Predicted complex interactions
CXCL17_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 148
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 22 | NTc.Cm28 | ASN 191 | - | HBAcceptor |
| LEU 22 | NTc.Cm28 | ASN 191 | - | VdWContact |
| GLU 28 | NTc.Cm22 | ASN 191 | - | HBAcceptor |
| GLU 28 | NTc.Cm22 | ASN 191 | - | Hydrophobic |
| GLU 28 | NTc.Cm22 | ASN 191 | - | VdWContact |
| GLU 28 | NTc.Cm22 | VAL 192 | - | Hydrophobic |
| CYS 29 | NTc.Cm21 | VAL 192 | - | VdWContact |
| GLU 30 | NTc.Cm20 | PRO 41 | - | Hydrophobic |
| GLU 30 | NTc.Cm20 | PRO 41 | - | VdWContact |
| GLU 30 | NTc.Cm20 | LYS 48 | 1.32x32 | Anionic |
| GLU 30 | NTc.Cm20 | LYS 48 | 1.32x32 | HBAcceptor |
| GLU 30 | NTc.Cm20 | LYS 48 | 1.32x32 | VdWContact |
| LYS 32 | NTc.Cm18 | PRO 41 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | PRO 41 | - | VdWContact |
| LYS 32 | NTc.Cm18 | SER 43 | - | VdWContact |
| LYS 32 | NTc.Cm18 | LEU 44 | - | HBDonor |
| LYS 32 | NTc.Cm18 | LEU 44 | - | VdWContact |
| LYS 32 | NTc.Cm18 | ASP 293 | 7.32x31 | VdWContact |
| ASP 33 | NTc.Cm17 | PRO 41 | - | Hydrophobic |
| ASP 33 | NTc.Cm17 | PRO 41 | - | VdWContact |
| PHE 35 | NTc.Cm15 | ARG 278 | 6.62x62 | HBAcceptor |
| PHE 35 | NTc.Cm15 | ARG 278 | 6.62x62 | VdWContact |
| PHE 35 | NTc.Cm15 | ASP 293 | 7.32x31 | VdWContact |
| LEU 36 | NTc.Cm14 | ASP 274 | 6.58x58 | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 278 | 6.62x62 | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 289 | 7.28x27 | HBAcceptor |
| LEU 36 | NTc.Cm14 | ARG 289 | 7.28x27 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ARG 289 | 7.28x27 | VdWContact |
| LEU 36 | NTc.Cm14 | ASN 290 | 7.29x28 | VdWContact |
| LEU 36 | NTc.Cm14 | ILE 292 | 7.31x30 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ILE 292 | 7.31x30 | VdWContact |
| LEU 36 | NTc.Cm14 | ASP 293 | 7.32x31 | HBDonor |
| LEU 36 | NTc.Cm14 | ASP 293 | 7.32x31 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ASP 293 | 7.32x31 | VdWContact |
| ARG 37 | NTc.Cm13 | CYS 39 | - | Cationic |
| ARG 37 | NTc.Cm13 | CYS 39 | - | HBDonor |
| ARG 37 | NTc.Cm13 | CYS 39 | - | VdWContact |
| ARG 37 | NTc.Cm13 | ARG 278 | 6.62x62 | HBAcceptor |
| ARG 37 | NTc.Cm13 | ARG 278 | 6.62x62 | VdWContact |
| ARG 37 | NTc.Cm13 | ARG 289 | 7.28x27 | Hydrophobic |
| ARG 37 | NTc.Cm13 | ARG 289 | 7.28x27 | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 278 | 6.62x62 | Hydrophobic |
| ALA 38 | NTc.Cm12 | ARG 278 | 6.62x62 | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 289 | 7.28x27 | VdWContact |
| PRO 39 | NTc.Cm11 | ARG 278 | 6.62x62 | VdWContact |
| ARG 40 | NTc.Cm10 | GLN 280 | 6.64x64 | HBDonor |
| ARG 40 | NTc.Cm10 | GLN 280 | 6.64x64 | Hydrophobic |
| ARG 40 | NTc.Cm10 | GLN 280 | 6.64x64 | VdWContact |
| ARG 40 | NTc.Cm10 | GLU 284 | - | VdWContact |
| ARG 41 | NTc.Cm9 | ASP 35 | - | HBDonor |
| ARG 41 | NTc.Cm9 | ASP 35 | - | VdWContact |
| ARG 41 | NTc.Cm9 | ALA 37 | - | HBDonor |
| ARG 41 | NTc.Cm9 | ALA 37 | - | VdWContact |
| ARG 41 | NTc.Cm9 | CYS 39 | - | Cationic |
| ARG 41 | NTc.Cm9 | CYS 39 | - | VdWContact |
| ARG 41 | NTc.Cm9 | GLU 284 | - | HBDonor |
| ARG 41 | NTc.Cm9 | GLU 284 | - | Hydrophobic |
| ARG 41 | NTc.Cm9 | GLU 284 | - | VdWContact |
| ARG 41 | NTc.Cm9 | THR 285 | 7.24x23 | HBDonor |
| ARG 41 | NTc.Cm9 | THR 285 | 7.24x23 | VdWContact |
| ARG 41 | NTc.Cm9 | CYS 286 | 7.25x24 | Cationic |
| ARG 41 | NTc.Cm9 | CYS 286 | 7.25x24 | VdWContact |
| LYS 42 | NTc.Cm8 | ALA 36 | - | Hydrophobic |
| LYS 42 | NTc.Cm8 | ALA 36 | - | VdWContact |
| LYS 42 | NTc.Cm8 | ALA 37 | - | VdWContact |
| LYS 42 | NTc.Cm8 | PRO 38 | - | VdWContact |
| PHE 43 | NTc.Cm7 | PRO 38 | - | Hydrophobic |
| PHE 43 | NTc.Cm7 | PRO 38 | - | VdWContact |
| MET 44 | NTc.Cm6 | LEU 33 | - | Hydrophobic |
| MET 44 | NTc.Cm6 | LEU 33 | - | VdWContact |
| MET 44 | NTc.Cm6 | ALA 36 | - | Hydrophobic |
| MET 44 | NTc.Cm6 | ALA 36 | - | VdWContact |
| MET 44 | NTc.Cm6 | ALA 37 | - | VdWContact |
| MET 44 | NTc.Cm6 | PRO 38 | - | VdWContact |
| LYS 51 | CX.4 | PRO 38 | - | Hydrophobic |
| LYS 52 | CX.5 | GLU 40 | - | Cationic |
| LYS 52 | CX.5 | GLU 40 | - | HBDonor |
| LYS 52 | CX.5 | GLU 40 | - | Hydrophobic |
| LYS 52 | CX.5 | GLU 40 | - | VdWContact |
| LYS 52 | CX.5 | PRO 41 | - | VdWContact |
| ASP 57 | cxb1.7 | PRO 38 | - | Hydrophobic |
| ASP 57 | cxb1.7 | PRO 38 | - | VdWContact |
| PHE 59 | cxb1.11 | ASN 202 | - | VdWContact |
| LYS 60 | cxb1.14 | GLU 284 | - | Cationic |
| LYS 60 | cxb1.14 | GLU 284 | - | VdWContact |
| GLN 83 | b1b2.19 | ASN 202 | - | HBDonor |
| GLN 83 | b1b2.19 | ASN 202 | - | VdWContact |
| LYS 87 | b1b2.23 | ARG 185 | - | VdWContact |
| LYS 87 | b1b2.23 | ASP 199 | - | Cationic |
| LYS 87 | b1b2.23 | ASP 199 | - | VdWContact |
| LYS 87 | b1b2.23 | GLY 201 | - | VdWContact |
| GLN 88 | b1b2.24 | VAL 187 | - | Hydrophobic |
| GLN 88 | b1b2.24 | VAL 187 | - | VdWContact |
| GLN 88 | b1b2.24 | TYR 188 | - | HBDonor |
| GLN 88 | b1b2.24 | TYR 188 | - | VdWContact |
| GLN 88 | b1b2.24 | SER 189 | - | VdWContact |
| GLN 90 | B2.1 | TYR 197 | 45.51x51 | VdWContact |
| GLN 90 | B2.1 | GLU 198 | 45.52x52 | HBAcceptor |
| GLN 90 | B2.1 | GLU 198 | 45.52x52 | VdWContact |
| LEU 91 | B2.2 | ARG 185 | - | Hydrophobic |
| LEU 91 | B2.2 | ARG 185 | - | VdWContact |
| LEU 91 | B2.2 | VAL 187 | - | Hydrophobic |
| LEU 91 | B2.2 | VAL 187 | - | VdWContact |
| LEU 91 | B2.2 | ALA 195 | - | VdWContact |
| LEU 91 | B2.2 | ASP 199 | - | Hydrophobic |
| LEU 91 | B2.2 | ASP 199 | - | VdWContact |
| ARG 92 | B2.3 | VAL 192 | - | VdWContact |
| ARG 92 | B2.3 | SER 193 | - | HBDonor |
| ARG 92 | B2.3 | SER 193 | - | VdWContact |
| ARG 92 | B2.3 | ALA 195 | - | Hydrophobic |
| ARG 92 | B2.3 | ALA 195 | - | VdWContact |
| SER 93 | B2.4 | TYR 197 | 45.51x51 | HBAcceptor |
| SER 93 | B2.4 | TYR 197 | 45.51x51 | VdWContact |
| PHE 94 | B2.5 | TYR 197 | 45.51x51 | VdWContact |
| PHE 94 | B2.5 | ARG 212 | 5.39x40 | VdWContact |
| PHE 94 | B2.5 | LEU 271 | 6.55x55 | Hydrophobic |
| PHE 94 | B2.5 | LEU 271 | 6.55x55 | VdWContact |
| PHE 94 | B2.5 | ASP 274 | 6.58x58 | VdWContact |
| PHE 94 | B2.5 | LEU 296 | 7.35x34 | Hydrophobic |
| ALA 95 | B2.6 | TRP 104 | 2.60x60 | Hydrophobic |
| ALA 95 | B2.6 | ALA 195 | - | Hydrophobic |
| ALA 95 | B2.6 | CYS 196 | 45.50x50 | VdWContact |
| LEU 96 | b2b3.2 | LYS 108 | 2.64x64 | VdWContact |
| LEU 96 | b2b3.2 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 296 | 7.35x34 | VdWContact |
| LEU 96 | b2b3.2 | ASP 297 | 7.36x35 | Hydrophobic |
| LEU 96 | b2b3.2 | ASP 297 | 7.36x35 | VdWContact |
| LEU 96 | b2b3.2 | GLU 300 | 7.39x38 | Hydrophobic |
| LEU 96 | b2b3.2 | GLU 300 | 7.39x38 | VdWContact |
| PRO 97 | b2b3.3 | TRP 104 | 2.60x60 | Hydrophobic |
| PRO 97 | b2b3.3 | TRP 104 | 2.60x60 | VdWContact |
| PRO 97 | b2b3.3 | LYS 126 | 3.32x32 | HBAcceptor |
| PRO 97 | b2b3.3 | LYS 126 | 3.32x32 | Hydrophobic |
| PRO 97 | b2b3.3 | LYS 126 | 3.32x32 | VdWContact |
| PRO 97 | b2b3.3 | ARG 184 | 4.64x65 | VdWContact |
| PRO 97 | b2b3.3 | GLU 300 | 7.39x38 | VdWContact |
| LEU 98 | b2b3.4 | LYS 126 | 3.32x32 | Anionic |
| LEU 98 | b2b3.4 | LYS 126 | 3.32x32 | HBAcceptor |
| LEU 98 | b2b3.4 | LYS 126 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | GLU 127 | 3.33x33 | Hydrophobic |
| LEU 98 | b2b3.4 | GLU 127 | 3.33x33 | VdWContact |
| LEU 98 | b2b3.4 | ARG 184 | 4.64x65 | Anionic |
| LEU 98 | b2b3.4 | ARG 184 | 4.64x65 | HBAcceptor |
| LEU 98 | b2b3.4 | ARG 184 | 4.64x65 | VdWContact |
| LEU 98 | b2b3.4 | TYR 267 | 6.51x51 | Hydrophobic |
| LEU 98 | b2b3.4 | TYR 267 | 6.51x51 | VdWContact |
| LEU 98 | b2b3.4 | LEU 271 | 6.55x55 | Hydrophobic |
| LEU 98 | b2b3.4 | LEU 271 | 6.55x55 | VdWContact |
