR 23 | - | VdWContact |
| SER 22 | NTc.Cm35 | GLU 18 | - | HBDonor |
| SER 22 | NTc.Cm35 | GLU 18 | - | VdWContact |
| SER 22 | NTc.Cm35 | TYR 23 | - | VdWContact |
| PHE 25 | NTc.Cm32 | PHE 14 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | PHE 14 | - | VdWContact |
| PHE 25 | NTc.Cm32 | TRP 15 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | TRP 15 | - | VdWContact |
| PHE 25 | NTc.Cm32 | GLU 18 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | GLU 18 | - | VdWContact |
| ARG 28 | NTc.Cm29 | ASP 13 | - | VdWContact |
| ARG 28 | NTc.Cm29 | PHE 14 | - | HBDonor |
| ARG 28 | NTc.Cm29 | PHE 14 | - | Hydrophobic |
| ARG 28 | NTc.Cm29 | PHE 14 | - | VdWContact |
| ARG 28 | NTc.Cm29 | LYS 16 | - | HBDonor |
| ARG 28 | NTc.Cm29 | LYS 16 | - | VdWContact |
| HIS 32 | NTc.Cm25 | PHE 14 | - | Hydrophobic |
| HIS 32 | NTc.Cm25 | PHE 14 | - | VdWContact |
| ARG 34 | NTc.Cm23 | SER 190 | - | VdWContact |
| ARG 34 | NTc.Cm23 | ASN 191 | - | HBDonor |
| ARG 34 | NTc.Cm23 | ASN 191 | - | VdWContact |
| HIS 37 | NTc.Cm20 | VAL 187 | - | Hydrophobic |
| HIS 37 | NTc.Cm20 | VAL 187 | - | VdWContact |
| HIS 37 | NTc.Cm20 | ASP 199 | - | HBDonor |
| HIS 37 | NTc.Cm20 | ASP 199 | - | VdWContact |
| ARG 38 | NTc.Cm19 | MET 200 | - | VdWContact |
| ARG 38 | NTc.Cm19 | GLY 201 | - | VdWContact |
| ARG 38 | NTc.Cm19 | ASN 202 | - | VdWContact |
| CYS 39 | NTc.Cm18 | MET 200 | - | VdWContact |
| CYS 39 | NTc.Cm18 | ASN 202 | - | VdWContact |
| LEU 40 | NTc.Cm17 | MET 200 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | ALA 205 | 5.32x33 | Hydrophobic |
| LEU 40 | NTc.Cm17 | ALA 205 | 5.32x33 | VdWContact |
| LEU 40 | NTc.Cm17 | MET 209 | 5.36x37 | Hydrophobic |
| LEU 40 | NTc.Cm17 | MET 209 | 5.36x37 | VdWContact |
| TYR 41 | NTc.Cm16 | ARG 278 | 6.62x62 | VdWContact |
| TYR 41 | NTc.Cm16 | GLN 280 | 6.64x64 | Hydrophobic |
| TYR 42 | NTc.Cm15 | GLU 284 | - | HBDonor |
| TYR 42 | NTc.Cm15 | GLU 284 | - | VdWContact |
| GLN 46 | NTc.Cm11 | SER 190 | - | VdWContact |
| GLN 46 | NTc.Cm11 | VAL 192 | - | VdWContact |
| LEU 47 | NTc.Cm10 | PHE 14 | - | Hydrophobic |
| LEU 47 | NTc.Cm10 | PHE 14 | - | VdWContact |
| LEU 47 | NTc.Cm10 | SER 190 | - | HBAcceptor |
| LEU 47 | NTc.Cm10 | SER 190 | - | VdWContact |
| LEU 48 | NTc.Cm9 | ASN 191 | - | VdWContact |
| TRP 50 | NTc.Cm7 | PHE 11 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | PHE 11 | - | PiStacking |
| TRP 50 | NTc.Cm7 | PHE 14 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | PHE 14 | - | VdWContact |
| TRP 50 | NTc.Cm7 | TRP 15 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | TRP 15 | - | VdWContact |
| ASN 56 | NTc.Cm1 | ASN 202 | - | HBAcceptor |
| ASN 56 | NTc.Cm1 | ASN 202 | - | VdWContact |
| ALA 82 | b1b2.6 | PHE 4 | - | Hydrophobic |
