Predicted complex interactions
CXCL6_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 135
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 4 | NTc.Cm45 | VAL 192 | - | VdWContact |
| SER 4 | NTc.Cm45 | SER 193 | - | VdWContact |
| ALA 5 | NTc.Cm44 | PRO 41 | - | Hydrophobic |
| ALA 5 | NTc.Cm44 | VAL 192 | - | VdWContact |
| ALA 5 | NTc.Cm44 | SER 193 | - | HBAcceptor |
| ALA 5 | NTc.Cm44 | SER 193 | - | VdWContact |
| VAL 6 | NTc.Cm43 | SER 107 | 2.63x63 | VdWContact |
| VAL 6 | NTc.Cm43 | SER 193 | - | VdWContact |
| LEU 7 | NTc.Cm42 | PRO 41 | - | Hydrophobic |
| LEU 7 | NTc.Cm42 | PRO 41 | - | VdWContact |
| LEU 7 | NTc.Cm42 | VAL 192 | - | Hydrophobic |
| THR 8 | NTc.Cm41 | LYS 108 | 2.64x64 | VdWContact |
| THR 8 | NTc.Cm41 | TYR 197 | 45.51x51 | VdWContact |
| THR 8 | NTc.Cm41 | ASP 297 | 7.36x35 | HBDonor |
| THR 8 | NTc.Cm41 | ASP 297 | 7.36x35 | VdWContact |
| GLU 9 | NTc.Cm40 | TYR 197 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 208 | 5.35x36 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 208 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 212 | 5.39x40 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 212 | 5.39x40 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 212 | 5.39x40 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 278 | 6.62x62 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 278 | 6.62x62 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 278 | 6.62x62 | VdWContact |
| GLU 9 | NTc.Cm40 | LEU 296 | 7.35x34 | Hydrophobic |
| GLU 9 | NTc.Cm40 | LEU 296 | 7.35x34 | VdWContact |
| LEU 10 | NTc.Cm39 | VAL 187 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 197 | 45.51x51 | HBDonor |
| LEU 10 | NTc.Cm39 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 197 | 45.51x51 | VdWContact |
| LEU 10 | NTc.Cm39 | ARG 278 | 6.62x62 | HBAcceptor |
| LEU 10 | NTc.Cm39 | ARG 278 | 6.62x62 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 274 | 6.58x58 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 274 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 274 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 293 | 7.32x31 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 293 | 7.32x31 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 293 | 7.32x31 | VdWContact |
| CYS 12 | NTc.Cm37 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 12 | NTc.Cm37 | ARG 289 | 7.28x27 | VdWContact |
| THR 13 | NTc.Cm36 | PRO 38 | - | Hydrophobic |
| THR 13 | NTc.Cm36 | PRO 38 | - | VdWContact |
| THR 13 | NTc.Cm36 | CYS 39 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 39 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 39 | - | VdWContact |
| LEU 15 | NTc.Cm34 | GLU 284 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | GLU 284 | - | VdWContact |
| LEU 15 | NTc.Cm34 | ARG 289 | 7.28x27 | VdWContact |
| ARG 16 | NTc.Cm33 | ASP 35 | - | Cationic |
| ARG 16 | NTc.Cm33 | ASP 35 | - | VdWContact |
| THR 18 | NTc.Cm31 | LEU 33 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | LEU 33 | - | VdWContact |
| THR 18 | NTc.Cm31 | ALA 36 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 25 | - | HBDonor |
| ARG 20 | NTc.Cm29 | TYR 25 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 25 | - | VdWContact |
| VAL 21 | NTc.Cm28 | LEU 33 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | TRP 15 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | TRP 15 | - | VdWContact |
| PRO 23 | NTc.Cm26 | LEU 20 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | TRP 15 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | LEU 20 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | LEU 20 | - | VdWContact |
| ILE 26 | NTc.Cm23 | MET 6 | - | Hydrophobic |
| ILE 26 | NTc.Cm23 | MET 6 | - | VdWContact |
| GLY 27 | NTc.Cm22 | MET 6 | - | HBAcceptor |
| GLY 27 | NTc.Cm22 | MET 6 | - | VdWContact |
| GLY 27 | NTc.Cm22 | GLU 7 | - | VdWContact |
| LYS 28 | NTc.Cm21 | ASP 3 | - | Cationic |
| LYS 28 | NTc.Cm21 | ASP 3 | - | HBDonor |
| LYS 28 | NTc.Cm21 | ASP 3 | - | VdWContact |
| LYS 28 | NTc.Cm21 | PHE 4 | - | VdWContact |
| LEU 29 | NTc.Cm20 | ASP 3 | - | VdWContact |
| LEU 29 | NTc.Cm20 | PHE 4 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | PHE 4 | - | HBDonor |
| LEU 29 | NTc.Cm20 | PHE 4 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | PHE 4 | - | VdWContact |
| LEU 29 | NTc.Cm20 | MET 6 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | MET 1 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | MET 1 | - | VdWContact |
| GLN 30 | NTc.Cm19 | GLU 2 | - | VdWContact |
| GLN 30 | NTc.Cm19 | ASP 3 | - | HBDonor |
| GLN 30 | NTc.Cm19 | ASP 3 | - | VdWContact |
| VAL 31 | NTc.Cm18 | MET 1 | - | VdWContact |
| VAL 31 | NTc.Cm18 | GLU 2 | - | HBAcceptor |
| VAL 31 | NTc.Cm18 | GLU 2 | - | HBDonor |
| VAL 31 | NTc.Cm18 | GLU 2 | - | VdWContact |
| VAL 31 | NTc.Cm18 | PHE 4 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | MET 1 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | MET 1 | - | VdWContact |
| PHE 32 | NTc.Cm17 | SER 190 | - | VdWContact |
| PRO 36 | NTc.Cm13 | VAL 187 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | ASP 199 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | ASP 199 | - | VdWContact |
| PRO 36 | NTc.Cm13 | THR 204 | 5.31x32 | Hydrophobic |
| PRO 36 | NTc.Cm13 | THR 204 | 5.31x32 | VdWContact |
| GLN 37 | NTc.Cm12 | SER 189 | - | HBAcceptor |
| GLN 37 | NTc.Cm12 | SER 189 | - | VdWContact |
| SER 39 | NTc.Cm10 | ASN 202 | - | VdWContact |
| VAL 44 | NTc.Cm5 | PRO 38 | - | Hydrophobic |
| LEU 47 | NTc.Cm2 | LEU 29 | - | Hydrophobic |
| LYS 48 | NTc.Cm1 | GLU 7 | - | Cationic |
| LYS 48 | NTc.Cm1 | GLU 7 | - | VdWContact |
| LYS 48 | NTc.Cm1 | GLU 12 | - | Cationic |
| ASN 49 | CX.1 | LEU 29 | - | VdWContact |
| LYS 51 | CX.5 | LEU 29 | - | Hydrophobic |
| LYS 51 | CX.5 | LEU 29 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 38 | - | Hydrophobic |
| VAL 53 | cxb1.2 | LEU 29 | - | Hydrophobic |
| VAL 53 | cxb1.2 | LEU 33 | - | Hydrophobic |
| VAL 53 | cxb1.2 | ALA 36 | - | Hydrophobic |
| CYS 54 | cxb1.5 | ALA 36 | - | HBDonor |
| CYS 54 | cxb1.5 | ALA 36 | - | VdWContact |
| PRO 60 | cxb1.15 | TYR 23 | - | VdWContact |
| PHE 61 | cxb1.16 | TYR 23 | - | Hydrophobic |
| LYS 64 | B1.3 | PHE 14 | - | Hydrophobic |
| LYS 64 | B1.3 | GLU 18 | - | Cationic |
| LYS 64 | B1.3 | GLU 18 | - | HBDonor |
| LYS 64 | B1.3 | GLU 18 | - | VdWContact |
| VAL 65 | B1.4 | MET 6 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 11 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 11 | - | VdWContact |
| VAL 65 | B1.4 | TRP 15 | - | Hydrophobic |
| LYS 68 | B1.7 | SER 10 | - | HBDonor |
| LYS 68 | B1.7 | SER 10 | - | VdWContact |
| LYS 68 | B1.7 | PHE 11 | - | CationPi |
| LYS 68 | B1.7 | PHE 11 | - | Hydrophobic |
| LYS 68 | B1.7 | PHE 11 | - | VdWContact |
| LYS 68 | B1.7 | PHE 14 | - | Hydrophobic |
| LYS 68 | B1.7 | PHE 14 | - | VdWContact |
| ILE 69 | b1b2.4 | PHE 4 | - | Hydrophobic |
| ILE 69 | b1b2.4 | PHE 4 | - | VdWContact |
| ILE 69 | b1b2.4 | PHE 11 | - | Hydrophobic |
| ILE 69 | b1b2.4 | PHE 11 | - | VdWContact |
