Predicted complex interactions
CXCL5_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 140
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 5 | NTc.Cm44 | VAL 192 | - | VdWContact |
| ALA 5 | NTc.Cm44 | SER 193 | - | VdWContact |
| ALA 6 | NTc.Cm43 | VAL 192 | - | VdWContact |
| ALA 6 | NTc.Cm43 | SER 193 | - | HBAcceptor |
| ALA 6 | NTc.Cm43 | SER 193 | - | VdWContact |
| VAL 7 | NTc.Cm42 | SER 107 | 2.63x63 | VdWContact |
| LEU 8 | NTc.Cm41 | PRO 41 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | PRO 41 | - | VdWContact |
| LEU 8 | NTc.Cm41 | VAL 192 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | VAL 192 | - | VdWContact |
| ARG 9 | NTc.Cm40 | TYR 197 | 45.51x51 | VdWContact |
| ARG 9 | NTc.Cm40 | TYR 267 | 6.51x51 | VdWContact |
| ARG 9 | NTc.Cm40 | LEU 296 | 7.35x34 | VdWContact |
| ARG 9 | NTc.Cm40 | ASP 297 | 7.36x35 | Cationic |
| ARG 9 | NTc.Cm40 | GLU 300 | 7.39x38 | Cationic |
| ARG 9 | NTc.Cm40 | GLU 300 | 7.39x38 | VdWContact |
| GLU 10 | NTc.Cm39 | TYR 197 | 45.51x51 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 208 | 5.35x36 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 208 | 5.35x36 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 212 | 5.39x40 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 278 | 6.62x62 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 278 | 6.62x62 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 278 | 6.62x62 | VdWContact |
| GLU 10 | NTc.Cm39 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 11 | NTc.Cm38 | VAL 187 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | VAL 192 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 197 | 45.51x51 | HBAcceptor |
| LEU 11 | NTc.Cm38 | TYR 197 | 45.51x51 | HBDonor |
| LEU 11 | NTc.Cm38 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 197 | 45.51x51 | VdWContact |
| LEU 11 | NTc.Cm38 | ARG 278 | 6.62x62 | HBAcceptor |
| LEU 11 | NTc.Cm38 | ARG 278 | 6.62x62 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 274 | 6.58x58 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 274 | 6.58x58 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 274 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | MET 277 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | GLU 284 | - | Cationic |
| ARG 12 | NTc.Cm37 | ASP 293 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 293 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 293 | 7.32x31 | VdWContact |
| CYS 13 | NTc.Cm36 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 13 | NTc.Cm36 | ARG 289 | 7.28x27 | VdWContact |
| VAL 14 | NTc.Cm35 | PRO 38 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | PRO 38 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 39 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 39 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 39 | - | VdWContact |
| LEU 16 | NTc.Cm33 | GLU 284 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | GLU 284 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ARG 289 | 7.28x27 | VdWContact |
| GLN 17 | NTc.Cm32 | ASP 35 | - | VdWContact |
| THR 19 | NTc.Cm30 | LEU 33 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | LEU 33 | - | VdWContact |
| THR 19 | NTc.Cm30 | ALA 36 | - | Hydrophobic |
| GLN 20 | NTc.Cm29 | TYR 23 | - | VdWContact |
| HIS 23 | NTc.Cm26 | LEU 20 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | LEU 20 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 23 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 23 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 25 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 25 | - | PiStacking |
| HIS 23 | NTc.Cm26 | TYR 25 | - | VdWContact |
| PRO 24 | NTc.Cm25 | TRP 15 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | TRP 15 | - | VdWContact |
| PRO 24 | NTc.Cm25 | LEU 20 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | LEU 20 | - | VdWContact |
| LYS 25 | NTc.Cm24 | TYR 25 | - | Hydrophobic |
| ILE 27 | NTc.Cm22 | MET 6 | - | Hydrophobic |
| SER 28 | NTc.Cm21 | MET 6 | - | HBAcceptor |
| SER 28 | NTc.Cm21 | MET 6 | - | VdWContact |
| SER 28 | NTc.Cm21 | GLU 7 | - | VdWContact |
| ASN 29 | NTc.Cm20 | PHE 4 | - | VdWContact |
| LEU 30 | NTc.Cm19 | ASP 3 | - | VdWContact |
| LEU 30 | NTc.Cm19 | PHE 4 | - | HBAcceptor |
| LEU 30 | NTc.Cm19 | PHE 4 | - | HBDonor |
| LEU 30 | NTc.Cm19 | PHE 4 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | PHE 4 | - | VdWContact |
| LEU 30 | NTc.Cm19 | MET 6 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | MET 6 | - | VdWContact |
| GLN 31 | NTc.Cm18 | MET 1 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | MET 1 | - | VdWContact |
| GLN 31 | NTc.Cm18 | GLU 2 | - | VdWContact |
| GLN 31 | NTc.Cm18 | ASP 3 | - | VdWContact |
| VAL 32 | NTc.Cm17 | MET 1 | - | VdWContact |
| VAL 32 | NTc.Cm17 | GLU 2 | - | HBAcceptor |
| VAL 32 | NTc.Cm17 | GLU 2 | - | HBDonor |
| VAL 32 | NTc.Cm17 | GLU 2 | - | VdWContact |
| VAL 32 | NTc.Cm17 | PHE 4 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | PHE 4 | - | VdWContact |
| PHE 33 | NTc.Cm16 | MET 1 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | SER 190 | - | VdWContact |
| ILE 35 | NTc.Cm14 | ASN 202 | - | Hydrophobic |
| ILE 35 | NTc.Cm14 | ASN 202 | - | VdWContact |
| PRO 37 | NTc.Cm12 | VAL 187 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | TYR 197 | 45.51x51 | Hydrophobic |
| PRO 37 | NTc.Cm12 | ASP 199 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | ASP 199 | - | VdWContact |
| PRO 37 | NTc.Cm12 | THR 204 | 5.31x32 | Hydrophobic |
| SER 40 | NTc.Cm9 | ASN 202 | - | VdWContact |
| VAL 45 | NTc.Cm4 | PRO 38 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | LEU 29 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | LEU 29 | - | VdWContact |
| LYS 49 | CX.1 | GLU 7 | - | Cationic |
| LYS 49 | CX.1 | GLU 7 | - | VdWContact |
| ASN 50 | CX.4 | LEU 29 | - | VdWContact |
| LYS 52 | cxb1.1 | LEU 29 | - | Hydrophobic |
| LYS 52 | cxb1.1 | LEU 29 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 38 | - | Hydrophobic |
| ILE 54 | cxb1.5 | LEU 29 | - | Hydrophobic |
| ILE 54 | cxb1.5 | LEU 29 | - | VdWContact |
| ILE 54 | cxb1.5 | LEU 33 | - | Hydrophobic |
| ILE 54 | cxb1.5 | LEU 33 | - | VdWContact |
| ILE 54 | cxb1.5 | ALA 36 | - | Hydrophobic |
| ILE 54 | cxb1.5 | ALA 36 | - | VdWContact |
| CYS 55 | cxb1.6 | ALA 36 | - | HBDonor |
| CYS 55 | cxb1.6 | ALA 36 | - | VdWContact |
| PHE 62 | B1.1 | TRP 15 | - | Hydrophobic |
| PHE 62 | B1.1 | TYR 23 | - | Hydrophobic |
| LYS 65 | B1.4 | PHE 14 | - | Hydrophobic |
| LYS 65 | B1.4 | GLU 18 | - | Cationic |
| LYS 65 | B1.4 | GLU 18 | - | HBDonor |
| LYS 65 | B1.4 | GLU 18 | - | VdWContact |
| VAL 66 | B1.5 | MET 6 | - | Hydrophobic |
| VAL 66 | B1.5 | MET 6 | - | VdWContact |
| VAL 66 | B1.5 | PHE 11 | - | Hydrophobic |
| VAL 66 | B1.5 | PHE 11 | - | VdWContact |
| VAL 66 | B1.5 | TRP 15 | - | Hydrophobic |
| VAL 66 | B1.5 | TRP 15 | - | VdWContact |
| LYS 69 | b1b2.4 | SER 10 | - | HBDonor |
| LYS 69 | b1b2.4 | SER 10 | - | VdWContact |
| LYS 69 | b1b2.4 | PHE 11 | - | CationPi |
| LYS 69 | b1b2.4 | PHE 11 | - | Hydrophobic |
| LYS 69 | b1b2.4 | PHE 11 | - | VdWContact |
| LYS 69 | b1b2.4 | PHE 14 | - | Hydrophobic |
| LYS 69 | b1b2.4 | PHE 14 | - | VdWContact |
| ILE 70 | b1b2.6 | PHE 4 | - | Hydrophobic |
| ILE 70 | b1b2.6 | PHE 4 | - | VdWContact |
| ILE 70 | b1b2.6 | PHE 11 | - | Hydrophobic |
| ILE 70 | b1b2.6 | PHE 11 | - | VdWContact |
