Predicted complex interactions
CXCL7_HUMAN + CXCR2
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 131
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 19 | NTc.Cm44 | SER 193 | - | VdWContact |
| ASP 20 | NTc.Cm43 | SER 43 | - | HBAcceptor |
| ASP 20 | NTc.Cm43 | SER 43 | - | VdWContact |
| ASP 20 | NTc.Cm43 | LYS 48 | 1.32x32 | Anionic |
| ASP 20 | NTc.Cm43 | LYS 48 | 1.32x32 | HBAcceptor |
| ASP 20 | NTc.Cm43 | LYS 48 | 1.32x32 | VdWContact |
| SER 21 | NTc.Cm42 | LYS 48 | 1.32x32 | HBAcceptor |
| SER 21 | NTc.Cm42 | LYS 48 | 1.32x32 | VdWContact |
| SER 21 | NTc.Cm42 | VAL 109 | 2.65x65 | VdWContact |
| ASP 22 | NTc.Cm41 | SER 43 | - | VdWContact |
| ASP 22 | NTc.Cm41 | VAL 192 | - | Hydrophobic |
| ASP 22 | NTc.Cm41 | VAL 192 | - | VdWContact |
| LEU 23 | NTc.Cm40 | LYS 48 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm40 | LYS 48 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm40 | LYS 108 | 2.64x64 | Hydrophobic |
| LEU 23 | NTc.Cm40 | LYS 108 | 2.64x64 | VdWContact |
| LEU 23 | NTc.Cm40 | ASP 297 | 7.36x35 | VdWContact |
| TYR 24 | NTc.Cm39 | TRP 104 | 2.60x60 | Hydrophobic |
| TYR 24 | NTc.Cm39 | TRP 104 | 2.60x60 | VdWContact |
| TYR 24 | NTc.Cm39 | LYS 108 | 2.64x64 | Hydrophobic |
| TYR 24 | NTc.Cm39 | LYS 108 | 2.64x64 | VdWContact |
| GLU 26 | NTc.Cm37 | TYR 197 | 45.51x51 | HBAcceptor |
| GLU 26 | NTc.Cm37 | TYR 197 | 45.51x51 | VdWContact |
| GLU 26 | NTc.Cm37 | ARG 208 | 5.35x36 | Anionic |
| GLU 26 | NTc.Cm37 | ARG 208 | 5.35x36 | HBAcceptor |
| GLU 26 | NTc.Cm37 | ARG 208 | 5.35x36 | VdWContact |
| GLU 26 | NTc.Cm37 | ARG 212 | 5.39x40 | Anionic |
| GLU 26 | NTc.Cm37 | ARG 212 | 5.39x40 | HBAcceptor |
| GLU 26 | NTc.Cm37 | ARG 212 | 5.39x40 | VdWContact |
| GLU 26 | NTc.Cm37 | ARG 278 | 6.62x62 | Anionic |
| GLU 26 | NTc.Cm37 | ARG 278 | 6.62x62 | VdWContact |
| GLU 26 | NTc.Cm37 | LEU 296 | 7.35x34 | Hydrophobic |
| LEU 27 | NTc.Cm36 | VAL 187 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | TYR 197 | 45.51x51 | Hydrophobic |
| LEU 27 | NTc.Cm36 | TYR 197 | 45.51x51 | VdWContact |
| LEU 27 | NTc.Cm36 | ARG 278 | 6.62x62 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 274 | 6.58x58 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 274 | 6.58x58 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 274 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | MET 277 | 6.61x61 | VdWContact |
| ARG 28 | NTc.Cm35 | GLU 284 | - | Cationic |
| ARG 28 | NTc.Cm35 | ASP 293 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 293 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 293 | 7.32x31 | VdWContact |
| CYS 29 | NTc.Cm34 | ARG 289 | 7.28x27 | HBAcceptor |
| CYS 29 | NTc.Cm34 | ARG 289 | 7.28x27 | VdWContact |
| MET 30 | NTc.Cm33 | PRO 38 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | CYS 39 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 39 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 39 | - | VdWContact |
| ILE 32 | NTc.Cm31 | GLU 284 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ARG 289 | 7.28x27 | VdWContact |
| LYS 33 | NTc.Cm30 | ASP 35 | - | Cationic |
| LYS 33 | NTc.Cm30 | ASP 35 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | ASP 35 | - | VdWContact |
| THR 35 | NTc.Cm28 | LEU 33 | - | Hydrophobic |
| THR 35 | NTc.Cm28 | ALA 36 | - | Hydrophobic |
| SER 36 | NTc.Cm27 | TYR 23 | - | HBAcceptor |
| SER 36 | NTc.Cm27 | TYR 23 | - | VdWContact |
| ILE 38 | NTc.Cm25 | TYR 23 | - | VdWContact |
| ILE 38 | NTc.Cm25 | LEU 33 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | LEU 33 | - | VdWContact |
| HIS 39 | NTc.Cm24 | LEU 20 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 23 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 25 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | TRP 15 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | TRP 15 | - | VdWContact |
| PRO 40 | NTc.Cm23 | LEU 20 | - | Hydrophobic |
| GLN 44 | NTc.Cm19 | SER 8 | - | HBAcceptor |
| GLN 44 | NTc.Cm19 | SER 8 | - | VdWContact |
| SER 45 | NTc.Cm18 | MET 6 | - | VdWContact |
| LEU 46 | NTc.Cm17 | ASN 5 | - | VdWContact |
| LEU 46 | NTc.Cm17 | MET 6 | - | HBAcceptor |
| LEU 46 | NTc.Cm17 | MET 6 | - | HBDonor |
| LEU 46 | NTc.Cm17 | MET 6 | - | VdWContact |
| LEU 46 | NTc.Cm17 | PHE 11 | - | Hydrophobic |
| LEU 46 | NTc.Cm17 | PHE 11 | - | VdWContact |
| GLU 47 | NTc.Cm16 | PHE 4 | - | VdWContact |
| GLU 47 | NTc.Cm16 | ASN 191 | - | HBAcceptor |
| GLU 47 | NTc.Cm16 | ASN 191 | - | VdWContact |
| VAL 48 | NTc.Cm15 | ASP 3 | - | VdWContact |
| VAL 48 | NTc.Cm15 | PHE 4 | - | HBAcceptor |
| VAL 48 | NTc.Cm15 | PHE 4 | - | HBDonor |
| VAL 48 | NTc.Cm15 | PHE 4 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | PHE 4 | - | VdWContact |
| ILE 49 | NTc.Cm14 | ASP 3 | - | VdWContact |
| GLY 50 | NTc.Cm13 | MET 1 | - | VdWContact |
| GLY 50 | NTc.Cm13 | ASP 3 | - | HBDonor |
| GLY 50 | NTc.Cm13 | ASP 3 | - | VdWContact |
| GLY 52 | NTc.Cm11 | ASN 202 | - | VdWContact |
| THR 53 | NTc.Cm10 | VAL 187 | - | VdWContact |
| THR 53 | NTc.Cm10 | ASP 199 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | ASP 199 | - | VdWContact |
| ASN 56 | NTc.Cm7 | ASN 202 | - | VdWContact |
| VAL 58 | NTc.Cm5 | MET 1 | - | Hydrophobic |
| ILE 61 | NTc.Cm2 | PRO 38 | - | Hydrophobic |
| LEU 64 | CX.4 | LEU 29 | - | Hydrophobic |
| LEU 64 | CX.4 | LEU 29 | - | VdWContact |
| ARG 68 | cxb1.5 | LEU 29 | - | VdWContact |
| LYS 69 | cxb1.6 | PRO 38 | - | Hydrophobic |
| LYS 69 | cxb1.6 | GLU 40 | - | Cationic |
| CYS 71 | cxb1.10 | ALA 36 | - | HBDonor |
| CYS 71 | cxb1.10 | ALA 36 | - | VdWContact |
| ARG 78 | B1.3 | TRP 15 | - | Hydrophobic |
| ARG 78 | B1.3 | TRP 15 | - | VdWContact |
| ARG 78 | B1.3 | GLU 18 | - | Cationic |
| ARG 78 | B1.3 | GLU 18 | - | VdWContact |
| ARG 78 | B1.3 | ASP 19 | - | HBDonor |
| ARG 78 | B1.3 | LEU 20 | - | VdWContact |
| ARG 78 | B1.3 | TYR 23 | - | VdWContact |
| LYS 81 | B1.6 | PHE 14 | - | VdWContact |
| LYS 81 | B1.6 | GLU 18 | - | Cationic |
| LYS 81 | B1.6 | GLU 18 | - | HBDonor |
| LYS 81 | B1.6 | GLU 18 | - | VdWContact |
| ILE 82 | B1.7 | MET 6 | - | Hydrophobic |
| ILE 82 | B1.7 | PHE 11 | - | Hydrophobic |
| ILE 82 | B1.7 | PHE 11 | - | VdWContact |
| ILE 82 | B1.7 | PHE 14 | - | Hydrophobic |
| ILE 82 | B1.7 | PHE 14 | - | VdWContact |
| ILE 82 | B1.7 | TRP 15 | - | Hydrophobic |
| VAL 83 | b1b2.4 | MET 1 | - | Hydrophobic |
| VAL 83 | b1b2.4 | PHE 4 | - | Hydrophobic |
| VAL 83 | b1b2.4 | PHE 4 | - | VdWContact |
| LYS 85 | b1b2.7 | PHE 14 | - | CationPi |
| LYS 85 | b1b2.7 | PHE 14 | - | Hydrophobic |
| LYS 85 | b1b2.7 | PHE 14 | - | VdWContact |
| LYS 86 | b1b2.8 | PHE 4 | - | Hydrophobic |
| LYS 86 | b1b2.8 | MET 6 | - | Hydrophobic |
| LYS 86 | b1b2.8 | MET 6 | - | VdWContact |
| LEU 87 | b1b2.9 | MET 1 | - | Hydrophobic |
| LEU 87 | b1b2.9 | MET 1 | - | VdWContact |
